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Tyra Biosciences, Inc. (TYRA) Stock Fundamental Analysis & AI Rating 2026

TYRA Nasdaq Pharmaceutical Preparations DE CIK: 0001863127
Recently Updated • Analysis: Apr 18, 2026 • SEC Data: 2025-12-31
SELL
72% Conf
Pending
Analysis scheduled

📊 TYRA Key Takeaways

Revenue: N/A
Net Margin: N/A
Free Cash Flow: $-95.3M
Current Ratio: 14.67x
Debt/Equity: 0.00x
EPS: $-2.01
AI Rating: SELL with 72% confidence
Tyra Biosciences, Inc. (TYRA) receives a SELL rating with 72% confidence from our AI fundamental analysis based on SEC 10-K filings., and return on equity (ROE) of -46.3% Below is our complete TYRA stock analysis for 2026.

Is Tyra Biosciences, Inc. (TYRA) a Good Investment?

Claude

Tyra Biosciences is a pre-commercial stage biotech company with no reported revenue, burning $95M annually in operating cash flow, and deteriorating losses (down 38.7% YoY). While the balance sheet shows adequate equity and liquidity, the company faces severe execution risk with less than one year of cash runway at current burn rates and absolute dependence on successful drug development and commercialization.

Why Buy Tyra Biosciences, Inc. Stock? TYRA Key Strengths

Claude
  • + Strong balance sheet with $259.2M stockholders equity and minimal debt (0.00x D/E ratio)
  • + Adequate cash position of $77.4M with exceptional liquidity ratios (14.67x current ratio)
  • + No near-term debt obligations allowing flexibility for capital deployment

TYRA Stock Risks: Tyra Biosciences, Inc. Investment Risks

Claude
  • ! No revenue generation indicates pre-commercial stage with significant development risk
  • ! Operating losses expanding YoY (38.7% deterioration in net income), signaling worsening cash burn
  • ! Cash runway of approximately 9-10 months at current $95.1M annual operating cash burn rate
  • ! Requires successful Phase III trials, regulatory approval, and market adoption to achieve profitability
  • ! Biotech dependency on single or limited drug pipeline with binary success/failure outcomes

Key Metrics to Watch

Claude
  • * Operating cash flow trend and runway extension through capital raises or cost reduction
  • * Clinical trial progress updates and regulatory milestones for lead drug candidates
  • * Quarterly cash burn rate and changes in cash reserves
  • * Patent expirations and competitive pipeline developments in target therapeutic areas

Tyra Biosciences, Inc. (TYRA) Financial Metrics & Key Ratios

Revenue
N/A
Net Income
$-119.9M
EPS (Diluted)
$-2.01
Free Cash Flow
$-95.3M
Total Assets
$282.6M
Cash Position
$77.4M

💡 AI Analyst Insight

Strong liquidity with a 14.67x current ratio provides a solid financial cushion.

TYRA Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -46.3%
ROA -42.4%
FCF Margin N/A

TYRA vs Healthcare Sector: How Tyra Biosciences, Inc. Compares

How Tyra Biosciences, Inc. compares to Healthcare sector averages

Net Margin
TYRA 0.0%
vs
Sector Avg 12.0%
TYRA Sector
ROE
TYRA -46.3%
vs
Sector Avg 15.0%
TYRA Sector
Current Ratio
TYRA 14.7x
vs
Sector Avg 2.0x
TYRA Sector
Debt/Equity
TYRA 0.0x
vs
Sector Avg 0.6x
TYRA Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Tyra Biosciences, Inc. Stock Overvalued? TYRA Valuation Analysis 2026

Based on fundamental analysis, Tyra Biosciences, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-46.3%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Tyra Biosciences, Inc. Balance Sheet: TYRA Debt, Cash & Liquidity

Current Ratio
14.67x
Quick Ratio
14.67x
Debt/Equity
0.00x
Debt/Assets
8.3%
Interest Coverage
N/A
Long-term Debt
N/A

TYRA Revenue & Earnings Growth: 5-Year Financial Trend

TYRA 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Tyra Biosciences, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-1.51 indicates the company is currently unprofitable.

TYRA Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

Tyra Biosciences, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$95.1M
Cash generated from operations
Capital Expenditures
$141.0K
Investment in assets
Dividends
None
No dividend program

TYRA SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Tyra Biosciences, Inc. (CIK: 0001863127)

📋 Recent SEC Filings

Date Form Document Action
Apr 17, 2026 DEF 14A d33035ddef14a.htm View →
Apr 17, 2026 8-K d17006d8k.htm View →
Apr 2, 2026 8-K d136343d8k.htm View →
Mar 27, 2026 4 xslF345X06/ownership.xml View →
Mar 17, 2026 4 xslF345X05/ownership.xml View →

Frequently Asked Questions about TYRA

What is the AI rating for TYRA?

Tyra Biosciences, Inc. (TYRA) has an AI rating of SELL with 72% confidence, based on fundamental analysis of SEC EDGAR filings.

What are TYRA's key strengths?

Claude: Strong balance sheet with $259.2M stockholders equity and minimal debt (0.00x D/E ratio). Adequate cash position of $77.4M with exceptional liquidity ratios (14.67x current ratio).

What are the risks of investing in TYRA?

Claude: No revenue generation indicates pre-commercial stage with significant development risk. Operating losses expanding YoY (38.7% deterioration in net income), signaling worsening cash burn.

What is TYRA's revenue and growth?

Tyra Biosciences, Inc. reported revenue of N/A.

Does TYRA pay dividends?

Tyra Biosciences, Inc. does not currently pay dividends.

Where can I find TYRA SEC filings?

Official SEC filings for Tyra Biosciences, Inc. (CIK: 0001863127) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is TYRA's EPS?

Tyra Biosciences, Inc. has a diluted EPS of $-2.01.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is TYRA a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Tyra Biosciences, Inc. has a SELL rating with 72% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is TYRA stock overvalued or undervalued?

Valuation metrics for TYRA: ROE of -46.3% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy TYRA stock in 2026?

Our dual AI analysis gives Tyra Biosciences, Inc. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is TYRA's free cash flow?

Tyra Biosciences, Inc.'s operating cash flow is $-95.1M, with capital expenditures of $141.0K.

How does TYRA compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -46.3% (avg: 15%), current ratio 14.67 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 18, 2026 | Data as of: 2025-12-31 | Powered by Claude AI