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Heron Therapeutics, Inc.. /DE/ (HRTX) Stock Fundamental Analysis & AI Rating 2026

HRTX Nasdaq Pharmaceutical Preparations DE CIK: 0000818033
Updated This Month • Analysis: May 12, 2026 • SEC Data: 2026-03-31
Combined AI Rating
SELL
70% Confidence
STRONG AGREEMENT
SELL
75% Conf
SELL
66% Conf

📊 HRTX Key Takeaways

Revenue: $34.7M
Net Margin: -23.4%
Free Cash Flow: $-1.9M
Current Ratio: 2.53x
Debt/Equity: 0.00x
EPS: $-0.04
AI Rating: SELL with 75% confidence
Heron Therapeutics, Inc.. /DE/ (HRTX) receives a SELL rating with 70% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $34.7M, net profit margin of -23.4%, and return on equity (ROE) of -88.8%, Heron Therapeutics, Inc.. /DE/ demonstrates mixed fundamentals in the Healthcare sector. Below is our complete HRTX stock analysis for 2026.

Is Heron Therapeutics, Inc.. /DE/ (HRTX) a Good Investment?

Claude

Heron Therapeutics is an early-stage pharmaceutical company with a strong gross margin (69.4%) but deteriorating profitability, with net income declining 48.7% YoY despite modest 7.4% revenue growth. The company is burning cash operationally (-$1.5M) and has minimal shareholders' equity ($9.1M) relative to total liabilities ($237.1M), creating unsustainable financial dynamics. Without near-term profitability or significant revenue acceleration, the company faces mounting dilution risk.

ChatGPT

High 73% gross margin and modest 7% revenue growth show product traction and improving operating leverage near breakeven. Yet persistent net losses, negative free cash flow, and a razor‑thin equity base create elevated financing/dilution risk unless operating cash flow turns sustainably positive soon.

Why Buy Heron Therapeutics, Inc.. /DE/ Stock? HRTX Key Strengths

Claude
  • + Strong gross margin of 69.4% indicates product pricing power and low manufacturing costs
  • + Positive revenue growth of 7.4% YoY demonstrates some market traction
  • + Solid short-term liquidity with current ratio of 2.53x and $26.1M cash position
ChatGPT
  • + Strong gross margin indicating pricing power
  • + Operating margin near breakeven suggests improving cost control
  • + Solid near-term liquidity with a 2.5x current ratio

HRTX Stock Risks: Heron Therapeutics, Inc.. /DE/ Investment Risks

Claude
  • ! Deteriorating profitability with net income declining 48.7% YoY despite revenue growth
  • ! Negative operating cash flow of -$1.5M indicates business is not operationally sustainable
  • ! Critically low shareholders' equity ($9.1M) relative to liabilities ($237.1M) creates severe financial distress risk
  • ! Operating losses of -$4.8M and negative operating margin of -13.7% show lack of near-term path to profitability
ChatGPT
  • ! Negative free cash flow and OCF imply ongoing cash burn
  • ! Very thin equity and severe negative ROE highlight balance-sheet fragility
  • ! Negative interest coverage and high liabilities relative to assets raise solvency risk

Key Metrics to Watch

Claude
  • * Operating cash flow trajectory toward breakeven
  • * Revenue acceleration rate and sales traction metrics
  • * Operating margin improvement and path to operating profitability
  • * Cash burn rate and estimated runway
  • * Shareholder dilution from equity financing rounds
ChatGPT
  • * Operating cash flow and cash runway (cash/FCF)
  • * Operating margin progression toward sustained profitability

Heron Therapeutics, Inc.. /DE/ (HRTX) Financial Metrics & Key Ratios

Revenue
$34.7M
Net Income
$-8.1M
EPS (Diluted)
$-0.04
Free Cash Flow
$-1.9M
Total Assets
$246.2M
Cash Position
$26.1M

💡 AI Analyst Insight

Strong liquidity with a 2.53x current ratio provides a solid financial cushion.

HRTX Profit Margin, ROE & Profitability Analysis

Gross Margin 69.4%
Operating Margin -13.7%
Net Margin -23.4%
ROE -88.8%
ROA -3.3%
FCF Margin -5.6%

HRTX vs Healthcare Sector: How Heron Therapeutics, Inc.. /DE/ Compares

How Heron Therapeutics, Inc.. /DE/ compares to Healthcare sector averages

Net Margin
HRTX -23.4%
vs
Sector Avg 12.0%
HRTX Sector
ROE
HRTX -88.8%
vs
Sector Avg 15.0%
HRTX Sector
Current Ratio
HRTX 2.5x
vs
Sector Avg 2.0x
HRTX Sector
Debt/Equity
HRTX 0.0x
vs
Sector Avg 0.6x
HRTX Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Heron Therapeutics, Inc.. /DE/ Stock Overvalued? HRTX Valuation Analysis 2026

Based on fundamental analysis, Heron Therapeutics, Inc.. /DE/ has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-88.8%
Sector avg: 15%
Net Profit Margin
-23.4%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Heron Therapeutics, Inc.. /DE/ Balance Sheet: HRTX Debt, Cash & Liquidity

Current Ratio
2.53x
Quick Ratio
1.51x
Debt/Equity
0.00x
Debt/Assets
96.3%
Interest Coverage
-1.23x
Long-term Debt
N/A

HRTX Revenue & Earnings Growth: 5-Year Financial Trend

HRTX 5-year financial data: Year 2021: Revenue $146.0M, Net Income -$204.7M, EPS N/A. Year 2022: Revenue $107.7M, Net Income -$220.7M, EPS $-2.24. Year 2023: Revenue $127.0M, Net Income -$182.0M, EPS $-1.67. Year 2024: Revenue $144.3M, Net Income -$182.0M, EPS $-1.67. Year 2025: Revenue $154.9M, Net Income -$110.6M, EPS $-0.80.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Heron Therapeutics, Inc.. /DE/'s revenue has shown modest growth of 6% over the 5-year period. The most recent EPS of $-0.80 indicates the company is currently unprofitable.

HRTX Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-5.6%
Free cash flow / Revenue

HRTX Quarterly Earnings & Performance

Quarterly financial performance data for Heron Therapeutics, Inc.. /DE/ including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $34.7M $2.6M $0.01
Q3 2025 $32.8M -$2.4M $-0.03
Q2 2025 $36.0M $254.0K $0.00
Q1 2025 $34.7M $2.6M $0.01
Q3 2024 $31.4M -$3.2M $-0.03
Q2 2024 $31.8M -$3.2M $-0.06
Q1 2024 $29.6M -$3.2M $-0.02
Q3 2023 $26.6M -$25.0M $-0.17

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Heron Therapeutics, Inc.. /DE/ Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$1.5M
Cash generated from operations
Capital Expenditures
$391.0K
Investment in assets
Dividends
None
No dividend program

HRTX SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Heron Therapeutics, Inc.. /DE/ (CIK: 0000818033)

📋 Recent SEC Filings

Date Form Document Action
May 11, 2026 10-Q hrtx-20260331.htm View →
May 11, 2026 8-K hrtx-20260511.htm View →
May 7, 2026 4 xslF345X06/ownership.xml View →
May 4, 2026 4 xslF345X06/ownership.xml View →
May 4, 2026 4 xslF345X06/ownership.xml View →

Frequently Asked Questions about HRTX

What is the AI rating for HRTX?

Heron Therapeutics, Inc.. /DE/ (HRTX) has a Combined AI Rating of SELL from Claude (SELL) and ChatGPT (SELL) with 70% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are HRTX's key strengths?

Claude: Strong gross margin of 69.4% indicates product pricing power and low manufacturing costs. Positive revenue growth of 7.4% YoY demonstrates some market traction. ChatGPT: Strong gross margin indicating pricing power. Operating margin near breakeven suggests improving cost control.

What are the risks of investing in HRTX?

Claude: Deteriorating profitability with net income declining 48.7% YoY despite revenue growth. Negative operating cash flow of -$1.5M indicates business is not operationally sustainable. ChatGPT: Negative free cash flow and OCF imply ongoing cash burn. Very thin equity and severe negative ROE highlight balance-sheet fragility.

What is HRTX's revenue and growth?

Heron Therapeutics, Inc.. /DE/ reported revenue of $34.7M.

Does HRTX pay dividends?

Heron Therapeutics, Inc.. /DE/ does not currently pay dividends.

Where can I find HRTX SEC filings?

Official SEC filings for Heron Therapeutics, Inc.. /DE/ (CIK: 0000818033) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is HRTX's EPS?

Heron Therapeutics, Inc.. /DE/ has a diluted EPS of $-0.04.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is HRTX a good stock to buy right now?

Based on our AI fundamental analysis in May 2026, Heron Therapeutics, Inc.. /DE/ has a SELL rating with 70% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is HRTX stock overvalued or undervalued?

Valuation metrics for HRTX: ROE of -88.8% (sector avg: 15%), net margin of -23.4% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy HRTX stock in 2026?

Our dual AI analysis gives Heron Therapeutics, Inc.. /DE/ a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is HRTX's free cash flow?

Heron Therapeutics, Inc.. /DE/'s operating cash flow is $-1.5M, with capital expenditures of $391.0K. FCF margin is -5.6%.

How does HRTX compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -23.4% (avg: 12%), ROE -88.8% (avg: 15%), current ratio 2.53 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 12, 2026 | Data as of: 2026-03-31 | Powered by Claude AI