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Protalix BioTherapeutics, Inc. (PLX) Fundamental Analysis & AI Grade 2026

PLX NYSE Biological Products, (No Diagnostic Substances) DE CIK: 0001006281
Updated This Month • Analysis: May 14, 2026 • SEC Data: 2026-03-31
Combined AI Grade
B
52% Confidence
N/A
B
52% Conf
Pending
Analysis scheduled

📊 PLX Key Takeaways

Revenue: $33.8M
Net Margin: 54.3%
Free Cash Flow: $21.3M
Current Ratio: 3.15x
Debt/Equity: 0.01x
EPS: $0.22
AI Grade: B with 52% confidence
Protalix BioTherapeutics, Inc. (PLX) receives a B fundamental grade with 52% confidence from our AI analysis based on SEC 10-K filings. With revenue of $33.8M, net profit margin of 54.3%, and return on equity (ROE) of 27.2%, Protalix BioTherapeutics, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PLX stock analysis for 2026.

Is Protalix BioTherapeutics, Inc. (PLX) a Good Investment?

Claude

Protalix demonstrates exceptional financial health with strong cash reserves ($41M), minimal debt, and robust free cash flow generation ($21.3M), but operational fundamentals are concerning with declining revenue (-1.2% YoY), critically low gross margins (0.6%), and apparent recovery from a significant prior-year loss rather than sustainable profit growth.

Protalix BioTherapeutics, Inc. Key Strengths (PLX)

Claude
  • + Strong balance sheet with $41M cash and 0.01x debt-to-equity ratio
  • + Excellent liquidity metrics (3.15x current ratio) providing downside protection
  • + Positive free cash flow of $21.3M with 63% FCF margin demonstrating cash generation capability
  • + High ROE (27.2%) and ROA (17.9%) metrics reflecting efficient capital deployment
  • + Minimal long-term debt ($912K) limiting financial risk

PLX Stock Risks: Protalix BioTherapeutics, Inc. Investment Risks

Claude
  • ! Declining revenue trajectory (-1.2% YoY) in a competitive biotech sector
  • ! Unsustainably low gross margin of 0.6% indicating severe product/operational challenges
  • ! Massive net income decline of -325% YoY suggests comparison to prior-year loss with questionable profit sustainability
  • ! Disconnect between gross profit ($198K) and operating income ($21.1M) implies reliance on non-operating gains
  • ! Zero insider Form 4 filings in 90 days suggests lack of management conviction

Key Metrics to Watch

Claude
  • * Revenue growth acceleration or stabilization
  • * Gross margin expansion toward industry-standard levels (>40% for biotech)
  • * Sustainability of operating cash flow as revenue trends evolve
  • * R&D pipeline progress and new product commercialization
  • * Source and sustainability of non-operating gains driving profitability

Protalix BioTherapeutics, Inc. (PLX) Financial Metrics & Key Ratios

Revenue
$33.8M
Net Income
$18.3M
EPS (Diluted)
$0.22
Free Cash Flow
$21.3M
Total Assets
$102.3M
Cash Position
$41.0M

💡 AI Analyst Insight

The 63.0% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 3.15x current ratio provides a solid financial cushion.

PLX Profit Margin, ROE & Profitability Analysis

Gross Margin 0.6%
Operating Margin 62.7%
Net Margin 54.3%
ROE 27.2%
ROA 17.9%
FCF Margin 63.0%

PLX vs Healthcare Sector: How Protalix BioTherapeutics, Inc. Compares

How Protalix BioTherapeutics, Inc. compares to Healthcare sector averages

Net Margin
PLX 54.3%
vs
Sector Avg 12.0%
PLX Sector
ROE
PLX 27.2%
vs
Sector Avg 15.0%
PLX Sector
Current Ratio
PLX 3.2x
vs
Sector Avg 2.0x
PLX Sector
Debt/Equity
PLX 0.0x
vs
Sector Avg 0.6x
PLX Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Protalix BioTherapeutics, Inc. Stock Overvalued? PLX Valuation Analysis 2026

Based on fundamental analysis, Protalix BioTherapeutics, Inc. appears fundamentally strong relative to the Healthcare sector in 2026.

Return on Equity
27.2%
Sector avg: 15%
Net Profit Margin
54.3%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.01x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Protalix BioTherapeutics, Inc. Balance Sheet: PLX Debt, Cash & Liquidity

Current Ratio
3.15x
Quick Ratio
2.04x
Debt/Equity
0.01x
Debt/Assets
34.3%
Interest Coverage
5.96x
Long-term Debt
$912.0K

PLX Revenue & Earnings Growth: 5-Year Financial Trend

PLX 5-year financial data: Year 2021: Revenue $62.9M, Net Income -$18.3M, EPS $-1.23. Year 2022: Revenue $62.9M, Net Income -$6.5M, EPS $-0.22. Year 2023: Revenue $65.5M, Net Income -$27.6M, EPS $-0.62. Year 2024: Revenue $65.5M, Net Income -$14.9M, EPS $-0.31. Year 2025: Revenue $65.5M, Net Income $8.3M, EPS $0.09.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Protalix BioTherapeutics, Inc.'s revenue has shown modest growth of 4% over the 5-year period. The most recent EPS of $0.09 reflects profitable operations.

PLX Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
63.0%
Free cash flow / Revenue

PLX Quarterly Earnings & Performance

Quarterly financial performance data for Protalix BioTherapeutics, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $10.1M -$3.6M $-0.05
Q3 2025 $17.9M -$1.1M $-0.01
Q2 2025 $13.5M $164.0K $0.00
Q1 2025 $3.7M -$3.6M $-0.05
Q3 2024 $10.3M -$1.9M $0.03
Q2 2024 $13.5M -$2.2M $-0.03
Q1 2024 $3.7M -$3.1M $-0.05
Q3 2023 $10.3M -$1.9M $-0.04

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Protalix BioTherapeutics, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$22.0M
Cash generated from operations
Capital Expenditures
$761.0K
Investment in assets
Dividends
None
No dividend program

PLX SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Protalix BioTherapeutics, Inc. (CIK: 0001006281)

📋 Recent SEC Filings

Date Form Document Action
May 21, 2026 8-K plx-20260521x8k.htm View →
May 13, 2026 10-Q plx-20260331x10q.htm View →
May 13, 2026 8-K plx-20260513x8k.htm View →
Apr 30, 2026 DEF 14A plx-20260625xdef14a.htm View →
Mar 18, 2026 10-K plx-20251231x10k.htm View →

Frequently Asked Questions about PLX

What is the AI rating for PLX?

Protalix BioTherapeutics, Inc. (PLX) has an AI grade of B with 52% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PLX's key strengths?

Claude: Strong balance sheet with $41M cash and 0.01x debt-to-equity ratio. Excellent liquidity metrics (3.15x current ratio) providing downside protection.

What are the risks of investing in PLX?

Claude: Declining revenue trajectory (-1.2% YoY) in a competitive biotech sector. Unsustainably low gross margin of 0.6% indicating severe product/operational challenges.

What is PLX's revenue and growth?

Protalix BioTherapeutics, Inc. reported revenue of $33.8M.

Does PLX pay dividends?

Protalix BioTherapeutics, Inc. does not currently pay dividends.

Where can I find PLX SEC filings?

Official SEC filings for Protalix BioTherapeutics, Inc. (CIK: 0001006281) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PLX's EPS?

Protalix BioTherapeutics, Inc. has a diluted EPS of $0.22.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is PLX's fundamental grade?

Based on our AI fundamental analysis in May 2026, Protalix BioTherapeutics, Inc. has a B grade with 52% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is PLX stock overvalued or undervalued?

Valuation metrics for PLX: ROE of 27.2% (sector avg: 15%), net margin of 54.3% (sector avg: 12%). Higher ROE suggests strong returns relative to peers.

What is PLX's AI grade for 2026?

Our dual AI analysis gives Protalix BioTherapeutics, Inc. a combined B grade for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is PLX's free cash flow?

Protalix BioTherapeutics, Inc.'s operating cash flow is $22.0M, with capital expenditures of $761.0K. FCF margin is 63.0%.

How does PLX compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 54.3% (avg: 12%), ROE 27.2% (avg: 15%), current ratio 3.15 (avg: 2).

Why is PLX's return on equity (ROE) so high?

Protalix BioTherapeutics, Inc. has a return on equity of 27.2%, significantly above the Healthcare sector average of 15%. A high ROE indicates the company is efficient at generating profits from shareholder equity. This is supported by a 54.3% net margin.

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 14, 2026 | Data as of: 2026-03-31 | Powered by Claude AI