← Back to All US Stocks

INO Stock Analysis 2026 - INOVIO PHARMACEUTICALS, INC. AI Rating

INO Nasdaq Pharmaceutical Preparations DE CIK: 0001055726
Recently Updated • Analysis: Mar 29, 2026 • SEC Data: 2025-12-31
STRONG SELL
92% Conf
Pending
Analysis scheduled

📊 INO Key Takeaways

Revenue: $65.3K
Net Margin: -130,000.0%
Free Cash Flow: $-88.9M
Current Ratio: 1.40x
Debt/Equity: 2.60x
EPS: $-1.81
AI Rating: STRONG SELL with 92% confidence

Is INO a Good Investment? Thesis Analysis

Claude

Inovio Pharmaceuticals faces severe financial distress with collapsing revenues (-70% YoY), massive operating losses (-$86.8M), and negative free cash flow (-$88.9M) indicating the company is burning cash at an unsustainable rate. The company's debt-to-equity ratio of 2.60x combined with only $44.3M in cash against $62.8M in long-term debt creates significant solvency risk, with current operational performance unable to cover debt service obligations.

Why Buy INO? Key Strengths

Claude
  • + Net loss improved 20.8% YoY suggesting margin stabilization from peak losses
  • + Current ratio of 1.40x provides adequate short-term liquidity cushion
  • + Positive insider activity with 9 Form 4 filings in last 90 days

INO Investment Risks to Consider

Claude
  • ! Revenue collapsed 70% YoY indicating loss of commercial traction or pipeline setback
  • ! Negative free cash flow of -$88.9M with only $44.3M cash on hand indicates runway of ~6 months at current burn rate
  • ! Debt-to-equity of 2.60x with negative interest coverage (-488.2x) creates imminent debt servicing crisis
  • ! Operating margin of -132,871% reflects extreme unprofitability with minimal revenue relative to operating expenses
  • ! Total liabilities exceed stockholders' equity by $26.1M indicating balance sheet impairment

Key Metrics to Watch

Claude
  • * Cash burn rate and months of cash runway remaining
  • * Quarterly revenue trends and pipeline advancement
  • * Debt refinancing ability and covenant compliance status

INO Financial Metrics

Revenue
$65.3K
Net Income
$-84.9M
EPS (Diluted)
$-1.81
Free Cash Flow
$-88.9M
Total Assets
$74.3M
Cash Position
$44.3M

💡 AI Analyst Insight

INOVIO PHARMACEUTICALS, INC. presents a mixed fundamental picture. Review the detailed metrics above to form your own investment thesis.

INO Profitability Ratios

Gross Margin N/A
Operating Margin -132,871.3%
Net Margin -130,000.0%
ROE -352.5%
ROA -114.3%
FCF Margin -136,074.5%

INO vs Healthcare Sector

How INOVIO PHARMACEUTICALS, INC. compares to Healthcare sector averages

Net Margin
INO -130,000.0%
vs
Sector Avg 12.0%
INO Sector
ROE
INO -352.5%
vs
Sector Avg 15.0%
INO Sector
Current Ratio
INO 1.4x
vs
Sector Avg 2.0x
INO Sector
Debt/Equity
INO 2.6x
vs
Sector Avg 0.6x
INO Sector

Sector benchmarks are approximate industry averages. Actual sector performance may vary.

Is INO Overvalued or Undervalued?

Based on fundamental analysis, INOVIO PHARMACEUTICALS, INC. shows some fundamental concerns relative to the Healthcare sector in 2026.

Return on Equity
-352.5%
Sector avg: 15%
Net Profit Margin
-130,000.0%
Sector avg: 12%
Revenue Growth
N/A
Year-over-year
Debt/Equity
2.60x
Sector avg: 0.6x

Note: This is a fundamental analysis based on SEC filings. For P/E ratio, price targets, and market-based valuation, consult financial data providers. This is not investment advice.

INO Balance Sheet & Liquidity

Current Ratio
1.40x
Quick Ratio
1.40x
Debt/Equity
2.60x
Debt/Assets
67.6%
Interest Coverage
-488.22x
Long-term Debt
$62.8M

INO 5-Year Financial Trend & Growth Analysis

INO 5-year financial data: Year 2021: Revenue $7.4M, Net Income -$119.4M, EPS $-1.21. Year 2022: Revenue $10.3M, Net Income -$166.4M, EPS $-1.07. Year 2023: Revenue $10.3M, Net Income -$303.7M, EPS $-17.45. Year 2024: Revenue $832.0K, Net Income -$135.1M, EPS $-6.09. Year 2025: Revenue $217.8K, Net Income -$107.3M, EPS $-3.95.
Revenue
Net Income
EPS (right axis)

5-Year Trend Summary: INOVIO PHARMACEUTICALS, INC.'s revenue has declined by 97% over the 5-year period, indicating business contraction. The most recent EPS of $-3.95 indicates the company is currently unprofitable.

INO Growth Metrics (YoY)

Revenue Growth
N/A
Year-over-year
Net Income Growth
N/A
Year-over-year
EPS Growth
N/A
Earnings per share
FCF Margin
-136,074.5%
Free cash flow / Revenue

INO Quarterly Performance

Quarterly financial performance data for INOVIO PHARMACEUTICALS, INC. including revenue, net income, and earnings per share.
Quarter Revenue Net Income EPS
Q3 2025 N/A -$19.7M $-0.87
Q2 2025 N/A -$19.7M $-0.61
Q1 2025 N/A -$19.7M $-0.51
Q3 2024 N/A -$25.2M $-0.89
Q2 2024 $100.8K -$30.5M $-1.19
Q1 2024 N/A -$30.5M $-1.31
Q3 2023 $388.4K -$33.9M $-0.13
Q2 2023 $226.0K -$35.5M $-0.13

Data sourced from SEC EDGAR 10-Q quarterly filings. Figures may represent quarterly or cumulative values.

INO Capital Allocation

Operating Cash Flow
-$88.6M
Cash generated from operations
Capital Expenditures
$285.7K
Investment in assets
Dividends
None
No dividend program

INO SEC 10-K & 10-Q Filing Analysis

Access official SEC EDGAR filings for INOVIO PHARMACEUTICALS, INC. (CIK: 0001055726)

📋 Recent SEC Filings

Date Form Document Action
Mar 12, 2026 8-K ino-20260312.htm View →
Mar 12, 2026 10-K ino-20251231.htm View →
Mar 5, 2026 4 xslF345X05/wk-form4_1772747737.xml View →
Mar 5, 2026 4 xslF345X05/wk-form4_1772747707.xml View →
Mar 5, 2026 4 xslF345X05/wk-form4_1772747679.xml View →

Frequently Asked Questions about INO

What is the AI rating for INO?

INOVIO PHARMACEUTICALS, INC. (INO) has an AI rating of STRONG SELL with 92% confidence, based on fundamental analysis of SEC EDGAR filings.

What are INO's key strengths?

Claude: Net loss improved 20.8% YoY suggesting margin stabilization from peak losses. Current ratio of 1.40x provides adequate short-term liquidity cushion.

What are the risks of investing in INO?

Claude: Revenue collapsed 70% YoY indicating loss of commercial traction or pipeline setback. Negative free cash flow of -$88.9M with only $44.3M cash on hand indicates runway of ~6 months at current burn rate.

What is INO's revenue and growth?

INOVIO PHARMACEUTICALS, INC. reported revenue of $65.3K.

Does INO pay dividends?

INOVIO PHARMACEUTICALS, INC. does not currently pay dividends.

Where can I find INO SEC filings?

Official SEC filings for INOVIO PHARMACEUTICALS, INC. (CIK: 0001055726) including 10-K, 10-Q, and 8-K reports are available on SEC EDGAR.

What is INO's EPS?

INOVIO PHARMACEUTICALS, INC. has a diluted EPS of $-1.81.

How is the AI analysis conducted?

Two independent AI systems — Claude (Anthropic) and ChatGPT (OpenAI) — analyze SEC EDGAR filings including 10-K annual reports and 10-Q quarterly reports. Each AI evaluates financial health, profitability ratios, balance sheet strength, and growth metrics. The combined rating reflects both perspectives for balanced insights.

Is INO a good stock to buy right now?

Based on our AI fundamental analysis in March 2026, INOVIO PHARMACEUTICALS, INC. has a STRONG SELL rating with 92% confidence. Review the strengths and risks sections above before making a decision. This is not investment advice.

Is INO stock overvalued or undervalued?

Valuation metrics for INO: ROE of -352.5% (sector avg: 15%), net margin of -130,000.0% (sector avg: 12%). Compare these metrics with sector averages to assess valuation.

Should I buy INO stock in 2026?

Our dual AI analysis gives INOVIO PHARMACEUTICALS, INC. a combined STRONG SELL rating for 2026. Revenue is data pending, with profitability at or below sector average. Always conduct your own research.

What is INO's free cash flow?

INOVIO PHARMACEUTICALS, INC.'s operating cash flow is $-88.6M, with capital expenditures of $285.7K. FCF margin is -136,074.5%.

How does INO compare to other Healthcare stocks?

Vs Healthcare sector averages: Net margin -130,000.0% (avg: 12%), ROE -352.5% (avg: 15%), current ratio 1.40 (avg: 2).

Disclaimer: This analysis is generated by Claude AI (Anthropic) and ChatGPT (OpenAI) based on publicly available SEC EDGAR filings. It does not include stock price data and should not be considered financial advice. All fundamental data is sourced from SEC public domain filings. Always conduct your own research and consult with a qualified financial advisor before making investment decisions.
Data Source: SEC EDGAR | Analysis Date: Mar 29, 2026 | Data as of: 2025-12-31 | Powered by Claude AI