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Pulse Biosciences, Inc.. (PLSE) Stock Fundamental Analysis & AI Rating 2026

PLSE Nasdaq Surgical & Medical Instruments & Apparatus DE CIK: 0001625101
Recently Updated • Analysis: Apr 14, 2026 • SEC Data: 2025-12-31
STRONG SELL
82% Conf
Pending
Analysis scheduled

📊 PLSE Key Takeaways

Revenue: $350.0K
Net Margin: -20,794.6%
Free Cash Flow: $-54.4M
Current Ratio: 10.53x
Debt/Equity: 0.00x
EPS: $-1.50
AI Rating: STRONG SELL with 82% confidence
Pulse Biosciences, Inc.. (PLSE) receives a STRONG SELL rating with 82% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $350.0K, net profit margin of -20,794.6%, and return on equity (ROE) of -90.2%, Pulse Biosciences, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PLSE stock analysis for 2026.

Is Pulse Biosciences, Inc.. (PLSE) a Good Investment?

Claude

Pulse Biosciences is a pre-commercial or very early-stage medical device company with only $350K in revenue against $76.9M in operating losses, indicating it has not yet achieved meaningful commercialization. While the company maintains a strong cash position of $80.7M with zero debt and excellent liquidity, the accelerating losses (down 35.8% YoY), massive cash burn of $54.1M annually, and absence of revenue traction suggest execution risk and a runway of approximately 18-24 months at current burn rate. Without demonstrated product-market fit or credible near-term commercialization pathway, the company presents a highly speculative, high-risk fundamental profile.

Why Buy Pulse Biosciences, Inc.. Stock? PLSE Key Strengths

Claude
  • + Strong cash position of $80.7M with no debt, providing 18-24 month runway
  • + Excellent liquidity metrics (current ratio 10.53x, quick ratio 10.51x)
  • + Operates in medical device sector with potential for high-margin products at scale
  • + Minimal liabilities ($13.9M) relative to equity base

PLSE Stock Risks: Pulse Biosciences, Inc.. Investment Risks

Claude
  • ! Pre-commercial or extremely early-stage revenue ($350K) with no evidence of business traction
  • ! Massive operating losses ($76.9M) accelerating YoY (-35.8% net income deterioration)
  • ! Negative operating cash flow of $54.1M annually indicates unsustainable burn rate
  • ! No visibility to near-term profitability or clear path to revenue growth
  • ! High execution risk typical of clinical-stage or development-stage medtech companies
  • ! Cash depletion risk if commercialization is delayed or unsuccessful

Key Metrics to Watch

Claude
  • * Quarterly revenue growth and path to meaningful commercialization
  • * Operating cash burn rate and cash runway remaining
  • * Clinical trial progress, regulatory approvals, and product launch timelines
  • * Gross margin achievement once products reach meaningful scale
  • * Insider buying/selling patterns as indicator of management confidence

Pulse Biosciences, Inc.. (PLSE) Financial Metrics & Key Ratios

Revenue
$350.0K
Net Income
$-72.8M
EPS (Diluted)
$-1.50
Free Cash Flow
$-54.4M
Total Assets
$94.5M
Cash Position
$80.7M

💡 AI Analyst Insight

Strong liquidity with a 10.53x current ratio provides a solid financial cushion.

PLSE Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -21,982.6%
Net Margin -20,794.6%
ROE -90.2%
ROA -77.0%
FCF Margin -15,553.4%

PLSE vs Healthcare Sector: How Pulse Biosciences, Inc.. Compares

How Pulse Biosciences, Inc.. compares to Healthcare sector averages

Net Margin
PLSE -20,794.6%
vs
Sector Avg 12.0%
PLSE Sector
ROE
PLSE -90.2%
vs
Sector Avg 15.0%
PLSE Sector
Current Ratio
PLSE 10.5x
vs
Sector Avg 2.0x
PLSE Sector
Debt/Equity
PLSE 0.0x
vs
Sector Avg 0.6x
PLSE Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Pulse Biosciences, Inc.. Stock Overvalued? PLSE Valuation Analysis 2026

Based on fundamental analysis, Pulse Biosciences, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-90.2%
Sector avg: 15%
Net Profit Margin
-20,794.6%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Pulse Biosciences, Inc.. Balance Sheet: PLSE Debt, Cash & Liquidity

Current Ratio
10.53x
Quick Ratio
10.51x
Debt/Equity
0.00x
Debt/Assets
14.7%
Interest Coverage
-121.93x
Long-term Debt
N/A

PLSE Revenue & Earnings Growth: 5-Year Financial Trend

PLSE 5-year financial data: Year 2021: Revenue $1.4M, Net Income -$47.0M, EPS N/A. Year 2022: Revenue $1.4M, Net Income -$49.9M, EPS $-2.14. Year 2023: Revenue $700.0K, Net Income -$58.5M, EPS $-1.72. Year 2024: Revenue $0, Net Income -$42.2M, EPS $-0.85. Year 2025: Revenue $350.0K, Net Income -$53.6M, EPS $-0.92.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Pulse Biosciences, Inc..'s revenue has declined by 75% over the 5-year period, indicating business contraction. The most recent EPS of $-0.92 indicates the company is currently unprofitable.

PLSE Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-15,553.4%
Free cash flow / Revenue

PLSE Quarterly Earnings & Performance

Quarterly financial performance data for Pulse Biosciences, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 N/A -$12.7M $-0.21
Q2 2025 N/A -$11.4M $-0.20
Q1 2025 N/A -$10.1M $-0.18
Q3 2024 N/A -$10.6M $-0.19
Q2 2024 N/A -$9.9M $-0.20
Q1 2024 N/A -$9.8M $-0.18
Q3 2023 N/A -$10.6M $-0.19
Q2 2023 N/A -$9.9M $-0.22

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Pulse Biosciences, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$54.1M
Cash generated from operations
Capital Expenditures
$315.0K
Investment in assets
Dividends
None
No dividend program

PLSE SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Pulse Biosciences, Inc.. (CIK: 0001625101)

📋 Recent SEC Filings

Date Form Document Action
Apr 9, 2026 8-K plse20260316_8k.htm View →
Apr 7, 2026 8-K plse20260406_8k.htm View →
Apr 3, 2026 4 xslF345X06/rdgdoc.xml View →
Mar 27, 2026 8-K plse20260327_8k.htm View →
Mar 17, 2026 8-K plse20260316c_8k.htm View →

Frequently Asked Questions about PLSE

What is the AI rating for PLSE?

Pulse Biosciences, Inc.. (PLSE) has an AI rating of STRONG SELL with 82% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PLSE's key strengths?

Claude: Strong cash position of $80.7M with no debt, providing 18-24 month runway. Excellent liquidity metrics (current ratio 10.53x, quick ratio 10.51x).

What are the risks of investing in PLSE?

Claude: Pre-commercial or extremely early-stage revenue ($350K) with no evidence of business traction. Massive operating losses ($76.9M) accelerating YoY (-35.8% net income deterioration).

What is PLSE's revenue and growth?

Pulse Biosciences, Inc.. reported revenue of $350.0K.

Does PLSE pay dividends?

Pulse Biosciences, Inc.. does not currently pay dividends.

Where can I find PLSE SEC filings?

Official SEC filings for Pulse Biosciences, Inc.. (CIK: 0001625101) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PLSE's EPS?

Pulse Biosciences, Inc.. has a diluted EPS of $-1.50.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is PLSE a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Pulse Biosciences, Inc.. has a STRONG SELL rating with 82% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is PLSE stock overvalued or undervalued?

Valuation metrics for PLSE: ROE of -90.2% (sector avg: 15%), net margin of -20,794.6% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy PLSE stock in 2026?

Our dual AI analysis gives Pulse Biosciences, Inc.. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is PLSE's free cash flow?

Pulse Biosciences, Inc..'s operating cash flow is $-54.1M, with capital expenditures of $315.0K. FCF margin is -15,553.4%.

How does PLSE compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -20,794.6% (avg: 12%), ROE -90.2% (avg: 15%), current ratio 10.53 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 14, 2026 | Data as of: 2025-12-31 | Powered by Claude AI