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Schrodinger, Inc. (SDGR) Fundamental Analysis & AI Grade 2026

SDGR Nasdaq Pharmaceutical Preparations DE CIK: 0001490978
Updated This Month • Analysis: May 7, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
78% Confidence
N/A
C
78% Conf
Pending
Analysis scheduled

📊 SDGR Key Takeaways

Revenue: $58.6M
Net Margin: -102.5%
Free Cash Flow: $-17.3M
Current Ratio: 2.74x
Debt/Equity: 0.00x
EPS: $-0.81
AI Grade: C with 78% confidence
Schrodinger, Inc. (SDGR) receives a C fundamental grade with 78% confidence from our AI analysis based on SEC 10-K filings. With revenue of $58.6M, net profit margin of -102.5%, and return on equity (ROE) of -19.1%, Schrodinger, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete SDGR stock analysis for 2026.

Is Schrodinger, Inc. (SDGR) a Good Investment?

Claude

Schrodinger is a cash-burning biotech company with zero revenue growth, deteriorating operational losses reaching -83.3% margin, and negative free cash flow of -$17.3M annually. While the company maintains a fortress balance sheet with $260M cash and no debt, the flat-lined business lacks commercialization traction and shows no clear path to operational profitability.

Schrodinger, Inc. Key Strengths (SDGR)

Claude
  • + Fortress balance sheet with $260.3M cash reserves and zero debt, providing 15-year cash runway
  • + Healthy gross margins of 50.4% demonstrate viable product economics at the unit level
  • + Excellent liquidity metrics (2.74x current ratio) ensuring near-term financial flexibility

SDGR Stock Risks: Schrodinger, Inc. Investment Risks

Claude
  • ! Negative free cash flow of -$17.3M annually with no improvement trajectory despite substantial cash reserves
  • ! Revenue completely stalled at $58.6M with 0% YoY growth indicating failed commercialization momentum
  • ! Unsustainable cost structure with operating losses of -$48.8M (-83.3% margin) that exceed gross profit generation

Key Metrics to Watch

Claude
  • * Revenue growth acceleration from 0% to establish market traction and product demand
  • * Operating cash flow inflection from negative to positive demonstrating path to breakeven
  • * Operating margin improvement toward breakeven as revenue scales or cost structure optimizes

Schrodinger, Inc. (SDGR) Financial Metrics & Key Ratios

Revenue
$58.6M
Net Income
$-60.0M
EPS (Diluted)
$-0.81
Free Cash Flow
$-17.3M
Total Assets
$634.2M
Cash Position
$260.3M

💡 AI Analyst Insight

Strong liquidity with a 2.74x current ratio provides a solid financial cushion.

SDGR Profit Margin, ROE & Profitability Analysis

Gross Margin 50.4%
Operating Margin -83.3%
Net Margin -102.5%
ROE -19.1%
ROA -9.5%
FCF Margin -29.6%

SDGR vs Healthcare Sector: How Schrodinger, Inc. Compares

How Schrodinger, Inc. compares to Healthcare sector averages

Net Margin
SDGR -102.5%
vs
Sector Avg 12.0%
SDGR Sector
ROE
SDGR -19.1%
vs
Sector Avg 15.0%
SDGR Sector
Current Ratio
SDGR 2.7x
vs
Sector Avg 2.0x
SDGR Sector
Debt/Equity
SDGR 0.0x
vs
Sector Avg 0.6x
SDGR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Schrodinger, Inc. Stock Overvalued? SDGR Valuation Analysis 2026

Based on fundamental analysis, Schrodinger, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-19.1%
Sector avg: 15%
Net Profit Margin
-102.5%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Schrodinger, Inc. Balance Sheet: SDGR Debt, Cash & Liquidity

Current Ratio
2.74x
Quick Ratio
2.74x
Debt/Equity
0.00x
Debt/Assets
50.6%
Interest Coverage
N/A
Long-term Debt
N/A

SDGR Revenue & Earnings Growth: 5-Year Financial Trend

SDGR 5-year financial data: Year 2020: Revenue $108.1M, Net Income N/A, EPS N/A. Year 2021: Revenue $137.9M, Net Income -$24.6M, EPS N/A. Year 2023: Revenue $216.7M, Net Income -$100.4M, EPS $-1.42. Year 2024: Revenue $216.7M, Net Income -$149.2M, EPS $-2.10. Year 2025: Revenue $255.9M, Net Income $40.7M, EPS $0.54.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Schrodinger, Inc.'s revenue has grown significantly by 137% over the 5-year period, indicating strong business expansion. The most recent EPS of $0.54 reflects profitable operations.

SDGR Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-29.6%
Free cash flow / Revenue

SDGR Quarterly Earnings & Performance

Quarterly financial performance data for Schrodinger, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $58.6M -$59.8M $-0.81
Q3 2025 $35.3M -$32.8M $-0.45
Q2 2025 $47.3M -$43.2M $-0.59
Q1 2025 $36.6M -$54.7M $-0.76
Q3 2024 $35.3M $4.3M $-0.52
Q2 2024 $35.2M $4.3M $0.06
Q1 2024 $36.6M -$54.7M $-0.76
Q3 2023 $37.0M $4.3M $-0.56

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Schrodinger, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$14.8M
Cash generated from operations
Capital Expenditures
$2.5M
Investment in assets
Dividends
None
No dividend program

SDGR SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Schrodinger, Inc. (CIK: 0001490978)

📋 Recent SEC Filings

Date Form Document Action
May 20, 2026 8-K sdgr-20260518.htm View →
May 5, 2026 10-Q sdgr-20260331.htm View →
May 5, 2026 8-K sdgr-20260505.htm View →
Apr 28, 2026 DEF 14A sdgr-20260427.htm View →
Apr 17, 2026 4 xslF345X06/wk-form4_1776463772.xml View →

Frequently Asked Questions about SDGR

What is the AI rating for SDGR?

Schrodinger, Inc. (SDGR) has an AI grade of C with 78% confidence, based on fundamental analysis of SEC EDGAR filings.

What are SDGR's key strengths?

Claude: Fortress balance sheet with $260.3M cash reserves and zero debt, providing 15-year cash runway. Healthy gross margins of 50.4% demonstrate viable product economics at the unit level.

What are the risks of investing in SDGR?

Claude: Negative free cash flow of -$17.3M annually with no improvement trajectory despite substantial cash reserves. Revenue completely stalled at $58.6M with 0% YoY growth indicating failed commercialization momentum.

What is SDGR's revenue and growth?

Schrodinger, Inc. reported revenue of $58.6M.

Does SDGR pay dividends?

Schrodinger, Inc. does not currently pay dividends.

Where can I find SDGR SEC filings?

Official SEC filings for Schrodinger, Inc. (CIK: 0001490978) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is SDGR's EPS?

Schrodinger, Inc. has a diluted EPS of $-0.81.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is SDGR's fundamental grade?

Based on our AI fundamental analysis in June 2026, Schrodinger, Inc. has a C grade with 78% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is SDGR stock overvalued or undervalued?

Valuation metrics for SDGR: ROE of -19.1% (sector avg: 15%), net margin of -102.5% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is SDGR's AI grade for 2026?

Our dual AI analysis gives Schrodinger, Inc. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is SDGR's free cash flow?

Schrodinger, Inc.'s operating cash flow is $-14.8M, with capital expenditures of $2.5M. FCF margin is -29.6%.

How does SDGR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -102.5% (avg: 12%), ROE -19.1% (avg: 15%), current ratio 2.74 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 7, 2026 | Data as of: 2026-03-31 | Powered by Claude AI