← Back to All US Stocks

Palisade Bio, Inc.. (PALI) Stock Fundamental Analysis & AI Rating 2026

PALI Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001357459
Recently Updated • Analysis: Apr 13, 2026 • SEC Data: 2025-12-31
SELL
68% Conf
Pending
Analysis scheduled

📊 PALI Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-10.8M
Current Ratio: 28.95x
Debt/Equity: 0.00x
EPS: $-0.30
AI Rating: SELL with 68% confidence
Palisade Bio, Inc.. (PALI) receives a SELL rating with 68% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -13.0%, Palisade Bio, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete PALI stock analysis for 2026.

Is Palisade Bio, Inc.. (PALI) a Good Investment?

Claude

Palisade Bio is a pre-revenue stage biotech company with exceptional liquidity ($133.4M cash) but zero commercial traction, active cash burn of $10.8M annually, and value destruction evident in negative ROE/ROA. While the balance sheet provides 12+ years of runway, the fundamental absence of revenue, ongoing losses, and lack of visible profitability pathway make this a high-risk speculation without clinical or commercial validation.

Why Buy Palisade Bio, Inc.. Stock? PALI Key Strengths

Claude
  • + Exceptional liquidity: $133.4M cash with 28.95x current ratio
  • + Minimal debt burden: Only $87K long-term debt with 0.0x debt-to-equity
  • + Strong equity cushion: $129.4M stockholders' equity provides substantial R&D funding runway (12+ years at current burn rate)

PALI Stock Risks: Palisade Bio, Inc.. Investment Risks

Claude
  • ! Zero revenue: No commercial product validation or market traction
  • ! Active cash burn: -$10.8M operating cash flow annually destroying shareholder value
  • ! Pre-commercialization risk: All profitability metrics N/A; no visible path to profitability or timeline disclosed
  • ! Typical biotech execution risks: Clinical trial failures, regulatory rejection, delayed timelines not quantified

Key Metrics to Watch

Claude
  • * Operating cash burn trajectory and cash runway depletion timeline
  • * Clinical trial progress milestones and regulatory pathway advancement
  • * Revenue recognition date and initial commercial adoption metrics
  • * Operating expense efficiency and R&D productivity

Palisade Bio, Inc.. (PALI) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-16.8M
EPS (Diluted)
$-0.30
Free Cash Flow
$-10.8M
Total Assets
$134.3M
Cash Position
$133.4M

💡 AI Analyst Insight

Strong liquidity with a 28.95x current ratio provides a solid financial cushion.

PALI Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -13.0%
ROA -12.5%
FCF Margin N/A

PALI vs Healthcare Sector: How Palisade Bio, Inc.. Compares

How Palisade Bio, Inc.. compares to Healthcare sector averages

Net Margin
PALI 0.0%
vs
Sector Avg 12.0%
PALI Sector
ROE
PALI -13.0%
vs
Sector Avg 15.0%
PALI Sector
Current Ratio
PALI 29.0x
vs
Sector Avg 2.0x
PALI Sector
Debt/Equity
PALI 0.0x
vs
Sector Avg 0.6x
PALI Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Palisade Bio, Inc.. Stock Overvalued? PALI Valuation Analysis 2026

Based on fundamental analysis, Palisade Bio, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-13.0%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Palisade Bio, Inc.. Balance Sheet: PALI Debt, Cash & Liquidity

Current Ratio
28.95x
Quick Ratio
28.95x
Debt/Equity
0.00x
Debt/Assets
3.7%
Interest Coverage
-2,257.00x
Long-term Debt
$87.0K

PALI Revenue & Earnings Growth: 5-Year Financial Trend

PALI 5-year financial data: Year 2023: Revenue $250.0K, Net Income -$14.3M, EPS $-16.53. Year 2024: Revenue $250.0K, Net Income -$12.3M, EPS $-27.01.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Palisade Bio, Inc..'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-10.19 indicates the company is currently unprofitable.

PALI Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

PALI Quarterly Earnings & Performance

Quarterly financial performance data for Palisade Bio, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2024 N/A -$3.5M $-2.32
Q2 2024 N/A -$3.4M $-3.32
Q1 2024 N/A -$2.3M $-4.59
Q3 2023 N/A -$3.6M $-0.49
Q2 2023 N/A -$2.3M $-0.53
Q1 2023 N/A -$2.3M $-0.54

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Palisade Bio, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$10.8M
Cash generated from operations
Dividends
None
No dividend program

PALI SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Palisade Bio, Inc.. (CIK: 0001357459)

📋 Recent SEC Filings

Date Form Document Action
Apr 2, 2026 8-K form8-k.htm View →
Mar 20, 2026 10-K pali-20251231.htm View →
Feb 13, 2026 4 xslF345X05/ownership.xml View →
Feb 13, 2026 4 xslF345X05/ownership.xml View →
Feb 11, 2026 4 xslF345X05/ownership.xml View →

Frequently Asked Questions about PALI

What is the AI rating for PALI?

Palisade Bio, Inc.. (PALI) has an AI rating of SELL with 68% confidence, based on fundamental analysis of SEC EDGAR filings.

What are PALI's key strengths?

Claude: Exceptional liquidity: $133.4M cash with 28.95x current ratio. Minimal debt burden: Only $87K long-term debt with 0.0x debt-to-equity.

What are the risks of investing in PALI?

Claude: Zero revenue: No commercial product validation or market traction. Active cash burn: -$10.8M operating cash flow annually destroying shareholder value.

What is PALI's revenue and growth?

Palisade Bio, Inc.. reported revenue of $0.0.

Does PALI pay dividends?

Palisade Bio, Inc.. does not currently pay dividends.

Where can I find PALI SEC filings?

Official SEC filings for Palisade Bio, Inc.. (CIK: 0001357459) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is PALI's EPS?

Palisade Bio, Inc.. has a diluted EPS of $-0.30.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is PALI a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Palisade Bio, Inc.. has a SELL rating with 68% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is PALI stock overvalued or undervalued?

Valuation metrics for PALI: ROE of -13.0% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy PALI stock in 2026?

Our dual AI analysis gives Palisade Bio, Inc.. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is PALI's free cash flow?

Palisade Bio, Inc..'s operating cash flow is $-10.8M, with capital expenditures of $0.0.

How does PALI compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -13.0% (avg: 15%), current ratio 28.95 (avg: 2).

Top Rated Stocks
NSSC 92% MLI 92% MELI 92% MDXG 92% MANH 92% INVA 92% GGG 92% GCT 92% FTNT 92% FSLR 92%
Sector: All Healthcare Stocks →
Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 13, 2026 | Data as of: 2025-12-31 | Powered by Claude AI