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Gyre Therapeutics, Inc.. (GYRE) Stock Fundamental Analysis & AI Rating 2026

GYRE Nasdaq Pharmaceutical Preparations DE CIK: 0001124105
Updated This Month • Analysis: May 10, 2026 • SEC Data: 2026-03-31
Combined AI Rating
HOLD
64% Confidence
STRONG AGREEMENT
HOLD
65% Conf
HOLD
64% Conf

📊 GYRE Key Takeaways

Revenue: $22.5M
Net Margin: -43.8%
Free Cash Flow: $3.0M
Current Ratio: 4.64x
Debt/Equity: 0.00x
EPS: $-0.10
AI Rating: HOLD with 65% confidence
Gyre Therapeutics, Inc.. (GYRE) receives a HOLD rating with 64% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $22.5M, net profit margin of -43.8%, and return on equity (ROE) of -9.7%, Gyre Therapeutics, Inc.. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete GYRE stock analysis for 2026.

Is Gyre Therapeutics, Inc.. (GYRE) a Good Investment?

Claude

Early-stage pharmaceutical company with exceptional 6573% revenue growth and fortress balance sheet ($37.5M cash, zero debt), but concerning data quality issues (impossible 336% gross margin), persistent operating losses, and typical pharma execution risks create uncertainty pending clarification of financial metrics.

ChatGPT

GYRE shows a dramatic shift to profitability on surging revenue and a robust 64.9% gross margin, supported by a debt-free, highly liquid balance sheet. However, weak cash conversion (slightly negative FCF) and a sharp EPS decline suggest dilution and potential revenue quality concerns. Maintain neutral until the company demonstrates consistent, cash-generative growth with sustainable margins.

Why Buy Gyre Therapeutics, Inc.. Stock? GYRE Key Strengths

Claude
  • + Exceptional 6573% YoY revenue growth indicating successful commercialization or product approval
  • + Fortress balance sheet with $37.5M cash, zero long-term debt, and 4.64x current ratio providing operational runway
  • + Positive free cash flow ($3.0M) and operating cash flow despite net losses demonstrates efficient cash deployment
ChatGPT
  • + Debt-free with strong liquidity (5.6x current ratio, $37M cash)
  • + High gross margin and positive operating/net income
  • + Significant revenue growth with improving ROE/ROA

GYRE Stock Risks: Gyre Therapeutics, Inc.. Investment Risks

Claude
  • ! Impossible gross margin (336%) suggests data quality issues, one-time gains, or accounting complexity requiring clarification
  • ! Operating losses of $9.4M and -41.5% operating margin indicate company requires significant revenue scale to achieve profitability
  • ! Pharmaceutical sector inherent risks including clinical failure, regulatory rejection, competitive dynamics, and long development timelines
ChatGPT
  • ! Weak cash generation despite profits (negative FCF, low OCF)
  • ! Dilution risk signaled by 60% YoY EPS decline
  • ! Potential one-time or non-recurring revenue driving growth and margins

Key Metrics to Watch

Claude
  • * Gross margin normalization and clarification of 336% calculation source
  • * Operating margin trajectory and cash burn rate sustainability with current revenue base
  • * Path to operating profitability and clinical pipeline advancement through regulatory milestones
ChatGPT
  • * Operating cash flow margin (cash conversion)
  • * Gross margin trend

Gyre Therapeutics, Inc.. (GYRE) Financial Metrics & Key Ratios

Revenue
$22.5M
Net Income
$-9.9M
EPS (Diluted)
$-0.10
Free Cash Flow
$3.0M
Total Assets
$162.0M
Cash Position
$37.5M

💡 AI Analyst Insight

Strong liquidity with a 4.64x current ratio provides a solid financial cushion.

GYRE Profit Margin, ROE & Profitability Analysis

Gross Margin 336.2%
Operating Margin -41.5%
Net Margin -43.8%
ROE -9.7%
ROA -6.1%
FCF Margin 13.3%

GYRE vs Healthcare Sector: How Gyre Therapeutics, Inc.. Compares

How Gyre Therapeutics, Inc.. compares to Healthcare sector averages

Net Margin
GYRE -43.8%
vs
Sector Avg 12.0%
GYRE Sector
ROE
GYRE -9.7%
vs
Sector Avg 15.0%
GYRE Sector
Current Ratio
GYRE 4.6x
vs
Sector Avg 2.0x
GYRE Sector
Debt/Equity
GYRE 0.0x
vs
Sector Avg 0.6x
GYRE Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Gyre Therapeutics, Inc.. Stock Overvalued? GYRE Valuation Analysis 2026

Based on fundamental analysis, Gyre Therapeutics, Inc.. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-9.7%
Sector avg: 15%
Net Profit Margin
-43.8%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Gyre Therapeutics, Inc.. Balance Sheet: GYRE Debt, Cash & Liquidity

Current Ratio
4.64x
Quick Ratio
4.06x
Debt/Equity
0.00x
Debt/Assets
15.4%
Interest Coverage
-6.33x
Long-term Debt
$0.0

GYRE Revenue & Earnings Growth: 5-Year Financial Trend

GYRE 5-year financial data: Year 2020: Revenue $20.9M, Net Income N/A, EPS N/A. Year 2021: Revenue $20.9M, Net Income -$56.2M, EPS N/A. Year 2023: Revenue $113.5M, Net Income $4.3M, EPS $0.03. Year 2024: Revenue $113.5M, Net Income -$85.5M, EPS $-1.41. Year 2025: Revenue $116.6M, Net Income $17.9M, EPS $0.05.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Gyre Therapeutics, Inc..'s revenue has grown significantly by 457% over the 5-year period, indicating strong business expansion. The most recent EPS of $0.05 reflects profitable operations.

GYRE Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
13.3%
Free cash flow / Revenue

GYRE Quarterly Earnings & Performance

Quarterly financial performance data for Gyre Therapeutics, Inc.. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q1 2026 $22.1M $3.7M $0.00
Q3 2025 $25.5M $1.6M $0.01
Q2 2025 $25.2M $1.6M $0.00
Q1 2025 $22.1M $3.7M $0.00
Q3 2024 $25.5M $2.9M $0.01
Q2 2024 $25.2M $3.8M $0.01
Q1 2024 $24.9M $4.2M $0.03
Q1 2022 $794.0K -$14.5M N/A

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Gyre Therapeutics, Inc.. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
$3.2M
Cash generated from operations
Stock Buybacks
$82.0K
Shares repurchased (TTM)
Capital Expenditures
$178.0K
Investment in assets
Dividends Paid
$12.8M
Returned to shareholders

GYRE SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Gyre Therapeutics, Inc.. (CIK: 0001124105)

📋 Recent SEC Filings

Date Form Document Action
May 22, 2026 4 xslF345X06/form4.xml View →
May 20, 2026 4 xslF345X06/form4.xml View →
May 20, 2026 4 xslF345X06/form4.xml View →
May 18, 2026 4 xslF345X06/form4.xml View →
May 14, 2026 8-K ef20073544_8k.htm View →

Frequently Asked Questions about GYRE

What is the AI rating for GYRE?

Gyre Therapeutics, Inc.. (GYRE) has a Combined AI Rating of HOLD from Claude (HOLD) and ChatGPT (HOLD) with 64% combined confidence, based on fundamental analysis of SEC EDGAR filings.

What are GYRE's key strengths?

Claude: Exceptional 6573% YoY revenue growth indicating successful commercialization or product approval. Fortress balance sheet with $37.5M cash, zero long-term debt, and 4.64x current ratio providing operational runway. ChatGPT: Debt-free with strong liquidity (5.6x current ratio, $37M cash). High gross margin and positive operating/net income.

What are the risks of investing in GYRE?

Claude: Impossible gross margin (336%) suggests data quality issues, one-time gains, or accounting complexity requiring clarification. Operating losses of $9.4M and -41.5% operating margin indicate company requires significant revenue scale to achieve profitability. ChatGPT: Weak cash generation despite profits (negative FCF, low OCF). Dilution risk signaled by 60% YoY EPS decline.

What is GYRE's revenue and growth?

Gyre Therapeutics, Inc.. reported revenue of $22.5M.

Does GYRE pay dividends?

Gyre Therapeutics, Inc.. pays dividends, with $12.8M distributed to shareholders in the trailing twelve months.

Where can I find GYRE SEC filings?

Official SEC filings for Gyre Therapeutics, Inc.. (CIK: 0001124105) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is GYRE's EPS?

Gyre Therapeutics, Inc.. has a diluted EPS of $-0.10.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is GYRE a good stock to buy right now?

Based on our AI fundamental analysis in May 2026, Gyre Therapeutics, Inc.. has a HOLD rating with 64% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is GYRE stock overvalued or undervalued?

Valuation metrics for GYRE: ROE of -9.7% (sector avg: 15%), net margin of -43.8% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy GYRE stock in 2026?

Our dual AI analysis gives Gyre Therapeutics, Inc.. a combined HOLD rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is GYRE's free cash flow?

Gyre Therapeutics, Inc..'s operating cash flow is $3.2M, with capital expenditures of $178.0K. FCF margin is 13.3%.

How does GYRE compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -43.8% (avg: 12%), ROE -9.7% (avg: 15%), current ratio 4.64 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: May 10, 2026 | Data as of: 2026-03-31 | Powered by Claude AI