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Plus Therapeutics, Inc.. (PSTV) Stock Fundamental Analysis & AI Rating 2026

PSTV Nasdaq Surgical & Medical Instruments & Apparatus DE CIK: 0001095981
Recently Updated • Analysis: Apr 14, 2026 • SEC Data: 2025-12-31
STRONG SELL
95% Conf
Pending
Analysis scheduled

📊 PSTV Key Takeaways

Revenue: $5.2M
Net Margin: -429.4%
Free Cash Flow: $-20.8M
Current Ratio: 1.23x
Debt/Equity: 0.95x
EPS: $-0.29
AI Rating: STRONG SELL with 95% confidence
Plus Therapeutics, Inc.. (PSTV) receives a STRONG SELL rating with 95% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $5.2M, net profit margin of -429.4%, and return on equity (ROE) of -560.2%, Plus Therapeutics, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PSTV stock analysis for 2026.

Is Plus Therapeutics, Inc.. (PSTV) a Good Investment?

Claude

PSTV is a micro-revenue medical device company in acute financial distress, burning cash at 4x its annual revenue with only ~2.5 months of runway remaining. The company cannot cover operating expenses or debt service from operations, indicating a fundamentally broken business model requiring immediate capital injection or strategic restructuring to survive.

Why Buy Plus Therapeutics, Inc.. Stock? PSTV Key Strengths

Claude
  • + Maintains $4.3M cash reserve providing minimal operational runway
  • + Loss trajectory improved year-over-year with net loss declining 72.5%
  • + Operates in high-growth medical device sector with potential long-term tailwinds

PSTV Stock Risks: Plus Therapeutics, Inc.. Investment Risks

Claude
  • ! Catastrophic cash burn of -$20.8M annually against $5.2M revenue with <3 months liquidity runway
  • ! Grossly inadequate gross margin of 7.9% indicating either severe pricing failure or near-total operational underutilization
  • ! Cannot service debt obligations from operations with -250.8x interest coverage, forcing reliance on cash depletion

Key Metrics to Watch

Claude
  • * Monthly cash burn rate and projected cash depletion date
  • * Revenue inflection point and gross margin recovery trajectory
  • * Debt covenant compliance and refinancing/capital raise announcements

Plus Therapeutics, Inc.. (PSTV) Financial Metrics & Key Ratios

Revenue
$5.2M
Net Income
$-22.4M
EPS (Diluted)
$-0.29
Free Cash Flow
$-20.8M
Total Assets
$16.3M
Cash Position
$4.3M

💡 AI Analyst Insight

Plus Therapeutics, Inc.. presents a mixed fundamental picture. Review the detailed metrics above to form your own investment thesis.

PSTV Profit Margin, ROE & Profitability Analysis

Gross Margin 7.9%
Operating Margin -293.5%
Net Margin -429.4%
ROE -560.2%
ROA -137.1%
FCF Margin -399.8%

PSTV vs Healthcare Sector: How Plus Therapeutics, Inc.. Compares

How Plus Therapeutics, Inc.. compares to Healthcare sector averages

Net Margin
PSTV -429.4%
vs
Sector Avg 12.0%
PSTV Sector
ROE
PSTV -560.2%
vs
Sector Avg 15.0%
PSTV Sector
Current Ratio
PSTV 1.2x
vs
Sector Avg 2.0x
PSTV Sector
Debt/Equity
PSTV 0.9x
vs
Sector Avg 0.6x
PSTV Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Plus Therapeutics, Inc.. Stock Overvalued? PSTV Valuation Analysis 2026

Based on fundamental analysis, Plus Therapeutics, Inc.. shows some fundamental concerns relative to the Healthcare sector in 2026.

Return on Equity
-560.2%
Sector avg: 15%
Net Profit Margin
-429.4%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.95x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Plus Therapeutics, Inc.. Balance Sheet: PSTV Debt, Cash & Liquidity

Current Ratio
1.23x
Quick Ratio
1.22x
Debt/Equity
0.95x
Debt/Assets
75.5%
Interest Coverage
-250.79x
Long-term Debt
$3.8M

PSTV Revenue & Earnings Growth: 5-Year Financial Trend

PSTV 5-year financial data: Year 2016: Revenue $4.8M, Net Income N/A, EPS N/A. Year 2017: Revenue $4.7M, Net Income N/A, EPS N/A. Year 2018: Revenue $3.7M, Net Income N/A, EPS N/A. Year 2024: Revenue $5.8M, Net Income -$13.3M, EPS $-4.24. Year 2025: Revenue $5.8M, Net Income -$13.0M, EPS $-2.34.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Plus Therapeutics, Inc..'s revenue has grown significantly by 20% over the 5-year period, indicating strong business expansion. The most recent EPS of $-2.34 indicates the company is currently unprofitable.

PSTV Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-399.8%
Free cash flow / Revenue

PSTV Quarterly Earnings & Performance

Quarterly financial performance data for Plus Therapeutics, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $1.4M -$2.9M $-0.04
Q2 2025 $1.3M -$2.9M $-0.01
Q1 2025 $1.1M -$3.3M $-0.75
Q1 2019 $703.0K -$3.2M N/A
Q3 2018 $467.0K -$2.3M N/A
Q2 2018 $660.0K -$3.7M N/A
Q1 2018 $591.0K -$4.4M N/A
Q3 2017 $467.0K -$4.8M N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Plus Therapeutics, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$20.8M
Cash generated from operations
Stock Buybacks
$374.0K
Shares repurchased (TTM)
Capital Expenditures
$67.0K
Investment in assets
Dividends
None
No dividend program

PSTV SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Plus Therapeutics, Inc.. (CIK: 0001095981)

📋 Recent SEC Filings

Date Form Document Action
Apr 9, 2026 8-K pstv-20260408.htm View →
Apr 8, 2026 8-K pstv-20260408.htm View →
Apr 2, 2026 8-K pstv-20260401.htm View →
Apr 1, 2026 4 xslF345X06/ownership.xml View →
Apr 1, 2026 4 xslF345X06/ownership.xml View →

Frequently Asked Questions about PSTV

What is the AI rating for PSTV?

Plus Therapeutics, Inc.. (PSTV) has an AI rating of STRONG SELL with 95% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PSTV's key strengths?

Claude: Maintains $4.3M cash reserve providing minimal operational runway. Loss trajectory improved year-over-year with net loss declining 72.5%.

What are the risks of investing in PSTV?

Claude: Catastrophic cash burn of -$20.8M annually against $5.2M revenue with <3 months liquidity runway. Grossly inadequate gross margin of 7.9% indicating either severe pricing failure or near-total operational underutilization.

What is PSTV's revenue and growth?

Plus Therapeutics, Inc.. reported revenue of $5.2M.

Does PSTV pay dividends?

Plus Therapeutics, Inc.. does not currently pay dividends.

Where can I find PSTV SEC filings?

Official SEC filings for Plus Therapeutics, Inc.. (CIK: 0001095981) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PSTV's EPS?

Plus Therapeutics, Inc.. has a diluted EPS of $-0.29.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is PSTV a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Plus Therapeutics, Inc.. has a STRONG SELL rating with 95% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is PSTV stock overvalued or undervalued?

Valuation metrics for PSTV: ROE of -560.2% (sector avg: 15%), net margin of -429.4% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy PSTV stock in 2026?

Our dual AI analysis gives Plus Therapeutics, Inc.. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is PSTV's free cash flow?

Plus Therapeutics, Inc..'s operating cash flow is $-20.8M, with capital expenditures of $67.0K. FCF margin is -399.8%.

How does PSTV compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -429.4% (avg: 12%), ROE -560.2% (avg: 15%), current ratio 1.23 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 14, 2026 | Data as of: 2025-12-31 | Powered by Claude AI