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MDGL Stock Analysis 2026 - MADRIGAL PHARMACEUTICALS, INC. AI Rating

MDGL Nasdaq Pharmaceutical Preparations DE CIK: 0001157601
Recently Updated • Analysis: Apr 1, 2026 • SEC Data: 2025-12-31
SELL
85% Conf
Pending
Analysis scheduled

📊 MDGL Key Takeaways

Revenue: $958.4M
Net Margin: -30.1%
Free Cash Flow: $-190.0M
Current Ratio: 4.01x
Debt/Equity: 0.56x
EPS: $-12.85
AI Rating: SELL with 85% confidence

Is MDGL a Good Investment? Thesis Analysis

Claude

Despite exceptional 432% revenue growth, Madrigal Pharmaceuticals remains deeply unprofitable with -$288.3M net loss and negative operating margins of -31.3%, indicating the company is burning cash faster than revenue growth can support. The -$190M negative free cash flow coupled with $339.9M long-term debt raises serious sustainability concerns, suggesting the current business model is not yet generating value despite significant top-line expansion.

Why Buy MDGL? Key Strengths

Claude
  • + Exceptional revenue growth of 432% YoY demonstrates strong market demand and successful commercialization
  • + Strong liquidity position with $198.7M cash and 4.01x current ratio provides runway for operations
  • + Relatively moderate debt-to-equity ratio of 0.56x shows reasonable leverage levels

MDGL Investment Risks to Consider

Claude
  • ! Severe profitability crisis: -$288.3M net loss and -$30.1% net margin indicate the company is unprofitable at scale
  • ! Negative free cash flow of -$190M annually is unsustainable without capital raises or achieving profitability
  • ! High cash burn rate relative to revenue suggests operational inefficiency and potential dilution risk for shareholders
  • ! Negative interest coverage of -91.0x indicates inability to service debt from operations

Key Metrics to Watch

Claude
  • * Path to operating profitability and timeline to positive operating margins
  • * Operating cash flow trajectory and monthly cash burn rate sustainability
  • * Gross margin improvement as manufacturing scales and fixed costs are absorbed across higher revenue base

MDGL Financial Metrics

Revenue
$958.4M
Net Income
$-288.3M
EPS (Diluted)
$-12.85
Free Cash Flow
$-190.0M
Total Assets
$1.3B
Cash Position
$198.7M

💡 AI Analyst Insight

Strong liquidity with a 4.01x current ratio provides a solid financial cushion.

MDGL Profitability Ratios

Gross Margin N/A
Operating Margin -31.3%
Net Margin -30.1%
ROE -47.8%
ROA -22.9%
FCF Margin -19.8%

MDGL vs Healthcare Sector

How MADRIGAL PHARMACEUTICALS, INC. compares to Healthcare sector averages

Net Margin
MDGL -30.1%
vs
Sector Avg 12.0%
MDGL Sector
ROE
MDGL -47.8%
vs
Sector Avg 15.0%
MDGL Sector
Current Ratio
MDGL 4.0x
vs
Sector Avg 2.0x
MDGL Sector
Debt/Equity
MDGL 0.6x
vs
Sector Avg 0.6x
MDGL Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is MDGL Overvalued or Undervalued?

Based on fundamental analysis, MADRIGAL PHARMACEUTICALS, INC. shows some fundamental concerns relative to the Healthcare sector in 2026.

Return on Equity
-47.8%
Sector avg: 15%
Net Profit Margin
-30.1%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.56x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

MDGL Balance Sheet & Liquidity

Current Ratio
4.01x
Quick Ratio
3.77x
Debt/Equity
0.56x
Debt/Assets
52.2%
Interest Coverage
-91.02x
Long-term Debt
$339.9M

MDGL 5-Year Financial Trend & Growth Analysis

MDGL 5-year financial data: Year 2024: Revenue $180.1M, Net Income -$295.4M, EPS $-17.23. Year 2025: Revenue $958.4M, Net Income -$373.6M, EPS $-19.99.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: MADRIGAL PHARMACEUTICALS, INC.'s revenue has grown significantly by 432% over the 5-year period, indicating strong business expansion. The most recent EPS of $-19.99 indicates the company is currently unprofitable.

MDGL Growth Metrics (YoY)

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-19.8%
Free cash flow / Revenue

MDGL Quarterly Performance

Quarterly financial performance data for MADRIGAL PHARMACEUTICALS, INC. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $62.2M -$42.3M $-4.92
Q2 2025 $14.6M -$42.3M $-1.90
Q1 2025 N/A -$73.2M $-3.32
Q3 2024 N/A -$76.9M $-4.92
Q2 2024 N/A -$76.9M $-4.69

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

MDGL Capital Allocation

Operating Cash Flow
-$189.6M
Cash generated from operations
Stock Buybacks
$32.0K
Shares repurchased (TTM)
Capital Expenditures
$467.0K
Investment in assets
Dividends
None
No dividend program

MDGL SEC 10-K & 10-Q Filing Analysis

Access official SEC EDGAR filings for MADRIGAL PHARMACEUTICALS, INC. (CIK: 0001157601)

📋 Recent SEC Filings

Date Form Document Action
Mar 6, 2026 4 xslF345X05/wk-form4_1772842708.xml View →
Mar 6, 2026 4 xslF345X05/wk-form4_1772840956.xml View →
Mar 6, 2026 4 xslF345X05/wk-form4_1772840042.xml View →
Mar 6, 2026 4 xslF345X05/wk-form4_1772838950.xml View →
Mar 6, 2026 4 xslF345X05/wk-form4_1772838445.xml View →

Frequently Asked Questions about MDGL

What is the AI rating for MDGL?

MADRIGAL PHARMACEUTICALS, INC. (MDGL) has an AI rating of SELL with 85% confidence, based on fundamental analysis of SEC EDGAR filings.

What are MDGL's key strengths?

Claude: Exceptional revenue growth of 432% YoY demonstrates strong market demand and successful commercialization. Strong liquidity position with $198.7M cash and 4.01x current ratio provides runway for operations.

What are the risks of investing in MDGL?

Claude: Severe profitability crisis: -$288.3M net loss and -$30.1% net margin indicate the company is unprofitable at scale. Negative free cash flow of -$190M annually is unsustainable without capital raises or achieving profitability.

What is MDGL's revenue and growth?

MADRIGAL PHARMACEUTICALS, INC. reported revenue of $958.4M.

Does MDGL pay dividends?

MADRIGAL PHARMACEUTICALS, INC. does not currently pay dividends.

Where can I find MDGL SEC filings?

Official SEC filings for MADRIGAL PHARMACEUTICALS, INC. (CIK: 0001157601) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is MDGL's EPS?

MADRIGAL PHARMACEUTICALS, INC. has a diluted EPS of $-12.85.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is MDGL a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, MADRIGAL PHARMACEUTICALS, INC. has a SELL rating with 85% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is MDGL stock overvalued or undervalued?

Valuation metrics for MDGL: ROE of -47.8% (sector avg: 15%), net margin of -30.1% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy MDGL stock in 2026?

Our dual AI analysis gives MADRIGAL PHARMACEUTICALS, INC. a combined SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is MDGL's free cash flow?

MADRIGAL PHARMACEUTICALS, INC.'s operating cash flow is $-189.6M, with capital expenditures of $467.0K. FCF margin is -19.8%.

How does MDGL compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -30.1% (avg: 12%), ROE -47.8% (avg: 15%), current ratio 4.01 (avg: 2).

Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 1, 2026 | Data as of: 2025-12-31 | Powered by Claude AI