ISRG vs VRTX: Which is Better to Buy in 2026?

Side-by-side fundamental comparison based on AI analysis of SEC filings

AI Verdict

ISRG has stronger fundamentals based on our AI analysis.

ISRG
INTUITIVE SURGICAL INC
BUY
90%
Confidence
VS
VRTX
VERTEX PHARMACEUTICALS INC / MA
BUY
86%
Confidence

ISRG vs VRTX Fundamental Comparison

Metric ISRG VRTX
Revenue $10.1B $12.0B
Net Income $2.9B $4.0B
Net Margin 28.4% 32.9%
ROE 16.0% 21.2%
ROA 14.0% 15.4%
Current Ratio 4.87x 2.90x
Debt/Equity 0.00x 0.01x
EPS $7.87 $15.32

Green = Better metric | Red = Weaker metric

View Full ISRG Analysis →
View Full VRTX Analysis →
Browse Sectors: Technology Healthcare Finance Energy Consumer Industrial
Stock Lists: Strong Buy Undervalued Growth Dividend

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ISRG vs VRTX: Frequently Asked Questions

Is ISRG or VRTX a better buy in 2026?

Based on dual AI fundamental analysis (Claude and ChatGPT), ISRG has stronger fundamentals. ISRG is rated BUY (90% confidence) while VRTX is rated BUY (86% confidence). This is not investment advice.

How does ISRG compare to VRTX fundamentally?

INTUITIVE SURGICAL INC has ROE of 16.0% vs VERTEX PHARMACEUTICALS INC / MA's 21.2%. Net margins are 28.4% vs 32.9% respectively.

Which stock pays higher dividends, ISRG or VRTX?

ISRG has a dividend yield of N/A or no dividend while VRTX has N/A or no dividend. Check individual stock pages for detailed dividend history and payout ratios.

Should I invest in ISRG or VRTX for long term?

For long-term investing, consider that ISRG has BUY rating with 90% confidence, while VRTX has BUY rating with 86% confidence. Higher confidence indicates more consistent fundamentals from SEC filings. This is not investment advice - always do your own research.

What do the AI models say about ISRG vs VRTX?

Our dual AI system (Claude by Anthropic and ChatGPT by OpenAI) analyzes SEC 10-K and 10-Q filings independently. For ISRG vs VRTX, the AI consensus favors ISRG based on fundamental metrics including revenue growth, profitability, ROE, and balance sheet strength.