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Orasure Technologies Inc. (OSUR) Fundamental Analysis & AI Grade 2026

OSUR Nasdaq Surgical & Medical Instruments & Apparatus DE CIK: 0001116463
Updated This Month • Analysis: May 9, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
76% Confidence
AGREEMENT
D
78% Conf
C
74% Conf

📊 OSUR Key Takeaways

Revenue: $27.9M
Net Margin: -80.1%
Free Cash Flow: $-14.8M
Current Ratio: 5.46x
Debt/Equity: 0.00x
EPS: $-0.32
AI Grade: D with 78% confidence
Orasure Technologies Inc. (OSUR) receives a C fundamental grade with 76% confidence from our AI analysis based on SEC 10-K filings. With revenue of $27.9M, net profit margin of -80.1%, and return on equity (ROE) of -7.1%, Orasure Technologies Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete OSUR stock analysis for 2026.

Is Orasure Technologies Inc. (OSUR) a Good Investment?

Claude

OraSure faces severe operational distress with 38% YoY revenue decline and significant operating losses (-$23.3M), despite maintaining a strong balance sheet with $177M cash and zero debt. Negative operating cash flow (-$13.9M) and deteriorating cash burn indicate business challenges that will erode the equity cushion without a successful turnaround. The company's substantial liquidity provides runway but masks fundamental business deterioration that makes current operations unsustainable.

ChatGPT

Fundamentals have deteriorated sharply: revenue fell 38% YoY and the company posted deep operating and net losses with negative free cash flow. While the balance sheet is cash-rich, debt-free, and highly liquid, the core business is not generating profits or cash. Until revenue stabilizes and operating expenses are right-sized, the risk of continued cash burn remains high.

Orasure Technologies Inc. Key Strengths (OSUR)

Claude
  • + Strong balance sheet with $313.3M stockholders equity and zero debt
  • + Substantial cash reserves of $177.0M providing operational runway
  • + Excellent liquidity ratios (5.46x current ratio, 4.77x quick ratio) for financial flexibility
  • + Reasonable gross margins at 42.3% indicating underlying product value
ChatGPT
  • + Debt-free balance sheet with ~$199M cash and strong liquidity
  • + Healthy gross margin (~42%) suggesting viable unit economics if scaled properly
  • + Low capex needs provide flexibility to restructure

OSUR Stock Risks: Orasure Technologies Inc. Investment Risks

Claude
  • ! Severe revenue contraction of 38.1% YoY signals significant market or competitive headwinds in core business
  • ! Operating losses of $23.3M and negative operating cash flow of -$13.9M indicate inability to support current cost structure
  • ! Negative free cash flow of -$14.8M means equity is being consumed to fund operations unsustainably
  • ! Operating margin of -83.3% reflects fundamental unprofitability requiring restructuring or business model change
ChatGPT
  • ! Sustained revenue contraction undermining operating leverage
  • ! Persistent operating losses and negative FCF eroding cash runway
  • ! Regulatory or demand shifts in diagnostics impacting volumes and pricing

Key Metrics to Watch

Claude
  • * Quarterly revenue trend to determine if decline is stabilizing or accelerating further
  • * Operating cash flow trajectory and estimated cash burn runway at current losses
  • * Cost reduction initiatives and path to operating profitability
  • * Gross margin stability and evidence of successful product/market repositioning
ChatGPT
  • * Sequential revenue growth/stabilization
  • * Operating cash flow and cash burn runway

Orasure Technologies Inc. (OSUR) Financial Metrics & Key Ratios

Revenue
$27.9M
Net Income
$-22.4M
EPS (Diluted)
$-0.32
Free Cash Flow
$-14.8M
Total Assets
$379.2M
Cash Position
$177.0M

💡 AI Analyst Insight

Strong liquidity with a 5.46x current ratio provides a solid financial cushion.

OSUR Profit Margin, ROE & Profitability Analysis

Gross Margin 42.3%
Operating Margin -83.3%
Net Margin -80.1%
ROE -7.1%
ROA -5.9%
FCF Margin -53.0%

OSUR vs Healthcare Sector: How Orasure Technologies Inc. Compares

How Orasure Technologies Inc. compares to Healthcare sector averages

Net Margin
OSUR -80.1%
vs
Sector Avg 12.0%
OSUR Sector
ROE
OSUR -7.1%
vs
Sector Avg 15.0%
OSUR Sector
Current Ratio
OSUR 5.5x
vs
Sector Avg 2.0x
OSUR Sector
Debt/Equity
OSUR 0.0x
vs
Sector Avg 0.6x
OSUR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Orasure Technologies Inc. Stock Overvalued? OSUR Valuation Analysis 2026

Based on fundamental analysis, Orasure Technologies Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-7.1%
Sector avg: 15%
Net Profit Margin
-80.1%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Orasure Technologies Inc. Balance Sheet: OSUR Debt, Cash & Liquidity

Current Ratio
5.46x
Quick Ratio
4.77x
Debt/Equity
0.00x
Debt/Assets
17.4%
Interest Coverage
-135.28x
Long-term Debt
N/A

OSUR Revenue & Earnings Growth: 5-Year Financial Trend

OSUR 5-year financial data: Year 2021: Revenue $233.7M, Net Income $16.7M, EPS $0.27. Year 2022: Revenue $387.5M, Net Income -$14.9M, EPS $0.22. Year 2023: Revenue $405.5M, Net Income -$23.0M, EPS $-0.32. Year 2024: Revenue $405.5M, Net Income -$17.1M, EPS $-0.24. Year 2025: Revenue $405.5M, Net Income $53.7M, EPS $0.72.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Orasure Technologies Inc.'s revenue has grown significantly by 74% over the 5-year period, indicating strong business expansion. The most recent EPS of $0.72 reflects profitable operations.

OSUR Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-53.0%
Free cash flow / Revenue

OSUR Quarterly Earnings & Performance

Quarterly financial performance data for Orasure Technologies Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $27.9M -$16.0M $-0.21
Q3 2025 $27.1M -$615.0K $-0.06
Q2 2025 $31.2M -$615.0K $-0.01
Q1 2025 $29.9M -$3.6M $-0.05
Q3 2024 $39.9M -$615.0K $-0.06
Q2 2024 $54.3M -$615.0K $-0.01
Q1 2024 $54.1M -$3.6M $-0.05
Q3 2023 $89.2M -$4.8M $0.08

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Orasure Technologies Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$13.9M
Cash generated from operations
Stock Buybacks
$5.0M
Shares repurchased (TTM)
Capital Expenditures
$913.0K
Investment in assets
Dividends
None
No dividend program

OSUR SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Orasure Technologies Inc. (CIK: 0001116463)

📋 Recent SEC Filings

Date Form Document Action
May 14, 2026 4 xslF345X06/form4.xml View →
May 14, 2026 4 xslF345X06/form4.xml View →
May 14, 2026 4 xslF345X06/form4.xml View →
May 14, 2026 4 xslF345X06/form4.xml View →
May 14, 2026 4 xslF345X06/form4.xml View →

Frequently Asked Questions about OSUR

What is the AI rating for OSUR?

Orasure Technologies Inc. (OSUR) has a Combined AI Grade of C from Claude (D) and ChatGPT (C) with 76% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are OSUR's key strengths?

Claude: Strong balance sheet with $313.3M stockholders equity and zero debt. Substantial cash reserves of $177.0M providing operational runway. ChatGPT: Debt-free balance sheet with ~$199M cash and strong liquidity. Healthy gross margin (~42%) suggesting viable unit economics if scaled properly.

What are the risks of investing in OSUR?

Claude: Severe revenue contraction of 38.1% YoY signals significant market or competitive headwinds in core business. Operating losses of $23.3M and negative operating cash flow of -$13.9M indicate inability to support current cost structure. ChatGPT: Sustained revenue contraction undermining operating leverage. Persistent operating losses and negative FCF eroding cash runway.

What is OSUR's revenue and growth?

Orasure Technologies Inc. reported revenue of $27.9M.

Does OSUR pay dividends?

Orasure Technologies Inc. does not currently pay dividends.

Where can I find OSUR SEC filings?

Official SEC filings for Orasure Technologies Inc. (CIK: 0001116463) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is OSUR's EPS?

Orasure Technologies Inc. has a diluted EPS of $-0.32.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is OSUR's fundamental grade?

Based on our AI fundamental analysis in May 2026, Orasure Technologies Inc. has a C grade with 76% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is OSUR stock overvalued or undervalued?

Valuation metrics for OSUR: ROE of -7.1% (sector avg: 15%), net margin of -80.1% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is OSUR's AI grade for 2026?

Our dual AI analysis gives Orasure Technologies Inc. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is OSUR's free cash flow?

Orasure Technologies Inc.'s operating cash flow is $-13.9M, with capital expenditures of $913.0K. FCF margin is -53.0%.

How does OSUR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -80.1% (avg: 12%), ROE -7.1% (avg: 15%), current ratio 5.46 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 9, 2026 | Data as of: 2026-03-31 | Powered by Claude AI