IOVA vs IONS: Which is Better to Buy in 2026?

Side-by-side fundamental comparison based on AI analysis of SEC filings

AI Verdict

IONS has stronger fundamentals based on our AI analysis.

IOVA
IOVANCE BIOTHERAPEUTICS, INC.
STRONG SELL
92%
Confidence
VS
IONS
IONIS PHARMACEUTICALS INC
SELL
85%
Confidence

IOVA vs IONS Fundamental Comparison

Metric IOVA IONS
Revenue $263.5M $203.3M
Net Income $-391.0M $-381.4M
Net Margin -148.4% -187.6%
ROE -56.0% -78.0%
ROA -42.8% -10.8%
Current Ratio 3.20x 3.83x
Debt/Equity 0.00x 3.71x
EPS $-1.09 $-2.38

Green = Better metric | Red = Weaker metric

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IOVA vs IONS: Frequently Asked Questions

Is IOVA or IONS a better buy in 2026?

Based on dual AI fundamental analysis (Claude and ChatGPT), IONS has stronger fundamentals. IOVA is rated STRONG SELL (92% confidence) while IONS is rated SELL (85% confidence). This is not investment advice.

How does IOVA compare to IONS fundamentally?

IOVANCE BIOTHERAPEUTICS, INC. has ROE of -56.0% vs IONIS PHARMACEUTICALS INC's -78.0%. Net margins are -148.4% vs -187.6% respectively.

Which stock pays higher dividends, IOVA or IONS?

IOVA has a dividend yield of N/A or no dividend while IONS has N/A or no dividend. Check individual stock pages for detailed dividend history and payout ratios.

Should I invest in IOVA or IONS for long term?

For long-term investing, consider that IOVA has STRONG SELL rating with 92% confidence, while IONS has SELL rating with 85% confidence. Higher confidence indicates more consistent fundamentals from SEC filings. This is not investment advice - always do your own research.

What do the AI models say about IOVA vs IONS?

Our dual AI system (Claude by Anthropic and ChatGPT by OpenAI) analyzes SEC 10-K and 10-Q filings independently. For IOVA vs IONS, the AI consensus favors IONS based on fundamental metrics including revenue growth, profitability, ROE, and balance sheet strength.