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BCYC Stock Analysis - BICYCLE THERAPEUTICS PLC AI Rating

BCYC Nasdaq Pharmaceutical Preparations X0 CIK: 0001761612
Recently Updated • Analysis: Mar 20, 2026 • SEC Data: 2025-12-31
AI Rating
SELL
85% Confidence

📊 BCYC Key Takeaways

Revenue: $72.6M
Net Margin: -301.7%
Free Cash Flow: $-252.0M
Current Ratio: 11.98x
Debt/Equity: 0.05x
EPS: $-3.16
AI Rating: SELL with 85% confidence

Investment Thesis

Bicycle Therapeutics is a pre-commercial pharmaceutical company with strong cash position ($628.1M) supporting runway, but demonstrates severe unprofitability with -$252.0M free cash flow burn and -301.7% net margin. While 105.8% revenue growth is encouraging, the company is consuming cash rapidly with operating losses of -$247.1M, raising questions about path to profitability and capital efficiency.

BCYC Strengths

  • + Exceptional liquidity with $628.1M cash and 11.98x current ratio providing substantial runway
  • + Strong revenue growth of 105.8% YoY demonstrating commercial traction
  • + Minimal leverage with 0.05x debt-to-equity ratio and only $30.9M long-term debt
  • + 16 Form 4 insider filings in last 90 days suggest active management engagement

BCYC Risks

  • ! Massive cash burn of $252.0M FCF with -347.2% FCF margin indicating unsustainable trajectory
  • ! Operating losses of -$247.1M far exceed revenue generation, showing negative unit economics
  • ! Negative interest coverage of -300.9x means company cannot service debt from operations
  • ! Revenue growth insufficient to offset operating losses; burn rate suggests 2-3 years of cash runway at current pace
  • ! Typical biotech R&D model with high upfront costs, but sustained -$249.7M operating cash burn indicates commercialization challenges

Key Metrics to Watch

BCYC Financial Metrics

Revenue
$72.6M
Net Income
$-219.0M
EPS (Diluted)
$-3.16
Free Cash Flow
$-252.0M
Total Assets
$717.6M
Cash Position
$628.1M

💡 AI Analyst Insight

Strong liquidity with a 11.98x current ratio provides a solid financial cushion.

BCYC Profitability Ratios

Gross Margin N/A
Operating Margin -340.4%
Net Margin -301.7%
ROE -35.9%
ROA -30.5%
FCF Margin -347.2%

BCYC vs Healthcare Sector

How BICYCLE THERAPEUTICS PLC compares to Healthcare sector averages

Net Margin
BCYC -301.7%
vs
Sector Avg 12.0%
BCYC Sector
ROE
BCYC -35.9%
vs
Sector Avg 15.0%
BCYC Sector
Current Ratio
BCYC 12.0x
vs
Sector Avg 2.0x
BCYC Sector
Debt/Equity
BCYC 0.1x
vs
Sector Avg 0.6x
BCYC Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

BCYC Balance Sheet & Liquidity

Current Ratio
11.98x
Quick Ratio
11.98x
Debt/Equity
0.05x
Debt/Assets
15.0%
Interest Coverage
-300.93x
Long-term Debt
$30.9M

BCYC 5-Year Financial Trend

BCYC 5-year financial data: Year 2021: Revenue $13.8M, Net Income -$30.6M, EPS $-2.77. Year 2022: Revenue $14.5M, Net Income -$51.0M, EPS $-2.66. Year 2023: Revenue $27.0M, Net Income -$66.8M, EPS $-2.67. Year 2024: Revenue $35.3M, Net Income -$112.7M, EPS $-3.80. Year 2025: Revenue $72.6M, Net Income -$180.7M, EPS $-5.08.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: BICYCLE THERAPEUTICS PLC's revenue has grown significantly by 426% over the 5-year period, indicating strong business expansion. The most recent EPS of $-5.08 indicates the company is currently unprofitable.

BCYC Growth Metrics (YoY)

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-347.2%
Free cash flow / Revenue

BCYC Quarterly Performance

Quarterly financial performance data for BICYCLE THERAPEUTICS PLC including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $2.7M -$26.6M $-0.74
Q2 2025 $2.9M -$26.6M $-0.77
Q1 2025 $10.0M -$26.6M $-0.62
Q3 2024 $2.7M -$26.6M $-0.74
Q2 2024 $9.4M -$26.6M $-0.77
Q1 2024 $4.9M -$26.6M $-0.62
Q3 2023 $3.0M -$26.8M $-0.96
Q2 2023 $4.4M -$26.8M $-0.90

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

BCYC Capital Allocation

Operating Cash Flow
-$249.7M
Cash generated from operations
Capital Expenditures
$2.4M
Investment in assets
Dividends
None
No dividend program

BCYC SEC Filings

Access official SEC EDGAR filings for BICYCLE THERAPEUTICS PLC (CIK: 0001761612)

📋 Recent SEC Filings

Date Form Document Action
Mar 17, 2026 10-K bcyc-20251231x10k.htm View →
Mar 17, 2026 8-K tm268887d1_8k.htm View →
Feb 4, 2026 4 xslF345X05/form4-02052026_120235.xml View →
Feb 3, 2026 8-K tm264844d1_8k.htm View →
Jan 12, 2026 8-K tm262874d1_8k.htm View →

Frequently Asked Questions about BCYC

What is the AI rating for BCYC?

BICYCLE THERAPEUTICS PLC (BCYC) has an AI rating of SELL with 85% confidence, based on fundamental analysis of SEC EDGAR filings.

What are BCYC's key strengths?

Exceptional liquidity with $628.1M cash and 11.98x current ratio providing substantial runway. Strong revenue growth of 105.8% YoY demonstrating commercial traction.

What are the risks of investing in BCYC?

Massive cash burn of $252.0M FCF with -347.2% FCF margin indicating unsustainable trajectory. Operating losses of -$247.1M far exceed revenue generation, showing negative unit economics.

What is BCYC's revenue and growth?

BICYCLE THERAPEUTICS PLC reported revenue of $72.6M.

Does BCYC pay dividends?

BICYCLE THERAPEUTICS PLC does not currently pay dividends.

Where can I find BCYC SEC filings?

Official SEC filings for BICYCLE THERAPEUTICS PLC (CIK: 0001761612) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is BCYC's EPS?

BICYCLE THERAPEUTICS PLC has a diluted EPS of $-3.16.

How is the AI analysis conducted?

Our AI (Claude) analyzes publicly available SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports to evaluate financial health, profitability ratios, balance sheet strength, and growth metrics.

Disclaimer: This analysis is generated by Claude AI based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 20, 2026 | Data as of: 2025-12-31 | Powered by Claude AI