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CBIO Stock Analysis - CRESCENT BIOPHARMA, INC. AI Rating

CBIO Nasdaq Pharmaceutical Preparations E9 CIK: 0001253689
Recently Updated • Analysis: Mar 21, 2026 • SEC Data: 2025-12-31
AI Rating
STRONG SELL
92% Confidence

📊 CBIO Key Takeaways

Revenue: $10.8M
Net Margin: -1,419.6%
Free Cash Flow: $-72.5M
Current Ratio: 6.56x
Debt/Equity: 0.00x
EPS: $-0.59
AI Rating: STRONG SELL with 92% confidence

Investment Thesis

Crescent BioPharma is a pre-revenue biotech company with severe operational losses and negative cash flow despite having substantial cash reserves. The company is burning capital at an unsustainable rate with operating expenses far exceeding minimal revenue, indicating immature or failed drug development programs with no clear path to profitability.

CBIO Strengths

  • + Strong liquidity position with $213.2M in cash and 6.56x current ratio, providing runway for operations
  • + Minimal debt burden with 0.00x debt-to-equity ratio, reducing financial distress risk
  • + Substantial equity cushion of $203.0M providing balance sheet stability

CBIO Risks

  • ! Massive operating losses of -$152.6M with -1407.5% operating margin indicating failed or delayed drug development
  • ! Severe negative cash flow of -$72.5M free cash flow annually will deplete cash reserves in ~3 years at current burn rate
  • ! Near-zero revenue of $10.8M with no gross profit metrics suggests no viable commercial products or market traction
  • ! Negative ROE of -75.8% and ROA of -64.1% demonstrate value destruction and inefficient capital deployment
  • ! No insider buying activity in 90 days suggests lack of management confidence

Key Metrics to Watch

CBIO Financial Metrics

Revenue
$10.8M
Net Income
$-153.9M
EPS (Diluted)
$-0.59
Free Cash Flow
$-72.5M
Total Assets
$240.3M
Cash Position
$213.2M

💡 AI Analyst Insight

Strong liquidity with a 6.56x current ratio provides a solid financial cushion.

CBIO Profitability Ratios

Gross Margin N/A
Operating Margin -1,407.5%
Net Margin -1,419.6%
ROE -75.8%
ROA -64.1%
FCF Margin -668.1%

CBIO vs Healthcare Sector

How CRESCENT BIOPHARMA, INC. compares to Healthcare sector averages

Net Margin
CBIO -1,419.6%
vs
Sector Avg 12.0%
CBIO Sector
ROE
CBIO -75.8%
vs
Sector Avg 15.0%
CBIO Sector
Current Ratio
CBIO 6.6x
vs
Sector Avg 2.0x
CBIO Sector
Debt/Equity
CBIO 0.0x
vs
Sector Avg 0.6x
CBIO Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

CBIO Balance Sheet & Liquidity

Current Ratio
6.56x
Quick Ratio
6.56x
Debt/Equity
0.00x
Debt/Assets
15.5%
Interest Coverage
N/A
Long-term Debt
N/A

CBIO 5-Year Financial Trend

CBIO 5-year financial data: Year 2025: Revenue $10.8M, Net Income -$17.9M, EPS N/A.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: CRESCENT BIOPHARMA, INC.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-0.58 indicates the company is currently unprofitable.

CBIO Growth Metrics (YoY)

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-668.1%
Free cash flow / Revenue

CBIO Quarterly Performance

Quarterly financial performance data for CRESCENT BIOPHARMA, INC. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2023 $75.0K -$8.3M $-0.14
Q2 2023 $75.0K -$8.3M $-0.13
Q3 2022 $75.0K -$8.5M $-0.16
Q2 2022 $142 -$13.3M $-0.25
Q1 2022 $1.1M -$14.3M $-0.28
Q3 2021 $86.6K -$7.7M N/A
Q2 2021 $142 -$7.7M N/A
Q1 2021 $1.1M -$7.7M N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

CBIO Capital Allocation

Operating Cash Flow
-$71.5M
Cash generated from operations
Capital Expenditures
$919.0K
Investment in assets
Dividends
None
No dividend program

CBIO SEC Filings

Access official SEC EDGAR filings for CRESCENT BIOPHARMA, INC. (CIK: 0001253689)

📋 Recent SEC Filings

Date Form Document Action
Feb 26, 2026 8-K cbio-20260226.htm View →
Feb 26, 2026 10-K cbio-20251231.htm View →
Jan 7, 2026 S-1 cbio-20260107.htm View →
Dec 17, 2025 4 xslF345X05/wk-form4_1766008146.xml View →
Dec 17, 2025 4 xslF345X05/wk-form4_1766008052.xml View →

Frequently Asked Questions about CBIO

What is the AI rating for CBIO?

CRESCENT BIOPHARMA, INC. (CBIO) has an AI rating of STRONG SELL with 92% confidence, based on fundamental analysis of SEC EDGAR filings.

What are CBIO's key strengths?

Strong liquidity position with $213.2M in cash and 6.56x current ratio, providing runway for operations. Minimal debt burden with 0.00x debt-to-equity ratio, reducing financial distress risk.

What are the risks of investing in CBIO?

Massive operating losses of -$152.6M with -1407.5% operating margin indicating failed or delayed drug development. Severe negative cash flow of -$72.5M free cash flow annually will deplete cash reserves in ~3 years at current burn rate.

What is CBIO's revenue and growth?

CRESCENT BIOPHARMA, INC. reported revenue of $10.8M.

Does CBIO pay dividends?

CRESCENT BIOPHARMA, INC. does not currently pay dividends.

Where can I find CBIO SEC filings?

Official SEC filings for CRESCENT BIOPHARMA, INC. (CIK: 0001253689) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CBIO's EPS?

CRESCENT BIOPHARMA, INC. has a diluted EPS of $-0.59.

How is the AI analysis conducted?

Our AI (Claude) analyzes publicly available SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports to evaluate financial health, profitability ratios, balance sheet strength, and growth metrics.

Disclaimer: This analysis is generated by Claude AI based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 21, 2026 | Data as of: 2025-12-31 | Powered by Claude AI