ISRG vs VRTX: Which is Better to Buy in 2026?

Side-by-side fundamental comparison based on AI analysis of SEC filings

AI Verdict

ISRG has stronger fundamentals based on our AI analysis.

ISRG
INTUITIVE SURGICAL INC
A
85%
Confidence
VS
VRTX
VERTEX PHARMACEUTICALS INC / MA
A
81%
Confidence

ISRG vs VRTX Fundamental Comparison

Metric ISRG VRTX
Revenue $2.8B $3.0B
Net Income $821.5M $1.0B
Net Margin 29.6% 34.5%
ROE 4.7% 5.3%
ROA 4.1% 3.9%
Current Ratio 4.61x 3.02x
Debt/Equity 0.00x 0.01x
EPS $2.28 $4.02

Green = Better metric | Red = Weaker metric

View Full ISRG Analysis →
View Full VRTX Analysis →
Browse Sectors: Technology Healthcare Finance Energy Consumer Industrial
Stock Lists: Top Rated Undervalued Growth Dividend

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ISRG vs VRTX: Frequently Asked Questions

Is ISRG or VRTX the better stock in 2026?

Based on dual AI fundamental analysis (Claude and ChatGPT), ISRG has stronger fundamentals. ISRG is graded A (85% confidence) while VRTX is graded A (81% confidence). This is not investment advice.

How does ISRG compare to VRTX fundamentally?

INTUITIVE SURGICAL INC has ROE of 4.7% vs VERTEX PHARMACEUTICALS INC / MA's 5.3%. Net margins are 29.6% vs 34.5% respectively.

Which stock pays higher dividends, ISRG or VRTX?

ISRG has a dividend yield of N/A or no dividend while VRTX has N/A or no dividend. Check individual stock pages for detailed dividend history and payout ratios.

Should I invest in ISRG or VRTX for long term?

For long-term investing, consider that ISRG has a A grade with 85% confidence, while VRTX has a A grade with 81% confidence. Higher confidence indicates more consistent fundamentals from SEC filings. This is not investment advice - always do your own research.

What do the AI models say about ISRG vs VRTX?

Our dual AI system (Claude by Anthropic and ChatGPT by OpenAI) analyzes SEC 10-K and 10-Q filings independently. For ISRG vs VRTX, the AI consensus favors ISRG based on fundamental metrics including revenue growth, profitability, ROE, and balance sheet strength.