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Plus Therapeutics, Inc.. (PSTV) Fundamental Analysis & AI Grade 2026

PSTV Nasdaq Surgical & Medical Instruments & Apparatus DE CIK: 0001095981
Recently Updated • Analysis: May 31, 2026 • SEC Data: 2026-03-31
Combined AI Grade
D
92% Confidence
N/A
D
92% Conf
Pending
Analysis scheduled

📊 PSTV Key Takeaways

Revenue: $1.0M
Net Margin: -675.7%
Free Cash Flow: $-7.1M
Current Ratio: 2.27x
Debt/Equity: 0.32x
EPS: $-1.05
AI Grade: D with 92% confidence
Plus Therapeutics, Inc.. (PSTV) receives a D fundamental grade with 92% confidence from our AI analysis based on SEC 10-K filings. With revenue of $1.0M, net profit margin of -675.7%, and return on equity (ROE) of -58.1%, Plus Therapeutics, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PSTV stock analysis for 2026.

Is Plus Therapeutics, Inc.. (PSTV) a Good Investment?

Claude

PSTV faces severe financial distress with -$7.1M operating loss on only $1.0M revenue (-10.5% YoY) and -$6.2M operating cash burn. With $3.0M cash against ~$7M annual burn rate, the company has critical liquidity runway of less than 6 months. While gross margin of 40.1% suggests product viability, the company is destroying shareholder value (-58.1% ROE) with no visible profitability trajectory.

Plus Therapeutics, Inc.. Key Strengths (PSTV)

Claude
  • + Gross margin of 40.1% indicates product-level unit economics and pricing power
  • + Current ratio of 2.27x and quick ratio of 2.25x provide near-term liquidity buffer
  • + Moderate leverage at 0.32x debt-to-equity limits immediate refinancing pressure

PSTV Stock Risks: Plus Therapeutics, Inc.. Investment Risks

Claude
  • ! Critical cash runway: $3.0M cash against $7.1M annual burn rate equals ~5 months survival
  • ! Revenue declining 10.5% YoY despite fundamental need to scale operations
  • ! Massive operating losses with -692.5% operating margin and negative 116.7x interest coverage
  • ! Negative returns destroying equity (-58.1% ROE, -34.9% ROA) with no profitability roadmap
  • ! Limited debt/equity capacity to raise capital given current financial performance

Key Metrics to Watch

Claude
  • * Cash burn rate trend and months of cash runway remaining
  • * Revenue growth/decline trajectory - stabilization required for survival
  • * Operating expense levels - ability to reach cash flow breakeven
  • * Capital raise activity - necessity and terms of additional financing

Plus Therapeutics, Inc.. (PSTV) Financial Metrics & Key Ratios

Revenue
$1.0M
Net Income
$-6.9M
EPS (Diluted)
$-1.05
Free Cash Flow
$-7.1M
Total Assets
$19.9M
Cash Position
$3.0M

💡 AI Analyst Insight

Strong liquidity with a 2.27x current ratio provides a solid financial cushion.

PSTV Profit Margin, ROE & Profitability Analysis

Gross Margin 40.1%
Operating Margin -692.5%
Net Margin -675.7%
ROE -58.1%
ROA -34.9%
FCF Margin -686.4%

PSTV vs Healthcare Sector: How Plus Therapeutics, Inc.. Compares

How Plus Therapeutics, Inc.. compares to Healthcare sector averages

Net Margin
PSTV -675.7%
vs
Sector Avg 12.0%
PSTV Sector
ROE
PSTV -58.1%
vs
Sector Avg 15.0%
PSTV Sector
Current Ratio
PSTV 2.3x
vs
Sector Avg 2.0x
PSTV Sector
Debt/Equity
PSTV 0.3x
vs
Sector Avg 0.6x
PSTV Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Plus Therapeutics, Inc.. Stock Overvalued? PSTV Valuation Analysis 2026

Based on fundamental analysis, Plus Therapeutics, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-58.1%
Sector avg: 15%
Net Profit Margin
-675.7%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.32x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Plus Therapeutics, Inc.. Balance Sheet: PSTV Debt, Cash & Liquidity

Current Ratio
2.27x
Quick Ratio
2.25x
Debt/Equity
0.32x
Debt/Assets
39.9%
Interest Coverage
-116.70x
Long-term Debt
$3.8M

PSTV Revenue & Earnings Growth: 5-Year Financial Trend

PSTV 5-year financial data: Year 2016: Revenue $4.8M, Net Income N/A, EPS N/A. Year 2017: Revenue $4.7M, Net Income N/A, EPS N/A. Year 2018: Revenue $3.7M, Net Income N/A, EPS N/A. Year 2024: Revenue $5.8M, Net Income -$13.3M, EPS $-4.24. Year 2025: Revenue $5.8M, Net Income -$13.0M, EPS $-2.34.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Plus Therapeutics, Inc..'s revenue has grown significantly by 20% over the 5-year period, indicating strong business expansion. The most recent EPS of $-2.34 indicates the company is currently unprofitable.

PSTV Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-686.4%
Free cash flow / Revenue

PSTV Quarterly Earnings & Performance

Quarterly financial performance data for Plus Therapeutics, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $1.0M -$6.9M $-1.05
Q3 2025 $1.4M -$2.9M $-0.04
Q2 2025 $1.3M -$2.9M $-0.01
Q1 2025 $1.1M -$3.3M $-0.75
Q1 2019 $703.0K -$3.2M N/A
Q3 2018 $467.0K -$2.3M N/A
Q2 2018 $660.0K -$3.7M N/A
Q1 2018 $591.0K -$4.4M N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Plus Therapeutics, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$6.2M
Cash generated from operations
Stock Buybacks
$374.0K
Shares repurchased (TTM)
Capital Expenditures
$818.0K
Investment in assets
Dividends
None
No dividend program

PSTV SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Plus Therapeutics, Inc.. (CIK: 0001095981)

📋 Recent SEC Filings

Date Form Document Action
May 18, 2026 4 xslF345X06/ownership.xml View →
May 18, 2026 4 xslF345X06/ownership.xml View →
May 18, 2026 4 xslF345X06/ownership.xml View →
May 18, 2026 4 xslF345X06/ownership.xml View →
May 18, 2026 4 xslF345X06/ownership.xml View →

Frequently Asked Questions about PSTV

What is the AI rating for PSTV?

Plus Therapeutics, Inc.. (PSTV) has an AI grade of D with 92% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PSTV's key strengths?

Claude: Gross margin of 40.1% indicates product-level unit economics and pricing power. Current ratio of 2.27x and quick ratio of 2.25x provide near-term liquidity buffer.

What are the risks of investing in PSTV?

Claude: Critical cash runway: $3.0M cash against $7.1M annual burn rate equals ~5 months survival. Revenue declining 10.5% YoY despite fundamental need to scale operations.

What is PSTV's revenue and growth?

Plus Therapeutics, Inc.. reported revenue of $1.0M.

Does PSTV pay dividends?

Plus Therapeutics, Inc.. does not currently pay dividends.

Where can I find PSTV SEC filings?

Official SEC filings for Plus Therapeutics, Inc.. (CIK: 0001095981) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PSTV's EPS?

Plus Therapeutics, Inc.. has a diluted EPS of $-1.05.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is PSTV's fundamental grade?

Based on our AI fundamental analysis in May 2026, Plus Therapeutics, Inc.. has a D grade with 92% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is PSTV stock overvalued or undervalued?

Valuation metrics for PSTV: ROE of -58.1% (sector avg: 15%), net margin of -675.7% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is PSTV's AI grade for 2026?

Our dual AI analysis gives Plus Therapeutics, Inc.. a combined D grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is PSTV's free cash flow?

Plus Therapeutics, Inc..'s operating cash flow is $-6.2M, with capital expenditures of $818.0K. FCF margin is -686.4%.

How does PSTV compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -675.7% (avg: 12%), ROE -58.1% (avg: 15%), current ratio 2.27 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 31, 2026 | Data as of: 2026-03-31 | Powered by Claude AI