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Pulse Biosciences, Inc.. (PLSE) Fundamental Analysis & AI Grade 2026

PLSE Nasdaq Surgical & Medical Instruments & Apparatus DE CIK: 0001625101
Updated This Month • Analysis: May 16, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
72% Confidence
N/A
C
72% Conf
Pending
Analysis scheduled

📊 PLSE Key Takeaways

Revenue: $401.0K
Net Margin: -4,633.7%
Free Cash Flow: $-14.6M
Current Ratio: 7.26x
Debt/Equity: 0.00x
EPS: $-1.50
AI Grade: C with 72% confidence
Pulse Biosciences, Inc.. (PLSE) receives a C fundamental grade with 72% confidence from our AI analysis based on SEC 10-K filings. With revenue of $401.0K, net profit margin of -4,633.7%, and return on equity (ROE) of -28.0%, Pulse Biosciences, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PLSE stock analysis for 2026.

Is Pulse Biosciences, Inc.. (PLSE) a Good Investment?

Claude

Pulse Biosciences exhibits severe fundamental weakness with $19.1M operating losses on only $401K revenue, indicating minimal commercial traction and unsustainable burn rate of $14.6M annually. While the $68.3M cash position and zero debt provide runway to continue operations for approximately 4-5 years, the company has yet to demonstrate a viable business model or path to profitability. Execution risk remains extremely high without evidence of significant revenue acceleration or operating leverage.

Pulse Biosciences, Inc.. Key Strengths (PLSE)

Claude
  • + Strong balance sheet with $68.3M cash and zero long-term debt
  • + Exceptional liquidity position with 7.26x current ratio providing financial flexibility
  • + Minimal capital intensity with only $33K capex allows focus on product development and commercialization

PLSE Stock Risks: Pulse Biosciences, Inc.. Investment Risks

Claude
  • ! Catastrophic operating losses of $19.1M against $401K revenue indicates fundamental business model failure or extremely early stage with minimal market validation
  • ! Negative operating cash flow of $14.6M annually will deplete cash runway within 4-5 years without achieving cash flow breakeven
  • ! Extreme negative profitability metrics across all measures (-4775.6% operating margin, -4633.7% net margin) demonstrate complete lack of current business viability

Key Metrics to Watch

Claude
  • * Revenue growth rate and trajectory toward meaningful commercial scale from $401K baseline
  • * Operating cash burn rate trend and timeline to cash flow positive operations
  • * Gross margins and operating expense ratios once revenue begins scaling materially
  • * Cash runway depletion timeline and need for additional capital raises
  • * Path to operating breakeven and positive net income through either revenue growth or cost reduction

Pulse Biosciences, Inc.. (PLSE) Financial Metrics & Key Ratios

Revenue
$401.0K
Net Income
$-18.6M
EPS (Diluted)
$-1.50
Free Cash Flow
$-14.6M
Total Assets
$81.6M
Cash Position
$68.3M

💡 AI Analyst Insight

Strong liquidity with a 7.26x current ratio provides a solid financial cushion.

PLSE Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -4,775.6%
Net Margin -4,633.7%
ROE -28.0%
ROA -22.8%
FCF Margin -3,647.9%

PLSE vs Healthcare Sector: How Pulse Biosciences, Inc.. Compares

How Pulse Biosciences, Inc.. compares to Healthcare sector averages

Net Margin
PLSE -4,633.7%
vs
Sector Avg 12.0%
PLSE Sector
ROE
PLSE -28.0%
vs
Sector Avg 15.0%
PLSE Sector
Current Ratio
PLSE 7.3x
vs
Sector Avg 2.0x
PLSE Sector
Debt/Equity
PLSE 0.0x
vs
Sector Avg 0.6x
PLSE Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Pulse Biosciences, Inc.. Stock Overvalued? PLSE Valuation Analysis 2026

Based on fundamental analysis, Pulse Biosciences, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-28.0%
Sector avg: 15%
Net Profit Margin
-4,633.7%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Pulse Biosciences, Inc.. Balance Sheet: PLSE Debt, Cash & Liquidity

Current Ratio
7.26x
Quick Ratio
7.24x
Debt/Equity
0.00x
Debt/Assets
18.8%
Interest Coverage
-30.35x
Long-term Debt
N/A

PLSE Revenue & Earnings Growth: 5-Year Financial Trend

PLSE 5-year financial data: Year 2021: Revenue $1.4M, Net Income -$47.0M, EPS N/A. Year 2022: Revenue $1.4M, Net Income -$49.9M, EPS $-2.14. Year 2023: Revenue $700.0K, Net Income -$58.5M, EPS $-1.72. Year 2024: Revenue $0, Net Income -$42.2M, EPS $-0.85. Year 2025: Revenue $350.0K, Net Income -$53.6M, EPS $-0.92.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Pulse Biosciences, Inc..'s revenue has declined by 75% over the 5-year period, indicating business contraction. The most recent EPS of $-0.92 indicates the company is currently unprofitable.

PLSE Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-3,647.9%
Free cash flow / Revenue

PLSE Quarterly Earnings & Performance

Quarterly financial performance data for Pulse Biosciences, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 N/A -$16.8M $-0.25
Q3 2025 N/A -$12.7M $-0.21
Q2 2025 N/A -$11.4M $-0.20
Q1 2025 N/A -$10.1M $-0.18
Q3 2024 N/A -$10.6M $-0.19
Q2 2024 N/A -$9.9M $-0.20
Q1 2024 N/A -$9.8M $-0.18
Q3 2023 N/A -$10.6M $-0.19

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Pulse Biosciences, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$14.6M
Cash generated from operations
Capital Expenditures
$33.0K
Investment in assets
Dividends
None
No dividend program

PLSE SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Pulse Biosciences, Inc.. (CIK: 0001625101)

📋 Recent SEC Filings

Date Form Document Action
May 14, 2026 10-Q plse20260331_10q.htm View →
May 11, 2026 4 xslF345X06/rdgdoc.xml View →
May 11, 2026 4 xslF345X06/rdgdoc.xml View →
May 11, 2026 DEF 14A plse20260324_def14a.htm View →
May 6, 2026 8-K plse20260505_8k.htm View →

Frequently Asked Questions about PLSE

What is the AI rating for PLSE?

Pulse Biosciences, Inc.. (PLSE) has an AI grade of C with 72% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PLSE's key strengths?

Claude: Strong balance sheet with $68.3M cash and zero long-term debt. Exceptional liquidity position with 7.26x current ratio providing financial flexibility.

What are the risks of investing in PLSE?

Claude: Catastrophic operating losses of $19.1M against $401K revenue indicates fundamental business model failure or extremely early stage with minimal market validation. Negative operating cash flow of $14.6M annually will deplete cash runway within 4-5 years without achieving cash flow breakeven.

What is PLSE's revenue and growth?

Pulse Biosciences, Inc.. reported revenue of $401.0K.

Does PLSE pay dividends?

Pulse Biosciences, Inc.. does not currently pay dividends.

Where can I find PLSE SEC filings?

Official SEC filings for Pulse Biosciences, Inc.. (CIK: 0001625101) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PLSE's EPS?

Pulse Biosciences, Inc.. has a diluted EPS of $-1.50.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is PLSE's fundamental grade?

Based on our AI fundamental analysis in May 2026, Pulse Biosciences, Inc.. has a C grade with 72% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is PLSE stock overvalued or undervalued?

Valuation metrics for PLSE: ROE of -28.0% (sector avg: 15%), net margin of -4,633.7% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is PLSE's AI grade for 2026?

Our dual AI analysis gives Pulse Biosciences, Inc.. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is PLSE's free cash flow?

Pulse Biosciences, Inc..'s operating cash flow is $-14.6M, with capital expenditures of $33.0K. FCF margin is -3,647.9%.

How does PLSE compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -4,633.7% (avg: 12%), ROE -28.0% (avg: 15%), current ratio 7.26 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 16, 2026 | Data as of: 2026-03-31 | Powered by Claude AI