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Olema Pharmaceuticals, Inc. (OLMA) Fundamental Analysis & AI Grade 2026

OLMA Nasdaq Pharmaceutical Preparations DE CIK: 0001750284
Updated This Month • Analysis: May 14, 2026 • SEC Data: 2026-03-31
Combined AI Grade
C
66% Confidence
AGREEMENT
C
70% Conf
B
63% Conf

📊 OLMA Key Takeaways

Revenue: N/A
Net Margin: N/A
Free Cash Flow: $-46.0M
Current Ratio: 10.88x
Debt/Equity: 0.00x
EPS: $-0.52
AI Grade: C with 70% confidence
Olema Pharmaceuticals, Inc. (OLMA) receives a C fundamental grade with 66% confidence from our AI analysis based on SEC 10-K filings., and return on equity (ROE) of -11.0% Below is our complete OLMA stock analysis for 2026.

Is Olema Pharmaceuticals, Inc. (OLMA) a Good Investment?

Claude

Olema is a pre-commercial pharmaceutical company with no revenue and significant annual operating cash burn of $46M, consuming approximately 1.1 years of available cash reserves. While the balance sheet is strong with $480.5M equity, zero debt, and excellent liquidity, the company remains dependent on uncertain clinical development and regulatory approval with no visible near-term revenue catalysts. The improving loss trajectory (25.5% YoY improvement) is encouraging but insufficient to offset the fundamental challenges inherent in pre-revenue biotech.

ChatGPT

Pre‑revenue biotech with very strong liquidity (current/quick ~10x) and no debt, providing near‑term financial flexibility. Fundamentals remain weak with large operating losses (−$178.7M) and heavy cash burn (OCF −$146.7M) driving negative ROE/ROA, despite a 15% YoY EPS improvement. Without revenue, execution depends on disciplined expense management and securing non‑dilutive funding or partnerships to extend runway.

Olema Pharmaceuticals, Inc. Key Strengths (OLMA)

Claude
  • + Exceptional balance sheet strength with $480.5M stockholders equity and zero long-term debt
  • + Outstanding liquidity position with 10.88x current ratio and minimal near-term financing pressure
  • + Improving loss trajectory with net income declining 25.5% YoY and EPS improving 15.0% YoY, indicating cost management progress
ChatGPT
  • + Robust liquidity (current and quick ratio 9.95x)
  • + Zero leverage (Debt/Equity 0.00x)
  • + Large asset and equity base supporting operations

OLMA Stock Risks: Olema Pharmaceuticals, Inc. Investment Risks

Claude
  • ! No revenue generation - entirely pre-commercial with success dependent on pipeline clinical development outcomes
  • ! Limited cash runway of approximately 1.1 years at current $46M annual operating cash burn, requiring future funding or clinical success
  • ! High regulatory and clinical development risk typical of early-stage biotech with no approved commercial products or revenue diversification
ChatGPT
  • ! Sustained negative operating cash flow with no revenue
  • ! Dilution risk to fund ongoing R&D and operations
  • ! Uncertain path to profitability (negative ROE/ROA)

Key Metrics to Watch

Claude
  • * Quarterly cash burn rate and path to achieving positive operating cash flow or revenue milestone
  • * Clinical trial advancement, FDA interactions, regulatory milestones, and competitive pipeline developments
ChatGPT
  • * Operating cash flow (burn) trend
  • * Total liquid assets (cash + short-term investments) runway

Olema Pharmaceuticals, Inc. (OLMA) Financial Metrics & Key Ratios

Revenue
N/A
Net Income
$-53.1M
EPS (Diluted)
$-0.52
Free Cash Flow
$-46.0M
Total Assets
$530.6M
Cash Position
$52.5M

💡 AI Analyst Insight

Strong liquidity with a 10.88x current ratio provides a solid financial cushion.

OLMA Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -11.0%
ROA -10.0%
FCF Margin N/A

OLMA vs Healthcare Sector: How Olema Pharmaceuticals, Inc. Compares

How Olema Pharmaceuticals, Inc. compares to Healthcare sector averages

Net Margin
OLMA 0.0%
vs
Sector Avg 12.0%
OLMA Sector
ROE
OLMA -11.0%
vs
Sector Avg 15.0%
OLMA Sector
Current Ratio
OLMA 10.9x
vs
Sector Avg 2.0x
OLMA Sector
Debt/Equity
OLMA 0.0x
vs
Sector Avg 0.6x
OLMA Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Olema Pharmaceuticals, Inc. Stock Overvalued? OLMA Valuation Analysis 2026

Based on fundamental analysis, Olema Pharmaceuticals, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-11.0%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Olema Pharmaceuticals, Inc. Balance Sheet: OLMA Debt, Cash & Liquidity

Current Ratio
10.88x
Quick Ratio
10.88x
Debt/Equity
0.00x
Debt/Assets
9.5%
Interest Coverage
-88.80x
Long-term Debt
N/A

OLMA Revenue & Earnings Growth: 5-Year Financial Trend

OLMA 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Olema Pharmaceuticals, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-2.20 indicates the company is currently unprofitable.

OLMA Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

Olema Pharmaceuticals, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$46.0M
Cash generated from operations
Dividends
None
No dividend program

OLMA SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Olema Pharmaceuticals, Inc. (CIK: 0001750284)

📋 Recent SEC Filings

Date Form Document Action
May 26, 2026 8-K olma-20260526.htm View →
May 21, 2026 8-K olma-20260521.htm View →
May 12, 2026 10-Q olma-20260331.htm View →
May 12, 2026 8-K olma-20260512.htm View →
May 1, 2026 8-K olma-20260427.htm View →

Frequently Asked Questions about OLMA

What is the AI rating for OLMA?

Olema Pharmaceuticals, Inc. (OLMA) has a Combined AI Grade of C from Claude (C) and ChatGPT (B) with 66% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are OLMA's key strengths?

Claude: Exceptional balance sheet strength with $480.5M stockholders equity and zero long-term debt. Outstanding liquidity position with 10.88x current ratio and minimal near-term financing pressure. ChatGPT: Robust liquidity (current and quick ratio 9.95x). Zero leverage (Debt/Equity 0.00x).

What are the risks of investing in OLMA?

Claude: No revenue generation - entirely pre-commercial with success dependent on pipeline clinical development outcomes. Limited cash runway of approximately 1.1 years at current $46M annual operating cash burn, requiring future funding or clinical success. ChatGPT: Sustained negative operating cash flow with no revenue. Dilution risk to fund ongoing R&D and operations.

What is OLMA's revenue and growth?

Olema Pharmaceuticals, Inc. reported revenue of N/A.

Does OLMA pay dividends?

Olema Pharmaceuticals, Inc. does not currently pay dividends.

Where can I find OLMA SEC filings?

Official SEC filings for Olema Pharmaceuticals, Inc. (CIK: 0001750284) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is OLMA's EPS?

Olema Pharmaceuticals, Inc. has a diluted EPS of $-0.52.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined grade reflects both perspectives for balanced insights.

What is OLMA's fundamental grade?

Based on our AI fundamental analysis in May 2026, Olema Pharmaceuticals, Inc. has a C grade with 66% confidence. Review the strengths and risks sections above for full context. This is not investment advice.

Is OLMA stock overvalued or undervalued?

Valuation metrics for OLMA: ROE of -11.0% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

What is OLMA's AI grade for 2026?

Our dual AI analysis gives Olema Pharmaceuticals, Inc. a combined C grade for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is OLMA's free cash flow?

Olema Pharmaceuticals, Inc.'s operating cash flow is $-46.0M, with capital expenditures of $0.0.

How does OLMA compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -11.0% (avg: 15%), current ratio 10.88 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 14, 2026 | Data as of: 2026-03-31 | Powered by Claude AI