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Prothena Corp. Public Ltd. Co (PRTA) Fundamental Analysis & AI Grade 2026

PRTA Nasdaq Pharmaceutical Preparations L2 CIK: 0001559053
Updated This Month • Analysis: May 9, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
68% Confidence
N/A
C
68% Conf
Pending
Analysis scheduled

📊 PRTA Key Takeaways

Revenue: $51.1M
Net Margin: 64.1%
Free Cash Flow: $28.8M
Current Ratio: 10.43x
Debt/Equity: 0.00x
EPS: $0.60
AI Grade: C with 68% confidence
Prothena Corp. Public Ltd. Co (PRTA) receives a C fundamental grade with 68% confidence from our AI analysis based on SEC 10-K filings. With revenue of $51.1M, net profit margin of 64.1%, and return on equity (ROE) of 10.5%, Prothena Corp. Public Ltd. Co demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PRTA stock analysis for 2026.

Is Prothena Corp. Public Ltd. Co (PRTA) a Good Investment?

Claude

Prothena faces severe fundamental deterioration with 31.5% revenue decline and near-complete earnings collapse (99.6% YoY), indicating critical business model failure in its pharmaceutical operations likely from pipeline shortfalls or product losses. While the fortress balance sheet ($329.5M cash, zero debt) delays insolvency, absent credible turnaround evidence or pipeline catalysts, the company will face accelerating shareholder value destruction.

Prothena Corp. Public Ltd. Co Key Strengths (PRTA)

Claude
  • + Fortress balance sheet with $329.5M cash and zero debt provides 2+ year runway for turnaround attempts
  • + Positive free cash flow of $28.8M despite revenue collapse demonstrates operational resilience
  • + Operating margin of 58.8% suggests core profitable business segments remain viable

PRTA Stock Risks: Prothena Corp. Public Ltd. Co Investment Risks

Claude
  • ! Catastrophic 31.5% revenue decline indicates loss of major products, patents, or market exclusivity in pharmaceutical company
  • ! Net income collapse of 99.6% represents business model deterioration, not temporary cyclical weakness
  • ! Elevated insider Form 4 activity (8 filings) suggests management uncertainty or credibility issues regarding turnaround path
  • ! Continued revenue erosion will eventually exceed cash burn capacity despite current balance sheet strength
  • ! As biotech company, pipeline risk is existential; no visible evidence of value-accretive assets or clinical success

Key Metrics to Watch

Claude
  • * Quarterly revenue trends and YoY rate of decline stabilization
  • * Clinical trial progress and regulatory approvals for pipeline programs
  • * Operating cash flow sustainability and cash burn rate as percentage of reserves
  • * Management changes, strategic partnerships, or capital deployment announcements
  • * Cash runway estimate based on current burn rate

Prothena Corp. Public Ltd. Co (PRTA) Financial Metrics & Key Ratios

Revenue
$51.1M
Net Income
$32.7M
EPS (Diluted)
$0.60
Free Cash Flow
$28.8M
Total Assets
$349.9M
Cash Position
$329.5M

💡 AI Analyst Insight

The 56.3% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 10.43x current ratio provides a solid financial cushion.

PRTA Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin 58.8%
Net Margin 64.1%
ROE 10.5%
ROA 9.4%
FCF Margin 56.3%

PRTA vs Healthcare Sector: How Prothena Corp. Public Ltd. Co Compares

How Prothena Corp. Public Ltd. Co compares to Healthcare sector averages

Net Margin
PRTA 64.1%
vs
Sector Avg 12.0%
PRTA Sector
ROE
PRTA 10.5%
vs
Sector Avg 15.0%
PRTA Sector
Current Ratio
PRTA 10.4x
vs
Sector Avg 2.0x
PRTA Sector
Debt/Equity
PRTA 0.0x
vs
Sector Avg 0.6x
PRTA Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Prothena Corp. Public Ltd. Co Stock Overvalued? PRTA Valuation Analysis 2026

Based on fundamental analysis, Prothena Corp. Public Ltd. Co appears fundamentally strong relative to the Healthcare sector in 2026.

Return on Equity
10.5%
Sector avg: 15%
Net Profit Margin
64.1%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Prothena Corp. Public Ltd. Co Balance Sheet: PRTA Debt, Cash & Liquidity

Current Ratio
10.43x
Quick Ratio
10.43x
Debt/Equity
0.00x
Debt/Assets
10.7%
Interest Coverage
N/A
Long-term Debt
N/A

PRTA Revenue & Earnings Growth: 5-Year Financial Trend

PRTA 5-year financial data: Year 2021: Revenue $200.6M, Net Income -$77.7M, EPS $-1.95. Year 2022: Revenue $200.6M, Net Income -$111.1M, EPS $-2.78. Year 2023: Revenue $200.6M, Net Income $67.0M, EPS $1.38. Year 2024: Revenue $135.2M, Net Income -$116.9M, EPS $-2.47. Year 2025: Revenue $135.2M, Net Income -$147.0M, EPS $-2.76.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Prothena Corp. Public Ltd. Co's revenue has declined by 33% over the 5-year period, indicating business contraction. The most recent EPS of $-2.76 indicates the company is currently unprofitable.

PRTA Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
56.3%
Free cash flow / Revenue

PRTA Quarterly Earnings & Performance

Quarterly financial performance data for Prothena Corp. Public Ltd. Co including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $2.8M $32.7M $0.60
Q3 2025 $970.0K -$36.5M $-0.68
Q2 2025 $4.4M -$5.4M $-0.10
Q1 2025 $50.0K -$60.2M $-1.12
Q3 2024 $970.0K $21.9M $0.38
Q2 2024 $4.0M -$5.4M $-0.10
Q1 2024 $50.0K -$46.9M $-0.89
Q3 2023 $1.5M $21.9M $0.38

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Prothena Corp. Public Ltd. Co Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$28.9M
Cash generated from operations
Stock Buybacks
$6.9M
Shares repurchased (TTM)
Capital Expenditures
$110.0K
Investment in assets
Dividends
None
No dividend program

PRTA SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Prothena Corp. Public Ltd. Co (CIK: 0001559053)

📋 Recent SEC Filings

Date Form Document Action
May 26, 2026 4 xslF345X06/primary_doc.xml View →
May 15, 2026 4 xslF345X06/form4.xml View →
May 15, 2026 4 xslF345X06/form4.xml View →
May 15, 2026 4 xslF345X06/form4.xml View →
May 15, 2026 4 xslF345X06/form4.xml View →

Frequently Asked Questions about PRTA

What is the AI rating for PRTA?

Prothena Corp. Public Ltd. Co (PRTA) has an AI grade of C with 68% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PRTA's key strengths?

Claude: Fortress balance sheet with $329.5M cash and zero debt provides 2+ year runway for turnaround attempts. Positive free cash flow of $28.8M despite revenue collapse demonstrates operational resilience.

What are the risks of investing in PRTA?

Claude: Catastrophic 31.5% revenue decline indicates loss of major products, patents, or market exclusivity in pharmaceutical company. Net income collapse of 99.6% represents business model deterioration, not temporary cyclical weakness.

What is PRTA's revenue and growth?

Prothena Corp. Public Ltd. Co reported revenue of $51.1M.

Does PRTA pay dividends?

Prothena Corp. Public Ltd. Co does not currently pay dividends.

Where can I find PRTA SEC filings?

Official SEC filings for Prothena Corp. Public Ltd. Co (CIK: 0001559053) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PRTA's EPS?

Prothena Corp. Public Ltd. Co has a diluted EPS of $0.60.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is PRTA's fundamental grade?

Based on our AI fundamental analysis in May 2026, Prothena Corp. Public Ltd. Co has a C grade with 68% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is PRTA stock overvalued or undervalued?

Valuation metrics for PRTA: ROE of 10.5% (sector avg: 15%), net margin of 64.1% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is PRTA's AI grade for 2026?

Our dual AI analysis gives Prothena Corp. Public Ltd. Co a combined C grade for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is PRTA's free cash flow?

Prothena Corp. Public Ltd. Co's operating cash flow is $28.9M, with capital expenditures of $110.0K. FCF margin is 56.3%.

How does PRTA compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 64.1% (avg: 12%), ROE 10.5% (avg: 15%), current ratio 10.43 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 9, 2026 | Data as of: 2026-03-31 | Powered by Claude AI