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Senti Biosciences, Inc. (SNTI) Stock Fundamental Analysis & AI Rating 2026

SNTI Nasdaq Biological Products, (No Diagnostic Substances) DE CIK: 0001854270
Recently Updated • Analysis: Apr 16, 2026 • SEC Data: 2025-12-31
STRONG SELL
88% Conf
Pending
Analysis scheduled

📊 SNTI Key Takeaways

Revenue: $22.0K
Net Margin: -279,263.6%
Free Cash Flow: $-43.6M
Current Ratio: 1.67x
Debt/Equity: 0.00x
EPS: $-2.73
AI Rating: STRONG SELL with 88% confidence
Senti Biosciences, Inc. (SNTI) receives a STRONG SELL rating with 88% confidence from our AI fundamental analysis based on SEC 10-K filings. With revenue of $22.0K, net profit margin of -279,263.6%, and return on equity (ROE) of -1,099.3%, Senti Biosciences, Inc. demonstrates mixed fundamentals in the Healthcare sector. Below is our complete SNTI stock analysis for 2026.

Is Senti Biosciences, Inc. (SNTI) a Good Investment?

Claude

Senti Biosciences is a pre-revenue biotech company with severe cash burn and critically limited runway. Operating losses of $68.8M against only $22K in revenue, combined with $43.4M in annual operating cash outflows against $16.4M in cash reserves, indicates insolvency risk within 4-5 months without additional financing. The company exhibits classic early-stage biotech risk with no demonstrated path to profitability.

Why Buy Senti Biosciences, Inc. Stock? SNTI Key Strengths

Claude
  • + Zero long-term debt reduces financial leverage risk
  • + Current ratio of 1.67x indicates adequate short-term liquidity position
  • + Biological products sector offers high growth potential if pipeline succeeds

SNTI Stock Risks: Senti Biosciences, Inc. Investment Risks

Claude
  • ! Critical cash runway of approximately 4-5 months at current $43.4M annual burn rate
  • ! Minimal revenue ($22K) with massive operating losses indicates no near-term commercialization
  • ! Stockholders equity of only $5.6M provides minimal buffer; liabilities of $45.6M threaten equity value
  • ! Will require dilutive equity financing to survive, destroying shareholder value
  • ! Early-stage biotech with high probability of clinical/commercial failure

Key Metrics to Watch

Claude
  • * Monthly cash burn rate and cash runway remaining
  • * Financing announcements and dilution impact
  • * Clinical trial progress and pipeline advancement milestones

Senti Biosciences, Inc. (SNTI) Financial Metrics & Key Ratios

Revenue
$22.0K
Net Income
$-61.4M
EPS (Diluted)
$-2.73
Free Cash Flow
$-43.6M
Total Assets
$51.2M
Cash Position
$16.4M

💡 AI Analyst Insight

Senti Biosciences, Inc. presents a mixed fundamental picture. Review the detailed metrics above to form your own investment thesis.

SNTI Profit Margin, ROE & Profitability Analysis

Gross Margin N/A
Operating Margin -312,631.8%
Net Margin -279,263.6%
ROE -1,099.3%
ROA -119.9%
FCF Margin -198,363.6%

SNTI vs Healthcare Sector: How Senti Biosciences, Inc. Compares

How Senti Biosciences, Inc. compares to Healthcare sector averages

Net Margin
SNTI -279,263.6%
vs
Sector Avg 12.0%
SNTI Sector
ROE
SNTI -1,099.3%
vs
Sector Avg 15.0%
SNTI Sector
Current Ratio
SNTI 1.7x
vs
Sector Avg 2.0x
SNTI Sector
Debt/Equity
SNTI 0.0x
vs
Sector Avg 0.6x
SNTI Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is Senti Biosciences, Inc. Stock Overvalued? SNTI Valuation Analysis 2026

Based on fundamental analysis, Senti Biosciences, Inc. has mixed fundamental signals relative to the Healthcare sector in 2026.

Return on Equity
-1,099.3%
Sector avg: 15%
Net Profit Margin
-279,263.6%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
0.00x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

Senti Biosciences, Inc. Balance Sheet: SNTI Debt, Cash & Liquidity

Current Ratio
1.67x
Quick Ratio
1.67x
Debt/Equity
0.00x
Debt/Assets
89.1%
Interest Coverage
N/A
Long-term Debt
N/A

SNTI Revenue & Earnings Growth: 5-Year Financial Trend

SNTI 5-year financial data: Year 2022: Revenue $3.3M, Net Income -$55.3M, EPS $-19.00. Year 2023: Revenue $3.3M, Net Income -$58.2M, EPS $-2.23. Year 2024: Revenue $2.0M, Net Income -$71.1M, EPS $-16.01. Year 2025: Revenue $22.0K, Net Income -$52.8M, EPS $-12.03.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Senti Biosciences, Inc.'s revenue has declined by 99% over the 5-year period, indicating business contraction. The most recent EPS of $-12.03 indicates the company is currently unprofitable.

SNTI Revenue Growth, EPS Growth & YoY Performance

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-198,363.6%
Free cash flow / Revenue

SNTI Quarterly Earnings & Performance

Quarterly financial performance data for Senti Biosciences, Inc. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2024 N/A -$11.2M $-3.36
Q2 2024 N/A -$11.2M $-2.45
Q1 2024 N/A -$12.1M $-0.26
Q3 2023 $255.0K -$11.6M $-0.34
Q2 2023 $687.0K -$11.6M $-0.42
Q1 2023 $854.0K -$11.8M $-0.42
Q3 2022 $926.0K -$11.4M $-0.38
Q2 2022 $778.0K -$11.6M $-0.86

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

Senti Biosciences, Inc. Dividends, Buybacks & Capital Allocation

Operating Cash Flow
-$43.4M
Cash generated from operations
Capital Expenditures
$196.0K
Investment in assets
Dividends
None
No dividend program

SNTI SEC Filings: Latest 10-K & 10-Q Analysis

Access official SEC EDGAR filings for Senti Biosciences, Inc. (CIK: 0001854270)

📋 Recent SEC Filings

Date Form Document Action
Apr 1, 2026 8-K snti-20260401.htm View →
Mar 27, 2026 10-K snti-20251231.htm View →
Mar 27, 2026 8-K snti-20260327.htm View →
Mar 19, 2026 8-K snti-20260317.htm View →
Mar 11, 2026 4 xslF345X05/wk-form4_1773259312.xml View →

Frequently Asked Questions about SNTI

What is the AI rating for SNTI?

Senti Biosciences, Inc. (SNTI) has an AI rating of STRONG SELL with 88% confidence, based on fundamental analysis of SEC EDGAR filings.

What are SNTI's key strengths?

Claude: Zero long-term debt reduces financial leverage risk. Current ratio of 1.67x indicates adequate short-term liquidity position.

What are the risks of investing in SNTI?

Claude: Critical cash runway of approximately 4-5 months at current $43.4M annual burn rate. Minimal revenue ($22K) with massive operating losses indicates no near-term commercialization.

What is SNTI's revenue and growth?

Senti Biosciences, Inc. reported revenue of $22.0K.

Does SNTI pay dividends?

Senti Biosciences, Inc. does not currently pay dividends.

Where can I find SNTI SEC filings?

Official SEC filings for Senti Biosciences, Inc. (CIK: 0001854270) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is SNTI's EPS?

Senti Biosciences, Inc. has a diluted EPS of $-2.73.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is SNTI a good stock to buy right now?

Based on our AI fundamental analysis in April 2026, Senti Biosciences, Inc. has a STRONG SELL rating with 88% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is SNTI stock overvalued or undervalued?

Valuation metrics for SNTI: ROE of -1,099.3% (sector avg: 15%), net margin of -279,263.6% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy SNTI stock in 2026?

Our dual AI analysis gives Senti Biosciences, Inc. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is SNTI's free cash flow?

Senti Biosciences, Inc.'s operating cash flow is $-43.4M, with capital expenditures of $196.0K. FCF margin is -198,363.6%.

How does SNTI compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -279,263.6% (avg: 12%), ROE -1,099.3% (avg: 15%), current ratio 1.67 (avg: 2).

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Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Apr 16, 2026 | Data as of: 2025-12-31 | Powered by Claude AI