← Back to All US Stocks

Soleno Therapeutics Inc. (SLNO) Stock Fundamental Analysis & AI Rating 2026

SLNO Nasdaq Pharmaceutical Preparations DE CIK: 0001484565
Recently Updated • Analysis: Apr 16, 2026 • SEC Data: 2025-12-31
HOLD
68% Conf
Pending
Analysis scheduled

📊 SLNO Key Takeaways

Revenue: $190.4M
Net Margin: 11.0%
Free Cash Flow: $46.7M
Current Ratio: 5.80x
Debt/Equity: 0.11x
EPS: $0.39
AI Rating: HOLD with 68% confidence
Soleno Therapeutics Inc. (SLNO) receives a HOLD rating with 68% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $190.4M, net profit margin of 11.0%, and return on equity (ROE) of 4.6%, Soleno Therapeutics Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete SLNO stock analysis for 2026.

Is Soleno Therapeutics Inc. (SLNO) a Good Investment?

Claude

Soleno demonstrates strong balance sheet health, exceptional liquidity (5.8x current ratio), and solid free cash flow generation ($46.7M). However, the negative gross margin (-0.0%) and unexplained 13,024% revenue spike raise material concerns about operational sustainability and profitability quality, despite positive net income.

Why Buy Soleno Therapeutics Inc. Stock? SLNO Key Strengths

Claude
  • + Exceptional liquidity with 5.80x current ratio and $70.1M cash on hand
  • + Strong free cash flow of $46.7M with 24.5% FCF margin demonstrates cash generation capability
  • + Conservative capital structure with 0.11x debt-to-equity ratio and low financial risk
  • + Positive net income of $20.9M and operating cash flow of $46.8M indicate functioning core operations
  • + Minimal capital expenditure requirements ($73.0K) suggest efficient asset base

SLNO Stock Risks: Soleno Therapeutics Inc. Investment Risks

Claude
  • ! Negative gross margin (-0.0%) indicates products are unprofitable at unit level, unsustainable without explanation
  • ! Anomalous 13,024% YoY revenue growth suggests acquisition/one-time event; quality and sustainability of growth unclear
  • ! Weak interest coverage ratio of 1.7x leaves limited margin of safety for debt service
  • ! Disconnect between negative gross profit and positive net income suggests non-operating gains masking operational weakness
  • ! Pharmaceutical sector regulatory and approval risks; high insider activity (11 Form 4s in 90 days) warrants monitoring

Key Metrics to Watch

Claude
  • * Gross margin trend - must turn positive for sustainable profitability
  • * Revenue composition and sustainability - breakdown of the 13,024% YoY increase (acquisition vs. organic growth)
  • * Interest coverage ratio improvement - need expansion above 1.7x for debt safety
  • * Operating cash flow consistency - verify $46.8M is recurring not anomalous
  • * COGS and manufacturing efficiency trends - critical to understand negative gross margin drivers

Soleno Therapeutics Inc. (SLNO) Financial Metrics & Key Ratios

Revenue
$190.4M
Net Income
$20.9M
EPS (Diluted)
$0.39
Free Cash Flow
$46.7M
Total Assets
$563.8M
Cash Position
$70.1M

💡 AI Analyst Insight

The 24.5% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 5.80x current ratio provides a solid financial cushion.

SLNO Profit Margin, ROE & Profitability Analysis

Gross Margin 0.0%
Operating Margin 4.9%
Net Margin 11.0%
ROE 4.6%
ROA 3.7%
FCF Margin 24.5%

SLNO vs Healthcare Sector: How Soleno Therapeutics Inc. Compares

How Soleno Therapeutics Inc. compares to Healthcare sector averages

Net Margin
SLNO 11.0%
vs
Sector Avg 12.0%
SLNO Sector
ROE
SLNO 4.6%
vs
Sector Avg 15.0%
SLNO Sector
Current Ratio
SLNO 5.8x
vs
Sector Avg 2.0x
SLNO Sector
Debt/Equity
SLNO 0.1x
vs
Sector Avg 0.6x
SLNO Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Soleno Therapeutics Inc. Stock Overvalued? SLNO Valuation Analysis 2026

Based on fundamental analysis, Soleno Therapeutics Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
4.6%
Sector avg: 15%
Net Profit Margin
11.0%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.11x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Soleno Therapeutics Inc. Balance Sheet: SLNO Debt, Cash & Liquidity

Current Ratio
5.80x
Quick Ratio
5.55x
Debt/Equity
0.11x
Debt/Assets
20.2%
Interest Coverage
1.72x
Long-term Debt
$49.8M

SLNO Revenue & Earnings Growth: 5-Year Financial Trend

SLNO 5-year financial data: Year 2025: Revenue $190.4M, Net Income -$39.0M, EPS $-2.36.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Soleno Therapeutics Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-2.36 indicates the company is currently unprofitable.

SLNO Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
24.5%
Free cash flow / Revenue

SLNO Quarterly Earnings & Performance

Quarterly financial performance data for Soleno Therapeutics Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $66.0M -$4.7M $-0.45
Q2 2025 $32.7M -$4.7M $-0.09

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Soleno Therapeutics Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$46.8M
Cash generated from operations
Stock Buybacks
$100.1M
Shares repurchased (TTM)
Capital Expenditures
$73.0K
Investment in assets
Dividends
None
No dividend program

SLNO SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Soleno Therapeutics Inc. (CIK: 0001484565)

📋 Recent SEC Filings

Date Form Document Action
Apr 7, 2026 8-K d141594d8k.htm View →
Apr 6, 2026 8-K d142985d8k.htm View →
Mar 31, 2026 4 xslF345X06/form4-04012026_120401.xml View →
Mar 31, 2026 4 xslF345X06/form4-04012026_120437.xml View →
Mar 16, 2026 8-K d107502d8k.htm View →

Frequently Asked Questions about SLNO

What is the AI rating for SLNO?

Soleno Therapeutics Inc. (SLNO) has an AI rating of HOLD with 68% confidence, based on fundamental analysis of SEC EDGAR filings.

What are SLNO's key strengths?

Claude: Exceptional liquidity with 5.80x current ratio and $70.1M cash on hand. Strong free cash flow of $46.7M with 24.5% FCF margin demonstrates cash generation capability.

What are the risks of investing in SLNO?

Claude: Negative gross margin (-0.0%) indicates products are unprofitable at unit level, unsustainable without explanation. Anomalous 13,024% YoY revenue growth suggests acquisition/one-time event; quality and sustainability of growth unclear.

What is SLNO's revenue and growth?

Soleno Therapeutics Inc. reported revenue of $190.4M.

Does SLNO pay dividends?

Soleno Therapeutics Inc. does not currently pay dividends.

Where can I find SLNO SEC filings?

Official SEC filings for Soleno Therapeutics Inc. (CIK: 0001484565) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is SLNO's EPS?

Soleno Therapeutics Inc. has a diluted EPS of $0.39.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is SLNO a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Soleno Therapeutics Inc. has a HOLD rating with 68% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is SLNO stock overvalued or undervalued?

Valuation metrics for SLNO: ROE of 4.6% (sector avg: 15%), net margin of 11.0% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy SLNO stock in 2026?

Our dual AI analysis gives Soleno Therapeutics Inc. a combined HOLD rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is SLNO's free cash flow?

Soleno Therapeutics Inc.'s operating cash flow is $46.8M, with capital expenditures of $73.0K. FCF margin is 24.5%.

How does SLNO compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 11.0% (avg: 12%), ROE 4.6% (avg: 15%), current ratio 5.80 (avg: 2).

Top Rated Stocks
NSSC 92% MLI 92% MELI 92% MDXG 92% MANH 92% INVA 92% GGG 92% GCT 92% FTNT 92% FSLR 92%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 16, 2026 | Data as of: 2025-12-31 | Powered by Claude AI