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CRBU Stock Analysis - Caribou Biosciences, Inc. AI Rating

CRBU Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001619856
Recently Updated • Analysis: Mar 22, 2026 • SEC Data: 2025-12-31
AI Rating
STRONG SELL
92% Confidence

📊 CRBU Key Takeaways

Revenue: $11.2M
Net Margin: -1,327.4%
Free Cash Flow: $-112.4M
Current Ratio: 5.71x
Debt/Equity: 0.00x
EPS: $-1.59
AI Rating: STRONG SELL with 92% confidence

Investment Thesis

Caribou Biosciences is a pre-revenue clinical-stage biotech company with severe operating losses and massive cash burn that far exceeds revenue generation. With only $12.4M in cash against $111M annual operating cash burn, the company faces critical liquidity constraints and will require significant capital raises or major clinical success to avoid financial distress within 12 months.

CRBU Strengths

  • + Strong balance sheet with $122.2M stockholders equity provides substantial capital base
  • + Excellent liquidity position with 5.71x current ratio indicating near-term payment capability
  • + Zero long-term debt eliminates refinancing risk and interest burden
  • + Revenue growth of 11.7% YoY shows emerging commercial activity from R&D programs

CRBU Risks

  • ! Catastrophic cash burn of $111M annually against only $12.4M cash reserves indicates 1.3 months of runway at current burn rate
  • ! Operating losses of $148.3M on $11.2M revenue demonstrates completely unprofitable operations with losses 1,329% of revenue
  • ! Pre-commercial biotech model creates absolute dependence on clinical trial success and future funding; single negative trial result could be fatal
  • ! Negative free cash flow of $112.4M combined with minimal revenue makes the company entirely dependent on capital markets for survival
  • ! High insider trading activity (14 Form 4 filings in 90 days) may indicate uncertainty or management exit timing concerns

Key Metrics to Watch

CRBU Financial Metrics

Revenue
$11.2M
Net Income
$-148.1M
EPS (Diluted)
$-1.59
Free Cash Flow
$-112.4M
Total Assets
$175.4M
Cash Position
$12.4M

💡 AI Analyst Insight

Strong liquidity with a 5.71x current ratio provides a solid financial cushion.

CRBU Profitability Ratios

Gross Margin N/A
Operating Margin -1,329.4%
Net Margin -1,327.4%
ROE -121.2%
ROA -84.5%
FCF Margin -1,006.8%

CRBU vs Healthcare Sector

How Caribou Biosciences, Inc. compares to Healthcare sector averages

Net Margin
CRBU -1,327.4%
vs
Sector Avg 12.0%
CRBU Sector
ROE
CRBU -121.2%
vs
Sector Avg 15.0%
CRBU Sector
Current Ratio
CRBU 5.7x
vs
Sector Avg 2.0x
CRBU Sector
Debt/Equity
CRBU 0.0x
vs
Sector Avg 0.6x
CRBU Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

CRBU Balance Sheet & Liquidity

Current Ratio
5.71x
Quick Ratio
5.71x
Debt/Equity
0.00x
Debt/Assets
30.3%
Interest Coverage
N/A
Long-term Debt
N/A

CRBU 5-Year Financial Trend

CRBU 5-year financial data: Year 2021: Revenue $12.4M, Net Income -$23.4M, EPS N/A. Year 2022: Revenue $13.9M, Net Income -$66.9M, EPS $-2.11. Year 2023: Revenue $34.5M, Net Income -$99.4M, EPS $-1.64. Year 2024: Revenue $34.5M, Net Income -$102.1M, EPS $-1.38. Year 2025: Revenue $11.2M, Net Income -$149.1M, EPS $-1.65.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Caribou Biosciences, Inc.'s revenue has remained relatively flat over the 5-year period, with a 10% decline. The most recent EPS of $-1.65 indicates the company is currently unprofitable.

CRBU Growth Metrics (YoY)

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-1,006.8%
Free cash flow / Revenue

CRBU Quarterly Performance

Quarterly financial performance data for Caribou Biosciences, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 $2.0M -$27.5M $-0.30
Q2 2025 $2.7M -$37.7M $-0.42
Q1 2025 $2.4M -$40.0M $-0.43
Q3 2024 $2.0M -$10.0M $-0.12
Q2 2024 $3.5M -$28.0M $-0.42
Q1 2024 $2.4M -$28.0M $-0.46
Q3 2023 $3.3M -$10.0M $-0.12
Q2 2023 $3.8M -$19.1M $-0.44

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

CRBU Capital Allocation

Operating Cash Flow
-$111.0M
Cash generated from operations
Capital Expenditures
$1.4M
Investment in assets
Dividends
None
No dividend program

CRBU SEC Filings

Access official SEC EDGAR filings for Caribou Biosciences, Inc. (CIK: 0001619856)

📋 Recent SEC Filings

Date Form Document Action
Mar 5, 2026 10-K crbu-20251231.htm View →
Mar 5, 2026 8-K crbu-20260305.htm View →
Feb 27, 2026 4 xslF345X05/wk-form4_1772226070.xml View →
Feb 24, 2026 4 xslF345X05/wk-form4_1771984478.xml View →
Feb 24, 2026 4 xslF345X05/wk-form4_1771984473.xml View →

Frequently Asked Questions about CRBU

What is the AI rating for CRBU?

Caribou Biosciences, Inc. (CRBU) has an AI rating of STRONG SELL with 92% confidence, based on fundamental analysis of SEC EDGAR filings.

What are CRBU's key strengths?

Strong balance sheet with $122.2M stockholders equity provides substantial capital base. Excellent liquidity position with 5.71x current ratio indicating near-term payment capability.

What are the risks of investing in CRBU?

Catastrophic cash burn of $111M annually against only $12.4M cash reserves indicates 1.3 months of runway at current burn rate. Operating losses of $148.3M on $11.2M revenue demonstrates completely unprofitable operations with losses 1,329% of revenue.

What is CRBU's revenue and growth?

Caribou Biosciences, Inc. reported revenue of $11.2M.

Does CRBU pay dividends?

Caribou Biosciences, Inc. does not currently pay dividends.

Where can I find CRBU SEC filings?

Official SEC filings for Caribou Biosciences, Inc. (CIK: 0001619856) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CRBU's EPS?

Caribou Biosciences, Inc. has a diluted EPS of $-1.59.

How is the AI analysis conducted?

Our AI (Claude) analyzes publicly available SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports to evaluate financial health, profitability ratios, balance sheet strength, and growth metrics.

Disclaimer: This analysis is generated by Claude AI based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 22, 2026 | Data as of: 2025-12-31 | Powered by Claude AI