← Back to All US Stocks

Synlogic, Inc.. (SYBX) Stock Fundamental Analysis & AI Rating 2026

SYBX OTC Pharmaceutical Preparations DE CIK: 0001527599
Recently Updated • Analysis: Apr 17, 2026 • SEC Data: 2025-12-31
STRONG SELL
35% Conf
Pending
Analysis scheduled

📊 SYBX Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-4.4M
Current Ratio: 4.30x
Debt/Equity: 0.00x
EPS: $-0.08
AI Rating: STRONG SELL with 35% confidence
Synlogic, Inc.. (SYBX) receives a STRONG SELL rating with 35% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -8.5%, Synlogic, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete SYBX stock analysis for 2026.

Is Synlogic, Inc.. (SYBX) a Good Investment?

Claude

SYNLOGIC is a pre-revenue biopharmaceutical company with zero commercial product sales, negative operating cash flow of -4.4M, and approximately 3-4 quarters of remaining cash runway at current burn rates. While the company maintains a strong balance sheet with 14.7M in cash and no debt, the lack of revenue, ongoing losses, and absence of insider buying activity indicate significant fundamental weakness and uncertainty regarding path to profitability.

Why Buy Synlogic, Inc.. Stock? SYBX Key Strengths

Claude
  • + Strong liquidity position with 4.30x current ratio and 14.7M cash on hand
  • + Zero debt burden with 0.00x Debt/Equity ratio
  • + Stable equity base of 11.9M with low liability burden of 1.4M

SYBX Stock Risks: Synlogic, Inc.. Investment Risks

Claude
  • ! Zero revenue with 100% YoY decline - pre-revenue stage with no commercialized products
  • ! Negative operating cash flow of -4.4M indicating rapid cash burn and uncertain path to profitability
  • ! Limited cash runway of approximately 3-4 quarters at current burn rate before liquidity depletion
  • ! No insider buying activity in last 90 days suggesting lack of management confidence
  • ! Negative ROE (-8.5%) and ROA (-6.5%) reflect value destruction

Key Metrics to Watch

Claude
  • * Quarterly cash burn rate and remaining cash runway
  • * Clinical pipeline advancement and regulatory milestones for product candidates
  • * Time to first commercial revenue event and market acceptance

Synlogic, Inc.. (SYBX) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-1.0M
EPS (Diluted)
$-0.08
Free Cash Flow
$-4.4M
Total Assets
$15.4M
Cash Position
$14.7M

💡 AI Analyst Insight

Strong liquidity with a 4.30x current ratio provides a solid financial cushion.

SYBX Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -8.5%
ROA -6.5%
FCF Margin N/A

SYBX vs Healthcare Sector: How Synlogic, Inc.. Compares

How Synlogic, Inc.. compares to Healthcare sector averages

Net Margin
SYBX 0.0%
vs
Sector Avg 12.0%
SYBX Sector
ROE
SYBX -8.5%
vs
Sector Avg 15.0%
SYBX Sector
Current Ratio
SYBX 4.3x
vs
Sector Avg 2.0x
SYBX Sector
Debt/Equity
SYBX 0.0x
vs
Sector Avg 0.6x
SYBX Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Synlogic, Inc.. Stock Overvalued? SYBX Valuation Analysis 2026

Based on fundamental analysis, Synlogic, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-8.5%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Synlogic, Inc.. Balance Sheet: SYBX Debt, Cash & Liquidity

Current Ratio
4.30x
Quick Ratio
4.30x
Debt/Equity
0.00x
Debt/Assets
9.2%
Interest Coverage
N/A
Long-term Debt
N/A

SYBX Revenue & Earnings Growth: 5-Year Financial Trend

SYBX 5-year financial data: Year 2021: Revenue $1.8M, Net Income -$59.2M, EPS N/A. Year 2022: Revenue $1.8M, Net Income -$60.6M, EPS $-1.09. Year 2023: Revenue $3.4M, Net Income -$66.1M, EPS $-13.83. Year 2024: Revenue $3.4M, Net Income -$61.3M, EPS $-9.42. Year 2025: Revenue $8.0K, Net Income -$23.4M, EPS $-1.92.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Synlogic, Inc..'s revenue has declined by 100% over the 5-year period, indicating business contraction. The most recent EPS of $-1.92 indicates the company is currently unprofitable.

SYBX Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

SYBX Quarterly Earnings & Performance

Quarterly financial performance data for Synlogic, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 N/A -$117.0K $-0.01
Q2 2025 N/A -$212.0K $-0.02
Q1 2025 N/A $317.0K $0.03
Q3 2024 N/A -$117.0K $-0.01
Q2 2024 N/A $2.0M $0.16
Q1 2024 $8.0K -$15.6M $-2.60
Q3 2023 $393.0K -$12.1M $-2.57
Q2 2023 $35.0K -$15.0M $-0.21

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Synlogic, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$4.4M
Cash generated from operations
Dividends
None
No dividend program

SYBX SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Synlogic, Inc.. (CIK: 0001527599)

📋 Recent SEC Filings

Date Form Document Action
Mar 12, 2026 10-K sybx-20251231.htm View →
Jan 20, 2026 8-K sybx-20260116.htm View →
Dec 16, 2025 8-K sybx-20251215.htm View →
Nov 26, 2025 8-K sybx-20251121.htm View →
Nov 13, 2025 10-Q sybx-20250930.htm View →

Frequently Asked Questions about SYBX

What is the AI rating for SYBX?

Synlogic, Inc.. (SYBX) has an AI rating of STRONG SELL with 35% confidence, based on fundamental analysis of SEC EDGAR filings.

What are SYBX's key strengths?

Claude: Strong liquidity position with 4.30x current ratio and 14.7M cash on hand. Zero debt burden with 0.00x Debt/Equity ratio.

What are the risks of investing in SYBX?

Claude: Zero revenue with 100% YoY decline - pre-revenue stage with no commercialized products. Negative operating cash flow of -4.4M indicating rapid cash burn and uncertain path to profitability.

What is SYBX's revenue and growth?

Synlogic, Inc.. reported revenue of $0.0.

Does SYBX pay dividends?

Synlogic, Inc.. does not currently pay dividends.

Where can I find SYBX SEC filings?

Official SEC filings for Synlogic, Inc.. (CIK: 0001527599) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is SYBX's EPS?

Synlogic, Inc.. has a diluted EPS of $-0.08.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is SYBX a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Synlogic, Inc.. has a STRONG SELL rating with 35% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is SYBX stock overvalued or undervalued?

Valuation metrics for SYBX: ROE of -8.5% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy SYBX stock in 2026?

Our dual AI analysis gives Synlogic, Inc.. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is SYBX's free cash flow?

Synlogic, Inc..'s operating cash flow is $-4.4M, with capital expenditures of $0.0.

How does SYBX compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -8.5% (avg: 15%), current ratio 4.30 (avg: 2).

Top Rated Stocks
NSSC 92% MLI 92% MELI 92% MDXG 92% MANH 92% INVA 92% GGG 92% GCT 92% FTNT 92% FSLR 92%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 17, 2026 | Data as of: 2025-12-31 | Powered by Claude AI