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Monopar Therapeutics (MNPR) Stock Fundamental Analysis & AI Rating 2026

MNPR Nasdaq Pharmaceutical Preparations DE CIK: 0001645469
Recently Updated • Analysis: May 15, 2026 • SEC Data: 2026-03-31
Combined AI Rating
SELL
66% Confidence
AGREEMENT
SELL
68% Conf
HOLD
64% Conf

📊 MNPR Key Takeaways

Revenue: $0.0
Net Margin: N/A
Free Cash Flow: $-3.5M
Current Ratio: 56.04x
Debt/Equity: 0.00x
EPS: $0.00
AI Rating: SELL with 68% confidence
Monopar Therapeutics (MNPR) receives a SELL rating with 66% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $0, and return on equity (ROE) of -2.9%, Monopar Therapeutics demonstrates mixed fundamentals in the Healthcare sector. Below is our complete MNPR stock analysis for 2026.

Is Monopar Therapeutics (MNPR) a Good Investment?

Claude

Pre-revenue pharmaceutical company with zero income generation and persistent operating losses (-$5.2M) demonstrates fundamental inability to generate cash from operations. While the $52.5M cash balance and zero debt provide substantial runway (~15 years at current burn), the lack of any revenue stream combined with -$3.5M annual cash consumption indicates execution risk without demonstrated commercial viability.

ChatGPT

Monopar is a pre-revenue biotech with substantial liquidity ($61.8M cash), zero debt, and minimal liabilities, supporting a multi-year operating runway. Losses remain material but improved YoY, indicating some cost discipline; however, without revenue, the path to profitability depends on clinical progress not reflected in these financials. On fundamentals alone, strong balance sheet strength offsets ongoing burn, meriting a neutral stance.

Why Buy Monopar Therapeutics Stock? MNPR Key Strengths

Claude
  • + Strong cash position ($52.5M) with minimal liabilities provides extended R&D funding runway
  • + Pristine balance sheet with $135.4M equity and zero debt minimizes financial distress risk
  • + Exceptional liquidity with 56.04x current ratio eliminates near-term solvency concerns
ChatGPT
  • + Exceptional liquidity (current/quick ~51x) and $61.8M cash
  • + Debt-free with minimal liabilities vs $140.7M assets
  • + Net loss improved ~12% YoY, suggesting expense control

MNPR Stock Risks: Monopar Therapeutics Investment Risks

Claude
  • ! Zero revenue generation with no demonstrated commercial product viability
  • ! Negative free cash flow (-$3.5M) and operating income (-$5.2M) indicate continued asset depletion
  • ! Classic biotech/pharma risk: early-stage development dependent on successful clinical trials and regulatory approval without proven execution history
ChatGPT
  • ! No revenue with sustained operating losses and negative ROE/ROA
  • ! Cash burn (-$12.2M OCF) could accelerate, raising dilution risk
  • ! Outcome and timing risk tied to clinical/regulatory milestones

Key Metrics to Watch

Claude
  • * Cash burn trajectory and remaining runway duration before liquidity becomes constrained
  • * Pipeline advancement: clinical trial progression, regulatory milestone achievements, or partnership announcements
  • * Time to first revenue-generating product approval or licensing event
ChatGPT
  • * Operating cash burn (TTM and quarterly trend)
  • * Cash and equivalents vs projected runway (12–24 months)

Monopar Therapeutics (MNPR) Financial Metrics & Key Ratios

Revenue
$0.0
Net Income
$-3.9M
EPS (Diluted)
$0.00
Free Cash Flow
$-3.5M
Total Assets
$138.0M
Cash Position
$52.5M

💡 AI Analyst Insight

Strong liquidity with a 56.04x current ratio provides a solid financial cushion.

MNPR Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -2.9%
ROA -2.8%
FCF Margin N/A

MNPR vs Healthcare Sector: How Monopar Therapeutics Compares

How Monopar Therapeutics compares to Healthcare sector averages

Net Margin
MNPR 0.0%
vs
Sector Avg 12.0%
MNPR Sector
ROE
MNPR -2.9%
vs
Sector Avg 15.0%
MNPR Sector
Current Ratio
MNPR 56.0x
vs
Sector Avg 2.0x
MNPR Sector
Debt/Equity
MNPR 0.0x
vs
Sector Avg 0.6x
MNPR Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Monopar Therapeutics Stock Overvalued? MNPR Valuation Analysis 2026

Based on fundamental analysis, Monopar Therapeutics has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-2.9%
Sector avg: 15%
Net Profit Margin
N/A
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Monopar Therapeutics Balance Sheet: MNPR Debt, Cash & Liquidity

Current Ratio
56.04x
Quick Ratio
56.04x
Debt/Equity
0.00x
Debt/Assets
1.9%
Interest Coverage
N/A
Long-term Debt
N/A

MNPR Revenue & Earnings Growth: 5-Year Financial Trend

MNPR 5-year financial data: Year 2018: Revenue $0, Net Income N/A, EPS N/A. Year 2019: Revenue $0, Net Income N/A, EPS N/A. Year 2023: Revenue $0, Net Income -$10.5M, EPS $-0.83. Year 2024: Revenue $0, Net Income -$8.4M, EPS $-3.04. Year 2025: Revenue $0, Net Income -$15.6M, EPS $-4.11.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Monopar Therapeutics's revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-4.11 indicates the company is currently unprofitable.

MNPR Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

MNPR Quarterly Earnings & Performance

Quarterly financial performance data for Monopar Therapeutics including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 N/A -$2.6M $-0.38
Q3 2025 N/A -$1.3M $-0.37
Q2 2025 N/A -$1.6M $-0.35
Q1 2025 N/A -$1.6M $-0.38
Q3 2019 N/A -$640.2K N/A
Q2 2019 N/A -$640.2K N/A
Q1 2019 N/A -$640.2K N/A
Q3 2018 N/A -$640.2K N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Monopar Therapeutics Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$3.5M
Cash generated from operations
Stock Buybacks
$35.0M
Shares repurchased (TTM)
Dividends
None
No dividend program

MNPR SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Monopar Therapeutics (CIK: 0001645469)

📋 Recent SEC Filings

Date Form Document Action
May 14, 2026 10-Q mnpr20260331_10q.htm View →
May 14, 2026 8-K mnpr20260513c_8k.htm View →
Apr 30, 2026 DEF 14A mnpr20260330_def14a.htm View →
Apr 20, 2026 8-K mnpr20260419_8k.htm View →
Apr 2, 2026 4 xslF345X06/rdgdoc.xml View →

Frequently Asked Questions about MNPR

What is the AI rating for MNPR?

Monopar Therapeutics (MNPR) has a Combined AI Rating of SELL from Claude (SELL) and ChatGPT (HOLD) with 66% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are MNPR's key strengths?

Claude: Strong cash position ($52.5M) with minimal liabilities provides extended R&D funding runway. Pristine balance sheet with $135.4M equity and zero debt minimizes financial distress risk. ChatGPT: Exceptional liquidity (current/quick ~51x) and $61.8M cash. Debt-free with minimal liabilities vs $140.7M assets.

What are the risks of investing in MNPR?

Claude: Zero revenue generation with no demonstrated commercial product viability. Negative free cash flow (-$3.5M) and operating income (-$5.2M) indicate continued asset depletion. ChatGPT: No revenue with sustained operating losses and negative ROE/ROA. Cash burn (-$12.2M OCF) could accelerate, raising dilution risk.

What is MNPR's revenue and growth?

Monopar Therapeutics reported revenue of $0.0.

Does MNPR pay dividends?

Monopar Therapeutics does not currently pay dividends.

Where can I find MNPR SEC filings?

Official SEC filings for Monopar Therapeutics (CIK: 0001645469) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is MNPR's EPS?

Monopar Therapeutics has a diluted EPS of $0.00.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is MNPR a good stock to buy right now?

Based on our AI fundamental analysis in May 2026, Monopar Therapeutics has a SELL rating with 66% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is MNPR stock overvalued or undervalued?

Valuation metrics for MNPR: ROE of -2.9% (sector avg: 15%), net margin of N/A (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy MNPR stock in 2026?

Our dual AI analysis gives Monopar Therapeutics a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is MNPR's free cash flow?

Monopar Therapeutics's operating cash flow is $-3.5M, with capital expenditures of N/A.

How does MNPR compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin N/A (avg: 12%), ROE -2.9% (avg: 15%), current ratio 56.04 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 15, 2026 | Data as of: 2026-03-31 | Powered by Claude AI