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APRE Stock Analysis - Aprea Therapeutics, Inc. AI Rating

APRE Nasdaq Pharmaceutical Preparations DE CIK: 0001781983
Analysis Date: Mar 20, 2026 | Data as of: 2025-12-31
AI Rating
STRONG SELL
85% Confidence

Investment Thesis

Aprea Therapeutics is a pre-revenue pharmaceutical company with severe cash burn and no near-term revenue generation, having consumed $12.9M in operating cash flow with only $14.6M in cash remaining. The company faces an acute liquidity crisis as current cash reserves provide less than 14 months of runway at current burn rates, with no clear path to profitability or revenue generation visible in the financial statements.

APRE Strengths

  • + Strong immediate liquidity position with $14.6M cash and 5.63x current ratio
  • + Minimal debt burden with zero long-term debt and 0.0x debt/equity ratio
  • + Recent insider activity with 4 Form 4 filings in last 90 days indicating some management engagement

APRE Risks

  • ! No revenue generation with operating losses of -$13.2M and negative operating margin indicating early-stage pre-commercial status
  • ! Severe cash burn rate of -$12.9M in operating cash flow with less than 14 months of cash runway at current rates
  • ! Negative returns on equity (-101.3%) and assets (-79.1%) demonstrate value destruction with no visible path to profitability
  • ! Pre-revenue pharmaceutical company faces extremely high clinical development and regulatory approval risk with unclear pipeline maturity

Key Metrics to Watch

APRE Financial Metrics

Revenue
N/A
Net Income
$-12.6M
EPS (Diluted)
$-1.93
Free Cash Flow
$-12.9M
Total Assets
$15.9M
Cash Position
$14.6M

APRE Profitability Ratios

Gross Margin N/A
Operating Margin N/A
Net Margin N/A
ROE -101.3%
ROA -79.1%
FCF Margin N/A

APRE Balance Sheet & Liquidity

Current Ratio
5.63x
Quick Ratio
5.63x
Debt/Equity
0.00x
Debt/Assets
24.8%
Interest Coverage
N/A
Long-term Debt
N/A

APRE 5-Year Financial Trend

APRE 5-year financial data:
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: Aprea Therapeutics, Inc.'s revenue has remained relatively flat over the 5-year period, with a 0% decline. The most recent EPS of $-2.35 indicates the company is currently unprofitable.

APRE Growth Metrics (YoY)

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
N/A
Free cash flow / Revenue

APRE Capital Allocation

Operating Cash Flow
-$12.9M
Cash generated from operations
Capital Expenditures
$15.5K
Investment in assets
Dividends
None
No dividend program

APRE SEC Filings

Access official SEC EDGAR filings for Aprea Therapeutics, Inc. (CIK: 0001781983)

Disclaimer: This analysis is generated by Claude AI based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 20, 2026 | Data as of: 2025-12-31 | Powered by Claude AI