← Back to All US Stocks

Wave Life Sciences Ltd. (WVE) Fundamental Analysis & AI Grade 2026

WVE Nasdaq Pharmaceutical Preparations U0 CIK: 0001631574
Updated This Month • Analysis: May 6, 2026 • SEC Data: 2026-03-31
Combined AI Grade
D
82% Confidence
N/A
D
82% Conf
Pending
Analysis scheduled

📊 WVE Key Takeaways

Revenue: $38.2M
Net Margin: -68.2%
Free Cash Flow: $-60.0M
Current Ratio: 11.26x
Debt/Equity: 0.00x
EPS: $-0.13
AI Grade: D with 82% confidence
Wave Life Sciences Ltd. (WVE) receives a D fundamental grade with 82% confidence from our AI analysis based on SEC 10-K filings. With revenue of $38.2M, net profit margin of -68.2%, and return on equity (ROE) of -5.1%, Wave Life Sciences Ltd. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete WVE stock analysis for 2026.

Is Wave Life Sciences Ltd. (WVE) a Good Investment?

Claude

Wave Life Sciences faces severe operational deterioration with revenue collapsing 60.5% YoY and generating negative free cash flow of -$60M annually. While the balance sheet provides near-term runway through substantial cash reserves, the unprofitable operations, declining sales, and negative margins indicate fundamental business failure, suggesting the core pipeline or commercial strategy is failing.

Wave Life Sciences Ltd. Key Strengths (WVE)

Claude
  • + Strong cash position of $544.6M provides operational runway for approximately 9 years at current burn rate
  • + Zero debt burden with Debt/Equity ratio of 0.00x and low liabilities of $71.8M
  • + Excellent liquidity ratios (Current Ratio 11.26x) enabling continued funding without asset sales or distress financing

WVE Stock Risks: Wave Life Sciences Ltd. Investment Risks

Claude
  • ! Revenue collapsed 60.5% year-over-year indicating severe commercial or clinical setbacks in core products
  • ! Negative free cash flow of -$60.0M annually with FCF margin of -156.9% showing operations are cash destructive
  • ! Deeply unprofitable with operating margin of -81.8% and net margin of -68.2%, generating $26.1M net losses
  • ! Diluted EPS deteriorated 72.9% YoY to -$0.13, reflecting worsening per-share economics
  • ! Cash burn will deplete reserves within 9 years even if stabilized at current levels without positive cash flow inflection

Key Metrics to Watch

Claude
  • * Quarterly revenue trend stabilization or further deterioration
  • * Operating cash flow path to positive; current -$59.6M burn is unsustainable long-term
  • * Clinical trial pipeline progress and regulatory approval timeline for next-stage products
  • * Cash runway duration and monthly cash burn rate acceleration/deceleration
  • * Gross margin recovery upon successful product commercialization to offset operating losses

Wave Life Sciences Ltd. (WVE) Financial Metrics & Key Ratios

Revenue
$38.2M
Net Income
$-26.1M
EPS (Diluted)
$-0.13
Free Cash Flow
$-60.0M
Total Assets
$583.5M
Cash Position
$544.6M

💡 AI Analyst Insight

Strong liquidity with a 11.26x current ratio provides a solid financial cushion.

WVE Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -81.8%
Net Margin -68.2%
ROE -5.1%
ROA -4.5%
FCF Margin -156.9%

WVE vs Healthcare Sector: How Wave Life Sciences Ltd. Compares

How Wave Life Sciences Ltd. compares to Healthcare sector averages

Net Margin
WVE -68.2%
vs
Sector Avg 12.0%
WVE Sector
ROE
WVE -5.1%
vs
Sector Avg 15.0%
WVE Sector
Current Ratio
WVE 11.3x
vs
Sector Avg 2.0x
WVE Sector
Debt/Equity
WVE 0.0x
vs
Sector Avg 0.6x
WVE Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Wave Life Sciences Ltd. Stock Overvalued? WVE Valuation Analysis 2026

Based on fundamental analysis, Wave Life Sciences Ltd. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-5.1%
Sector avg: 15%
Net Profit Margin
-68.2%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Wave Life Sciences Ltd. Balance Sheet: WVE Debt, Cash & Liquidity

Current Ratio
11.26x
Quick Ratio
11.26x
Debt/Equity
0.00x
Debt/Assets
12.3%
Interest Coverage
N/A
Long-term Debt
N/A

WVE Revenue & Earnings Growth: 5-Year Financial Trend

WVE 5-year financial data: Year 2021: Revenue $41.0M, Net Income -$149.9M, EPS N/A. Year 2022: Revenue $41.0M, Net Income -$122.2M, EPS $-2.36. Year 2023: Revenue $113.3M, Net Income -$161.8M, EPS $-2.05. Year 2024: Revenue $113.3M, Net Income -$161.8M, EPS $-2.05. Year 2025: Revenue $113.3M, Net Income -$57.5M, EPS $-0.54.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Wave Life Sciences Ltd.'s revenue has grown significantly by 177% over the 5-year period, indicating strong business expansion. The most recent EPS of $-0.54 indicates the company is currently unprofitable.

WVE Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-156.9%
Free cash flow / Revenue

WVE Quarterly Earnings & Performance

Quarterly financial performance data for Wave Life Sciences Ltd. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $9.2M -$26.1M $-0.13
Q2 2025 $8.7M -$31.6M $-0.25
Q1 2025 $9.2M -$31.6M $-0.24
Q2 2024 $19.7M -$21.1M $-0.20
Q1 2024 $12.5M -$27.4M $-0.24
Q3 2023 $285.0K $7.3M $0.07
Q2 2023 $375.0K -$21.1M $-0.20
Q1 2023 $1.8M -$27.4M $-0.27

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Wave Life Sciences Ltd. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$59.6M
Cash generated from operations
Capital Expenditures
$438.0K
Investment in assets
Dividends
None
No dividend program

WVE SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Wave Life Sciences Ltd. (CIK: 0001631574)

📋 Recent SEC Filings

Date Form Document Action
May 18, 2026 8-K d154261d8k.htm View →
May 7, 2026 DEF 14A d45078ddef14a.htm View →
Apr 30, 2026 10-K/A wve-20251231.htm View →
Apr 28, 2026 10-Q wve-20260331.htm View →
Apr 28, 2026 8-K d135689d8k.htm View →

Frequently Asked Questions about WVE

What is the AI rating for WVE?

Wave Life Sciences Ltd. (WVE) has an AI grade of D with 82% confidence, based on fundamental analysis of SEC EDGAR filings.

What are WVE's key strengths?

Claude: Strong cash position of $544.6M provides operational runway for approximately 9 years at current burn rate. Zero debt burden with Debt/Equity ratio of 0.00x and low liabilities of $71.8M.

What are the risks of investing in WVE?

Claude: Revenue collapsed 60.5% year-over-year indicating severe commercial or clinical setbacks in core products. Negative free cash flow of -$60.0M annually with FCF margin of -156.9% showing operations are cash destructive.

What is WVE's revenue and growth?

Wave Life Sciences Ltd. reported revenue of $38.2M.

Does WVE pay dividends?

Wave Life Sciences Ltd. does not currently pay dividends.

Where can I find WVE SEC filings?

Official SEC filings for Wave Life Sciences Ltd. (CIK: 0001631574) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is WVE's EPS?

Wave Life Sciences Ltd. has a diluted EPS of $-0.13.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is WVE's fundamental grade?

Based on our AI fundamental analysis in June 2026, Wave Life Sciences Ltd. has a D grade with 82% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is WVE stock overvalued or undervalued?

Valuation metrics for WVE: ROE of -5.1% (sector avg: 15%), net margin of -68.2% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is WVE's AI grade for 2026?

Our dual AI analysis gives Wave Life Sciences Ltd. a combined D grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is WVE's free cash flow?

Wave Life Sciences Ltd.'s operating cash flow is $-59.6M, with capital expenditures of $438.0K. FCF margin is -156.9%.

How does WVE compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -68.2% (avg: 12%), ROE -5.1% (avg: 15%), current ratio 11.26 (avg: 2).

Top Rated Stocks
AAPL 92% MSFT 92% FAST 92% ANET 88% RDDT 88% KNSL 88% MGRE 88% FIZZ 88% DECK 87% NVDA 87%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 6, 2026 | Data as of: 2026-03-31 | Powered by Claude AI