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Halozyme Therapeutics, Inc.. (HALO) Stock Fundamental Analysis & AI Rating 2026

HALO Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001159036
Updated This Month • Analysis: May 12, 2026 • SEC Data: 2026-03-31
Combined AI Rating
HOLD
64% Confidence
NEUTRAL
SELL
58% Conf
BUY
70% Conf

📊 HALO Key Takeaways

Revenue: $376.7M
Net Margin: 39.8%
Free Cash Flow: $176.3M
Current Ratio: 2.76x
Debt/Equity: 8.81x
EPS: $1.22
AI Rating: SELL with 58% confidence
Halozyme Therapeutics, Inc.. (HALO) receives a HOLD rating with 64% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $376.7M, net profit margin of 39.8%, and return on equity (ROE) of 68.3%, Halozyme Therapeutics, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete HALO stock analysis for 2026.

Is Halozyme Therapeutics, Inc.. (HALO) a Good Investment?

Claude

HaloZyme demonstrates strong 37.6% YoY revenue growth and exceptional free cash flow generation, but the 28.6% YoY decline in net income despite higher revenues indicates deteriorating earnings quality. The dangerously elevated 8.81x debt-to-equity ratio combined with an unsustainable 1.6% gross margin signals fundamental business model challenges and elevated financial risk.

ChatGPT

Revenue growth is strong and operating profitability with exceptional free cash flow conversion supports balance sheet flexibility despite heavy leverage. Liquidity and interest coverage are robust, though the YoY earnings decline and anomalously low gross margin signal mix/accounting volatility to monitor.

Why Buy Halozyme Therapeutics, Inc.. Stock? HALO Key Strengths

Claude
  • + Strong revenue growth of 37.6% YoY with $376.7M in sales
  • + Exceptional free cash flow generation of $176.3M with 46.8% FCF margin demonstrating strong cash conversion
  • + Robust liquidity and interest coverage with 2.76x current ratio and 40.9x interest coverage ratio
ChatGPT
  • + Strong top-line growth (+37.6% YoY) with high operating margin (33.6%)
  • + Exceptional free cash flow (46% margin) with minimal capex needs
  • + Solid liquidity (4.66x current) and very high interest coverage (104x)

HALO Stock Risks: Halozyme Therapeutics, Inc.. Investment Risks

Claude
  • ! Net income declined 28.6% YoY and EPS fell 25.4% despite strong revenue growth, indicating poor earnings quality and unsustainable business model
  • ! Critically high debt-to-equity ratio of 8.81x ($1.9B debt vs. $219.6M equity) creates substantial financial leverage risk and limits operational flexibility
  • ! Exceptionally low gross margin of 1.6% is unsustainable and suggests fundamental cost structure or competitive pressures that threaten long-term profitability
ChatGPT
  • ! High leverage and thin equity (Debt/Equity 43.9x) raise refinancing/covenant risk
  • ! Net income and EPS down YoY despite growth, indicating margin/expense volatility
  • ! Extremely low reported gross margin (0.4%) suggests mix or accounting anomalies that could compress profitability if persistent

Key Metrics to Watch

Claude
  • * Gross margin trend and revenue composition drivers - unsustainable 1.6% margin must improve
  • * Debt-to-equity ratio and long-term debt levels - 8.81x leverage is dangerously high for declining profitability
  • * Operating cash flow sustainability and net income recovery - critical divergence between top-line growth and bottom-line performance must reverse
ChatGPT
  • * Free cash flow (FCF) margin
  • * Interest coverage

Halozyme Therapeutics, Inc.. (HALO) Financial Metrics & Key Ratios

Revenue
$376.7M
Net Income
$150.0M
EPS (Diluted)
$1.22
Free Cash Flow
$176.3M
Total Assets
$2.7B
Cash Position
$309.7M

💡 AI Analyst Insight

The 46.8% free cash flow margin provides substantial flexibility for dividends, buybacks, and strategic investments. Strong liquidity with a 2.76x current ratio provides a solid financial cushion.

HALO Profit Margin, ROE & Profitability Analysis

Gross Margin 1.6%
Operating Margin 49.0%
Net Margin 39.8%
ROE 68.3%
ROA 5.6%
FCF Margin 46.8%

HALO vs Healthcare Sector: How Halozyme Therapeutics, Inc.. Compares

How Halozyme Therapeutics, Inc.. compares to Healthcare sector averages

Net Margin
HALO 39.8%
vs
Sector Avg 12.0%
HALO Sector
ROE
HALO 68.3%
vs
Sector Avg 15.0%
HALO Sector
Current Ratio
HALO 2.8x
vs
Sector Avg 2.0x
HALO Sector
Debt/Equity
HALO 8.8x
vs
Sector Avg 0.6x
HALO Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Halozyme Therapeutics, Inc.. Stock Overvalued? HALO Valuation Analysis 2026

Based on fundamental analysis, Halozyme Therapeutics, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
68.3%
Sector avg: 15%
Net Profit Margin
39.8%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
8.81x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Halozyme Therapeutics, Inc.. Balance Sheet: HALO Debt, Cash & Liquidity

Current Ratio
2.76x
Quick Ratio
2.33x
Debt/Equity
8.81x
Debt/Assets
91.8%
Interest Coverage
40.94x
Long-term Debt
$1.9B

HALO Revenue & Earnings Growth: 5-Year Financial Trend

HALO 5-year financial data: Year 2021: Revenue $443.3M, Net Income -$72.2M, EPS $-0.50. Year 2022: Revenue $660.1M, Net Income $129.1M, EPS $0.91. Year 2023: Revenue $829.3M, Net Income $402.7M, EPS $2.74. Year 2024: Revenue $1.0B, Net Income $202.1M, EPS $1.44. Year 2025: Revenue $1.4B, Net Income $281.6M, EPS $2.10.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Halozyme Therapeutics, Inc..'s revenue has grown significantly by 215% over the 5-year period, indicating strong business expansion. The most recent EPS of $2.10 reflects profitable operations.

HALO Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
46.8%
Free cash flow / Revenue

HALO Quarterly Earnings & Performance

Quarterly financial performance data for Halozyme Therapeutics, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $264.9M $118.1M $0.93
Q3 2025 $290.1M $137.0M $1.05
Q2 2025 $231.4M $93.2M $0.72
Q1 2025 $195.9M $76.8M $0.60
Q3 2024 $216.0M $81.8M $0.61
Q2 2024 $221.0M $74.8M $0.56
Q1 2024 $162.1M $39.6M $0.29
Q3 2023 $209.0M $61.6M $0.44

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Halozyme Therapeutics, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$180.1M
Cash generated from operations
Stock Buybacks
$342.4M
Shares repurchased (TTM)
Capital Expenditures
$3.7M
Investment in assets
Dividends
None
No dividend program

HALO SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Halozyme Therapeutics, Inc.. (CIK: 0001159036)

📋 Recent SEC Filings

Date Form Document Action
May 13, 2026 4 xslF345X06/wk-form4_1778709013.xml View →
May 11, 2026 10-Q halo-20260331.htm View →
May 11, 2026 8-K halo-20260511.htm View →
May 7, 2026 4 xslF345X06/wk-form4_1778195074.xml View →
May 7, 2026 4 xslF345X06/wk-form4_1778195038.xml View →

Frequently Asked Questions about HALO

What is the AI rating for HALO?

Halozyme Therapeutics, Inc.. (HALO) has a Combined AI Rating of HOLD from Claude (SELL) and ChatGPT (BUY) with 64% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are HALO's key strengths?

Claude: Strong revenue growth of 37.6% YoY with $376.7M in sales. Exceptional free cash flow generation of $176.3M with 46.8% FCF margin demonstrating strong cash conversion. ChatGPT: Strong top-line growth (+37.6% YoY) with high operating margin (33.6%). Exceptional free cash flow (46% margin) with minimal capex needs.

What are the risks of investing in HALO?

Claude: Net income declined 28.6% YoY and EPS fell 25.4% despite strong revenue growth, indicating poor earnings quality and unsustainable business model. Critically high debt-to-equity ratio of 8.81x ($1.9B debt vs. $219.6M equity) creates substantial financial leverage risk and limits operational flexibility. ChatGPT: High leverage and thin equity (Debt/Equity 43.9x) raise refinancing/covenant risk. Net income and EPS down YoY despite growth, indicating margin/expense volatility.

What is HALO's revenue and growth?

Halozyme Therapeutics, Inc.. reported revenue of $376.7M.

Does HALO pay dividends?

Halozyme Therapeutics, Inc.. does not currently pay dividends.

Where can I find HALO SEC filings?

Official SEC filings for Halozyme Therapeutics, Inc.. (CIK: 0001159036) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is HALO's EPS?

Halozyme Therapeutics, Inc.. has a diluted EPS of $1.22.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is HALO a good stock to buy right now?

Based on our AI fundamental analysis in May 2026, Halozyme Therapeutics, Inc.. has a HOLD rating with 64% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is HALO stock overvalued or undervalued?

Valuation metrics for HALO: ROE of 68.3% (sector avg: 15%), net margin of 39.8% (sector avg: 12%). Higher ROE suggests strong returns relative to peers.

Should I buy HALO stock in 2026?

Our dual AI analysis gives Halozyme Therapeutics, Inc.. a combined HOLD rating for 2026. Revenue is data pending, with profitability above sector average. Always conduct your own research.

What is HALO's free cash flow?

Halozyme Therapeutics, Inc..'s operating cash flow is $180.1M, with capital expenditures of $3.7M. FCF margin is 46.8%.

How does HALO compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin 39.8% (avg: 12%), ROE 68.3% (avg: 15%), current ratio 2.76 (avg: 2).

Is Halozyme Therapeutics, Inc.. carrying too much debt?

HALO has a debt-to-equity ratio of 8.81x, which is above the Healthcare sector average of 0.6x. However, the current ratio of 2.76 suggests adequate short-term liquidity.

Why is HALO's return on equity (ROE) so high?

Halozyme Therapeutics, Inc.. has a return on equity of 68.3%, significantly above the Healthcare sector average of 15%. A high ROE indicates the company is efficient at generating profits from shareholder equity. This is supported by a 39.8% net margin.

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 12, 2026 | Data as of: 2026-03-31 | Powered by Claude AI