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CNTA Stock Analysis - Centessa Pharmaceuticals plc AI Rating

CNTA Nasdaq Pharmaceutical Preparations X0 CIK: 0001847903
Recently Updated • Analysis: Mar 22, 2026 • SEC Data: 2025-09-30
AI Rating
STRONG SELL
92% Confidence

📊 CNTA Key Takeaways

Revenue: $15.0M
Net Margin: -875.8%
Free Cash Flow: $-138.4M
Current Ratio: 10.57x
Debt/Equity: 0.36x
EPS: $-0.98
AI Rating: STRONG SELL with 92% confidence

Investment Thesis

Centessa is a clinical-stage biopharmaceutical company with severe financial distress, burning through $138M in operating cash annually with only $50.8M in cash reserves, providing minimal runway. The company generated negligible revenue ($15M, down 100% YoY) while operating losses exceeded $139M, indicating it is far from commercialization. With negative operating margins of -928% and free cash flow of -$138.4M, the company faces existential solvency risk without immediate capital raises or transformative value creation.

CNTA Strengths

  • + Strong balance sheet composition with $301.6M stockholders' equity and low debt/equity ratio of 0.36x, reducing bankruptcy risk from leverage
  • + Excellent current and quick ratios (10.57x) indicating sufficient short-term liquidity to meet immediate obligations
  • + Early-stage pharmaceutical pipeline positioning with 11 Form 4 insider filings suggesting ongoing management activity

CNTA Risks

  • ! Catastrophic cash burn rate of $138M annually with only $50.8M cash reserves, indicating less than 5 months of runway at current burn rate
  • ! Complete revenue collapse (down 100% YoY) with only $15M recognized, demonstrating failure of commercial efforts or product discontinuation
  • ! Massive operating losses with -928% operating margin and -875% net margin indicating business model is fundamentally broken and unprofitable at scale
  • ! Negative interest coverage ratio of -55x reflects inability to service debt from operations; dependent on cash reserves and capital markets
  • ! Pre-commercial pharmaceutical company facing typical clinical development risk with no approved commercial products generating meaningful revenue

Key Metrics to Watch

CNTA Financial Metrics

Revenue
$15.0M
Net Income
$-131.4M
EPS (Diluted)
$-0.98
Free Cash Flow
$-138.4M
Total Assets
$448.3M
Cash Position
$50.8M

💡 AI Analyst Insight

Strong liquidity with a 10.57x current ratio provides a solid financial cushion.

CNTA Profitability Ratios

Gross Margin N/A
Operating Margin -928.1%
Net Margin -875.8%
ROE -43.6%
ROA -29.3%
FCF Margin -922.5%

CNTA vs Healthcare Sector

How Centessa Pharmaceuticals plc compares to Healthcare sector averages

Net Margin
CNTA -875.8%
vs
Sector Avg 12.0%
CNTA Sector
ROE
CNTA -43.6%
vs
Sector Avg 15.0%
CNTA Sector
Current Ratio
CNTA 10.6x
vs
Sector Avg 2.0x
CNTA Sector
Debt/Equity
CNTA 0.4x
vs
Sector Avg 0.6x
CNTA Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

CNTA Balance Sheet & Liquidity

Current Ratio
10.57x
Quick Ratio
10.57x
Debt/Equity
0.36x
Debt/Assets
32.7%
Interest Coverage
-55.05x
Long-term Debt
$109.8M

CNTA 5-Year Financial Trend

CNTA 5-year financial data: Year 2023: Revenue $6.9M, Net Income -$216.2M, EPS $-2.31. Year 2024: Revenue $6.9M, Net Income -$151.1M, EPS $-1.57.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Centessa Pharmaceuticals plc's revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-1.57 indicates the company is currently unprofitable.

CNTA Growth Metrics (YoY)

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-922.5%
Free cash flow / Revenue

CNTA Quarterly Performance

Quarterly financial performance data for Centessa Pharmaceuticals plc including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 N/A -$42.6M $-0.37
Q2 2025 N/A -$43.8M $-0.38
Q1 2025 N/A -$26.1M $-0.20

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

CNTA Capital Allocation

Operating Cash Flow
-$138.0M
Cash generated from operations
Stock Buybacks
$12.0K
Shares repurchased (TTM)
Capital Expenditures
$360.0K
Investment in assets
Dividends
None
No dividend program

CNTA SEC Filings

Access official SEC EDGAR filings for Centessa Pharmaceuticals plc (CIK: 0001847903)

📋 Recent SEC Filings

Date Form Document Action
Mar 18, 2026 4 xslF345X06/wk-form4_1773873807.xml View →
Mar 13, 2026 4 xslF345X05/wk-form4_1773440606.xml View →
Mar 13, 2026 4 xslF345X05/wk-form4_1773440573.xml View →
Feb 13, 2026 8-K d932267d8k.htm View →
Feb 3, 2026 4 xslF345X05/wk-form4_1770163434.xml View →

Frequently Asked Questions about CNTA

What is the AI rating for CNTA?

Centessa Pharmaceuticals plc (CNTA) has an AI rating of STRONG SELL with 92% confidence, based on fundamental analysis of SEC EDGAR filings.

What are CNTA's key strengths?

Strong balance sheet composition with $301.6M stockholders' equity and low debt/equity ratio of 0.36x, reducing bankruptcy risk from leverage. Excellent current and quick ratios (10.57x) indicating sufficient short-term liquidity to meet immediate obligations.

What are the risks of investing in CNTA?

Catastrophic cash burn rate of $138M annually with only $50.8M cash reserves, indicating less than 5 months of runway at current burn rate. Complete revenue collapse (down 100% YoY) with only $15M recognized, demonstrating failure of commercial efforts or product discontinuation.

What is CNTA's revenue and growth?

Centessa Pharmaceuticals plc reported revenue of $15.0M.

Does CNTA pay dividends?

Centessa Pharmaceuticals plc does not currently pay dividends.

Where can I find CNTA SEC filings?

Official SEC filings for Centessa Pharmaceuticals plc (CIK: 0001847903) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is CNTA's EPS?

Centessa Pharmaceuticals plc has a diluted EPS of $-0.98.

How is the AI analysis conducted?

Our AI (Claude) analyzes publicly available SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports to evaluate financial health, profitability ratios, balance sheet strength, and growth metrics.

Disclaimer: This analysis is generated by Claude AI based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 22, 2026 | Data as of: 2025-09-30 | Powered by Claude AI