← Back to All US Stocks

Zenas BioPharma, Inc. (ZBIO) Stock Fundamental Analysis & AI Rating 2026

ZBIO Nasdaq Pharmaceutical Preparations DE CIK: 0001953926
Recently Updated • Analysis: Apr 19, 2026 • SEC Data: 2025-12-31
STRONG SELL
88% Conf
Pending
Analysis scheduled

📊 ZBIO Key Takeaways

Revenue: $10.0M
Net Margin: -3,777.4%
Free Cash Flow: $-172.4M
Current Ratio: 5.61x
Debt/Equity: 0.32x
EPS: $-8.44
AI Rating: STRONG SELL with 88% confidence
Zenas BioPharma, Inc. (ZBIO) receives a STRONG SELL rating with 88% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $10.0M, net profit margin of -3,777.4%, and return on equity (ROE) of -156.0%, Zenas BioPharma, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete ZBIO stock analysis for 2026.

Is Zenas BioPharma, Inc. (ZBIO) a Good Investment?

Claude

Zenas BioPharma exhibits severe financial distress with $10M in revenue against $383M in operating losses, representing a fundamentally unsustainable business model. Annual cash burn of $172.4M against $110.6M in available cash creates an 7-8 month runway, necessitating imminent capital raises that will significantly dilute shareholders. While adequate balance sheet liquidity and low leverage provide near-term survival capability, accelerating losses (-140.6% YoY) indicate deteriorating operational efficiency and fundamental product/revenue challenges.

Why Buy Zenas BioPharma, Inc. Stock? ZBIO Key Strengths

Claude
  • + Strong liquidity position with 5.61x current ratio providing runway for operations
  • + Manageable debt burden with 0.32x debt-to-equity ratio limiting bankruptcy risk
  • + EPS improved 29% YoY, indicating losses are contracting in relative terms

ZBIO Stock Risks: Zenas BioPharma, Inc. Investment Risks

Claude
  • ! Catastrophic cash burn of $172.4M annually with only $110.6M cash reserves (7-8 month runway)
  • ! Revenue growth flat at 0% YoY with losses of $37.77 per dollar of revenue, indicating pre-commercial stage with severe profitability challenges
  • ! Net losses accelerated 140.6% YoY, demonstrating deteriorating operational performance and rising cash consumption
  • ! Imminent need for dilutive capital raises or strategic alternatives (acquisition/merger) to continue operations

Key Metrics to Watch

Claude
  • * Quarterly cash burn rate trend and remaining cash runway
  • * Revenue growth trajectory and path to positive gross margins
  • * Capital raise announcements and dilution impact
  • * Clinical development milestones and regulatory progress
  • * Operating expense reduction initiatives

Zenas BioPharma, Inc. (ZBIO) Financial Metrics & Key Ratios

Revenue
$10.0M
Net Income
$-377.7M
EPS (Diluted)
$-8.44
Free Cash Flow
$-172.4M
Total Assets
$383.6M
Cash Position
$110.6M

💡 AI Analyst Insight

Strong liquidity with a 5.61x current ratio provides a solid financial cushion.

ZBIO Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -3,830.6%
Net Margin -3,777.4%
ROE -156.0%
ROA -98.5%
FCF Margin -1,723.5%

ZBIO vs Healthcare Sector: How Zenas BioPharma, Inc. Compares

How Zenas BioPharma, Inc. compares to Healthcare sector averages

Net Margin
ZBIO -3,777.4%
vs
Sector Avg 12.0%
ZBIO Sector
ROE
ZBIO -156.0%
vs
Sector Avg 15.0%
ZBIO Sector
Current Ratio
ZBIO 5.6x
vs
Sector Avg 2.0x
ZBIO Sector
Debt/Equity
ZBIO 0.3x
vs
Sector Avg 0.6x
ZBIO Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Zenas BioPharma, Inc. Stock Overvalued? ZBIO Valuation Analysis 2026

Based on fundamental analysis, Zenas BioPharma, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-156.0%
Sector avg: 15%
Net Profit Margin
-3,777.4%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.32x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Zenas BioPharma, Inc. Balance Sheet: ZBIO Debt, Cash & Liquidity

Current Ratio
5.61x
Quick Ratio
5.61x
Debt/Equity
0.32x
Debt/Assets
36.9%
Interest Coverage
N/A
Long-term Debt
$78.6M

ZBIO Revenue & Earnings Growth: 5-Year Financial Trend

ZBIO 5-year financial data: Year 2024: Revenue $50.0M, Net Income -$37.1M, EPS $-24.25. Year 2025: Revenue $10.0M, Net Income -$157.0M, EPS $-11.89.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Zenas BioPharma, Inc.'s revenue has declined by 80% over the 5-year period, indicating business contraction. The most recent EPS of $-11.89 indicates the company is currently unprofitable.

ZBIO Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-1,723.5%
Free cash flow / Revenue

ZBIO Quarterly Earnings & Performance

Quarterly financial performance data for Zenas BioPharma, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $10.0M -$27.8M $-1.22
Q2 2025 $10.0M -$27.8M $-1.25
Q1 2025 $10.0M -$27.8M $-0.80
Q3 2024 $50.0M -$12.5M $1.96

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Zenas BioPharma, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$172.3M
Cash generated from operations
Capital Expenditures
$18.0K
Investment in assets
Dividends
None
No dividend program

ZBIO SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Zenas BioPharma, Inc. (CIK: 0001953926)

📋 Recent SEC Filings

Date Form Document Action
Apr 2, 2026 4 xslF345X06/tm2611015-1_4seq1.xml View →
Apr 1, 2026 4 xslF345X06/tm2610877-1_4seq1.xml View →
Mar 31, 2026 4 xslF345X06/tm2610818-1_4seq1.xml View →
Mar 31, 2026 4 xslF345X06/tm2610681-1_4seq1.xml View →
Mar 31, 2026 8-K tm2610711d1_8k.htm View →

Frequently Asked Questions about ZBIO

What is the AI rating for ZBIO?

Zenas BioPharma, Inc. (ZBIO) has an AI rating of STRONG SELL with 88% confidence, based on fundamental analysis of SEC EDGAR filings.

What are ZBIO's key strengths?

Claude: Strong liquidity position with 5.61x current ratio providing runway for operations. Manageable debt burden with 0.32x debt-to-equity ratio limiting bankruptcy risk.

What are the risks of investing in ZBIO?

Claude: Catastrophic cash burn of $172.4M annually with only $110.6M cash reserves (7-8 month runway). Revenue growth flat at 0% YoY with losses of $37.77 per dollar of revenue, indicating pre-commercial stage with severe profitability challenges.

What is ZBIO's revenue and growth?

Zenas BioPharma, Inc. reported revenue of $10.0M.

Does ZBIO pay dividends?

Zenas BioPharma, Inc. does not currently pay dividends.

Where can I find ZBIO SEC filings?

Official SEC filings for Zenas BioPharma, Inc. (CIK: 0001953926) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is ZBIO's EPS?

Zenas BioPharma, Inc. has a diluted EPS of $-8.44.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is ZBIO a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Zenas BioPharma, Inc. has a STRONG SELL rating with 88% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is ZBIO stock overvalued or undervalued?

Valuation metrics for ZBIO: ROE of -156.0% (sector avg: 15%), net margin of -3,777.4% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy ZBIO stock in 2026?

Our dual AI analysis gives Zenas BioPharma, Inc. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is ZBIO's free cash flow?

Zenas BioPharma, Inc.'s operating cash flow is $-172.3M, with capital expenditures of $18.0K. FCF margin is -1,723.5%.

How does ZBIO compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -3,777.4% (avg: 12%), ROE -156.0% (avg: 15%), current ratio 5.61 (avg: 2).

Top Rated Stocks
NSSC 92% MLI 92% MELI 92% MDXG 92% MANH 92% INVA 92% GGG 92% GCT 92% FTNT 92% FSLR 92%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 19, 2026 | Data as of: 2025-12-31 | Powered by Claude AI