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MNPR Stock Analysis 2026 - Monopar Therapeutics AI Rating

MNPR Nasdaq Pharmaceutical Preparations DE CIK: 0001645469
Recently Updated • Analysis: Apr 2, 2026 • SEC Data: 2025-12-31
SELL
85% Conf
Pending
Analysis scheduled

📊 MNPR Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-12.2M
Current Ratio: 51.35x
Debt/Equity: 0.00x
EPS: $0.00
AI Rating: SELL with 85% confidence

Is MNPR a Good Investment? Thesis Analysis

Claude

Monopar Therapeutics is a pre-revenue pharmaceutical company with significant ongoing losses and negative cash flow, indicating it is in early clinical development stages. While the company maintains a strong cash position of $61.8M and minimal debt, the current burn rate of $12.2M annually combined with zero revenue creates substantial viability risks without successful commercialization or additional financing.

Why Buy MNPR? Key Strengths

Claude
  • + Strong balance sheet with $61.8M in cash and negligible debt (Debt/Equity: 0.00x)
  • + Excellent liquidity position with 51.35x current ratio, providing runway for development activities
  • + Minimal liabilities ($2.9M) relative to assets ($140.7M) demonstrates conservative financial management
  • + Recent insider activity (5 Form 4 filings in 90 days) suggests ongoing management engagement

MNPR Investment Risks to Consider

Claude
  • ! Zero revenue generation indicates company is pre-commercialization with no approved products generating sales
  • ! Persistent operating losses (-$16.7M) and negative free cash flow (-$12.2M) require continued capital consumption
  • ! Cash runway concerns: at current burn rate of $12.2M annually, existing cash reserves provide only ~5 years of operations without additional revenue or financing
  • ! Pharmaceutical development risk: company faces typical biotech risks of clinical trial failures, regulatory rejection, and time-to-market delays
  • ! Negative ROE (-10.0%) and ROA (-9.7%) demonstrate shareholder value destruction in current operations

Key Metrics to Watch

Claude
  • * Quarterly operating cash burn rate and cash runway remaining
  • * Clinical trial progress and regulatory milestones for pipeline candidates
  • * Quarterly revenue achievement and commercialization timeline updates
  • * Changes in cash position and potential dilutive financing activities
  • * Operating loss trends and pathway to profitability demonstration

MNPR Financial Metrics

Revenue
$0.0
Net Income
$-13.7M
EPS (Diluted)
$0.00
Free Cash Flow
$-12.2M
Total Assets
$140.7M
Cash Position
$61.8M

💡 AI Analyst Insight

Strong liquidity with a 51.35x current ratio provides a solid financial cushion.

MNPR Profitability Ratios

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -10.0%
ROA -9.7%
FCF Margin N/A

MNPR vs Healthcare Sector

How Monopar Therapeutics compares to Healthcare sector averages

Net Margin
MNPR 0.0%
vs
Sector Avg 12.0%
MNPR Sector
ROE
MNPR -10.0%
vs
Sector Avg 15.0%
MNPR Sector
Current Ratio
MNPR 51.4x
vs
Sector Avg 2.0x
MNPR Sector
Debt/Equity
MNPR 0.0x
vs
Sector Avg 0.6x
MNPR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is MNPR Overvalued or Undervalued?

Based on fundamental analysis, Monopar Therapeutics has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-10.0%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

MNPR Balance Sheet & Liquidity

Current Ratio
51.35x
Quick Ratio
51.35x
Debt/Equity
0.00x
Debt/Assets
2.1%
Interest Coverage
N/A
Long-term Debt
N/A

MNPR 5-Year Financial Trend & Growth Analysis

MNPR 5-year financial data: Year 2018: Revenue $0, Net Income N/A, EPS N/A. Year 2019: Revenue $0, Net Income N/A, EPS N/A. Year 2023: Revenue $0, Net Income -$10.5M, EPS $-0.83. Year 2024: Revenue $0, Net Income -$8.4M, EPS $-3.04. Year 2025: Revenue $0, Net Income -$15.6M, EPS $-4.11.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Monopar Therapeutics's revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-4.11 indicates the company is currently unprofitable.

MNPR Growth Metrics (YoY)

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

MNPR Quarterly Performance

Quarterly financial performance data for Monopar Therapeutics including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 N/A -$1.3M $-0.37
Q2 2025 N/A -$1.6M $-0.35
Q1 2025 N/A -$1.6M $-0.38
Q3 2019 N/A -$640.2K N/A
Q2 2019 N/A -$640.2K N/A
Q1 2019 N/A -$640.2K N/A
Q3 2018 N/A -$640.2K N/A
Q2 2018 N/A -$591.4K N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

MNPR Capital Allocation

Operating Cash Flow
-$12.2M
Cash generated from operations
Stock Buybacks
$35.0M
Shares repurchased (TTM)
Dividends
None
No dividend program

MNPR SEC 10-K & 10-Q Filing Analysis

Access official SEC EDGAR filings for Monopar Therapeutics (CIK: 0001645469)

📋 Recent SEC Filings

Date Form Document Action
Apr 1, 2026 10-K/A mnpr20251231c_10ka.htm View →
Mar 27, 2026 8-K mnpr20260326_8k.htm View →
Mar 27, 2026 10-K mnpr20251231_10k.htm View →
Mar 4, 2026 4 xslF345X05/rdgdoc.xml View →
Mar 2, 2026 8-K mnpr20260302_8k.htm View →

Frequently Asked Questions about MNPR

What is the AI rating for MNPR?

Monopar Therapeutics (MNPR) has an AI rating of SELL with 85% confidence, based on fundamental analysis of SEC EDGAR filings.

What are MNPR's key strengths?

Claude: Strong balance sheet with $61.8M in cash and negligible debt (Debt/Equity: 0.00x). Excellent liquidity position with 51.35x current ratio, providing runway for development activities.

What are the risks of investing in MNPR?

Claude: Zero revenue generation indicates company is pre-commercialization with no approved products generating sales. Persistent operating losses (-$16.7M) and negative free cash flow (-$12.2M) require continued capital consumption.

What is MNPR's revenue and growth?

Monopar Therapeutics reported revenue of $0.0.

Does MNPR pay dividends?

Monopar Therapeutics does not currently pay dividends.

Where can I find MNPR SEC filings?

Official SEC filings for Monopar Therapeutics (CIK: 0001645469) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is MNPR's EPS?

Monopar Therapeutics has a diluted EPS of $0.00.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is MNPR a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Monopar Therapeutics has a SELL rating with 85% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is MNPR stock overvalued or undervalued?

Valuation metrics for MNPR: ROE of -10.0% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy MNPR stock in 2026?

Our dual AI analysis gives Monopar Therapeutics a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is MNPR's free cash flow?

Monopar Therapeutics's operating cash flow is $-12.2M, with capital expenditures of N/A.

How does MNPR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -10.0% (avg: 15%), current ratio 51.35 (avg: 2).

Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 2, 2026 | Data as of: 2025-12-31 | Powered by Claude AI